The NF (Nuclear factor)-κB inhibitor parthenolide interacts with histone deacetylase inhibitors to induce MKK7/JNK1-dependent apoptosis in human acute myeloid leukaemia cells.
about
Natural Compound Histone Deacetylase Inhibitors (HDACi): Synergy with Inflammatory Signaling Pathway Modulators and Clinical Applications in CancerParthenolide promotes apoptotic cell death and inhibits the migration and invasion of SW620 cells.Histone deacetylase inhibitor (HDACI) mechanisms of action: emerging insights.Parthenolide Sensitizes Human Colorectal Cancer Cells to Tumor Necrosis Factor-related Apoptosis-inducing Ligand through Mitochondrial and Caspase Dependent Pathway.Anti-cancer activity of carbamate derivatives of melampomagnolide B.Rational Combinations of Targeted Agents in AMLEndogenous modulators and pharmacological inhibitors of histone deacetylases in cancer therapy.Bortezomib interacts synergistically with belinostat in human acute myeloid leukaemia and acute lymphoblastic leukaemia cells in association with perturbations in NF-κB and BimResveratrol sensitizes acute myelogenous leukemia cells to histone deacetylase inhibitors through reactive oxygen species-mediated activation of the extrinsic apoptotic pathwayParthenolide reduces the frequency of ABCB5-positive cells and clonogenic capacity of melanoma cells from anchorage independent melanospheres.Alpinetin suppresses proliferation of human hepatoma cells by the activation of MKK7 and elevates sensitization to cis-diammined dichloridoplatium.The NAE inhibitor pevonedistat interacts with the HDAC inhibitor belinostat to target AML cells by disrupting the DDR.JNK1/2 expression and modulation of STAT3 signaling in oral cancer.Dimers of Melampomagnolide B Exhibit Potent Anticancer Activity against Hematological and Solid Tumor CellsParthenolide, a sesquiterpene lactone, expresses multiple anti-cancer and anti-inflammatory activities.Sesquiterpene lactones: adverse health effects and toxicity mechanisms.Romidepsin for the treatment of non-Hodgkin's lymphoma.Biology and Clinical Relevance of Acute Myeloid Leukemia Stem Cells.Parthenolide induces apoptosis and lytic cytotoxicity in Epstein-Barr virus-positive Burkitt lymphoma.Combined effect of Hsp90 inhibitor geldanamycin and parthenolide via reactive oxygen species-mediated apoptotic process on epithelial ovarian cancer cells.Cyclic AMP efflux inhibitors as potential therapeutic agents for leukemia.Fanconi Anemia Mesenchymal Stromal Cells-Derived Glycerophospholipids Skew Hematopoietic Stem Cell Differentiation Through Toll-Like Receptor Signaling.Inflammatory Signaling Pathways in Preleukemic and Leukemic Stem Cells.Indole carboxylic acid esters of melampomagnolide B are potent anticancer agents against both hematological and solid tumor cells.Combination Therapies Targeting HDAC and IKK in Solid Tumors.Parthenolide facilitates apoptosis and reverses drug-resistance of human gastric carcinoma cells by inhibiting the STAT3 signaling pathway.Hsp72 Is an Intracellular Target of the α,β-Unsaturated Sesquiterpene Lactone, Parthenolide.
P2860
Q28073020-7285FB24-DB1E-44DF-AF23-659CBA6ACBE6Q33679117-6C3B0CD0-9607-4084-8F0A-818620EE6141Q33983255-29DC6CFC-819D-48D5-AD99-CA39154A6BB2Q34378553-22DC61FD-12D3-4F47-B4B8-1F371D5F4DB0Q35239721-3394374A-D5B8-4AC3-89D4-438BB58A54E6Q35750491-8B1F1367-7F78-41C2-8F5B-E9AD375DBF7FQ35975127-7D1CF81F-57D1-4472-AC45-B73934BBC727Q35982670-9A04591D-6806-4A3F-852C-66F9FC49B1F1Q36412841-E8142F6A-EF3C-44BA-9C35-11706688FE32Q36608707-51107337-75FE-43EA-A432-CF4011127ADCQ36642740-A555BF51-0E33-4906-AEC2-AEAC76C41AB0Q36876973-18039E27-6642-45F6-9C3C-6D46971F1FE7Q37002662-ECD1A3B6-87F1-433A-813F-DEFF9FCE008BQ37122892-01C00C9F-09A7-4D8C-8EEF-AE5DF3DB0CBBQ37878390-E49F3188-FB0D-43D6-821D-5B1B36904463Q38123215-592EFDB0-203D-4162-BCE3-396A991ECA53Q38455740-B673BA15-761A-44B4-A3D6-AA234D9032D5Q38537879-AC05F19D-B810-4328-89A7-D15A6879B9BBQ39324686-24F4BC4A-1342-4921-930F-5EDE6CA9AC1BQ39376431-5A23E4F8-4240-4757-97F8-E06B187927AFQ39809596-4928EBC3-FCAA-4C6A-87F0-B5B67DE231AAQ43203905-18495B23-ABB7-4299-AC21-E128A2C000ADQ47116205-13B5F06A-C858-4E30-ACA4-AED42D31BBB3Q48034568-A74CE929-5483-4E53-A552-BA948896F5CAQ49887757-117E4FCA-46D5-44B4-9EAF-FEFB41AEE838Q50191951-9E47E036-E2C9-440E-AA6E-7AD2696455F5Q55717236-06ACB932-CCFC-47D5-BBD4-19E6DEF1C773
P2860
The NF (Nuclear factor)-κB inhibitor parthenolide interacts with histone deacetylase inhibitors to induce MKK7/JNK1-dependent apoptosis in human acute myeloid leukaemia cells.
description
2010 nî lūn-bûn
@nan
2010 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
The NF (Nuclear factor)-κB inh ...... acute myeloid leukaemia cells.
@ast
The NF (Nuclear factor)-κB inh ...... acute myeloid leukaemia cells.
@en
The NF
@nl
type
label
The NF (Nuclear factor)-κB inh ...... acute myeloid leukaemia cells.
@ast
The NF (Nuclear factor)-κB inh ...... acute myeloid leukaemia cells.
@en
The NF
@nl
prefLabel
The NF (Nuclear factor)-κB inh ...... acute myeloid leukaemia cells.
@ast
The NF (Nuclear factor)-κB inh ...... acute myeloid leukaemia cells.
@en
The NF
@nl
P2093
P2860
P1476
The NF (Nuclear factor)-κB inh ...... acute myeloid leukaemia cells.
@en
P2093
Craig T Jordan
Monica L Guzman
Shuang Chen
Sin-Kei Yeung
Steven Grant
Xin-Yan Pei
P2860
P356
10.1111/J.1365-2141.2010.08319.X
P407
P50
P577
2010-08-02T00:00:00Z