Identification of a low-molecular weight TrkB antagonist with anxiolytic and antidepressant activity in mice
about
Virogenetic and optogenetic mechanisms to define potential therapeutic targets in psychiatric disordersBDNF rescues BAF53b-dependent synaptic plasticity and cocaine-associated memory in the nucleus accumbensThe neurotrophic receptor Ntrk2 directs lymphoid tissue neovascularization during Leishmania donovani infectionAnodal transcranial direct current stimulation boosts synaptic plasticity and memory in mice via epigenetic regulation of Bdnf expression.R-ketamine: a rapid-onset and sustained antidepressant without psychotomimetic side effectsRole of Keap1-Nrf2 signaling in depression and dietary intake of glucoraphanin confers stress resilience in mice7, 8-Dihydroxyflavone Protects an Endothelial Cell Line from H2O2 DamageEnriched Environment Attenuates Surgery-Induced Impairment of Learning, Memory, and Neurogenesis Possibly by Preserving BDNF Expression.Sex differences in stress-induced social withdrawal: role of brain derived neurotrophic factor in the bed nucleus of the stria terminalis.Genome-wide association for fear conditioning in an advanced intercross mouse lineThe Concise Guide to PHARMACOLOGY 2013/14: catalytic receptors.Epigenetic inheritance of a cocaine-resistance phenotype.Acute TrkB inhibition rescues phenobarbital-resistant seizures in a mouse model of neonatal ischemiaBrain plasticity and cognitive functions after ethanol consumption in C57BL/6J miceFlux of signalling endosomes undergoing axonal retrograde transport is encoded by presynaptic activity and TrkBDopamine D3 receptor is necessary for ethanol consumption: an approach with buspironeNeurotrophin receptor TrkB promotes lung adenocarcinoma metastasis.BDNF released during neuropathic pain potentiates NMDA receptors in primary afferent terminalsEpigenetic regulation of spinal cord gene expression controls opioid-induced hyperalgesia.Small-molecule modulation of neurotrophin receptors: a strategy for the treatment of neurological disease.Antidepressant effects of TrkB ligands on depression-like behavior and dendritic changes in mice after inflammation.Comparison of ketamine, 7,8-dihydroxyflavone, and ANA-12 antidepressant effects in the social defeat stress model of depression.BDNF-TrkB signaling in the nucleus accumbens shell of mice has key role in methamphetamine withdrawal symptoms.HBZ stimulates brain-derived neurotrophic factor/TrkB autocrine/paracrine signaling to promote survival of human T-cell leukemia virus type 1-Infected T cellsNeurotrophins are expressed in giant cell arteritis lesions and may contribute to vascular remodeling.An HDAC-dependent epigenetic mechanism that enhances the efficacy of the antidepressant drug fluoxetine.Neurotrophin signaling via TrkB and TrkC receptors promotes the growth of brain tumor-initiating cells.TrkB receptor signaling in the nucleus tractus solitarius mediates the food intake-suppressive effects of hindbrain BDNF and leptin.A novel form of synaptic plasticity in field CA3 of hippocampus requires GPER1 activation and BDNF releaseProtease-activated receptor 2 activation is sufficient to induce the transition to a chronic pain stateVariant brain-derived neurotrophic factor (Valine66Methionine) polymorphism contributes to developmental and estrous stage-specific expression of anxiety-like behavior in female mice.Neuroprotective Effects of Voluntary Exercise in an Inherited Retinal Degeneration Mouse Model.Role of TrkB during the postnatal development of the rat carotid body.The pharmacology of nociceptor primingRole of brain-derived neurotrophic factor in the excitatory-inhibitory imbalance during the critical period of postnatal respiratory development in the ratNeuropeptide Trefoil Factor 3 Reverses Depressive-Like Behaviors by Activation of BDNF-ERK-CREB Signaling in Olfactory Bulbectomized Rats.BDNF Induces Striatal-Enriched Protein Tyrosine Phosphatase 61 Degradation Through the Proteasome.Tau-Driven Neuronal and Neurotrophic Dysfunction in a Mouse Model of Early Tauopathy.Role of hippocampal p11 in the sustained antidepressant effect of ketamine in the chronic unpredictable mild stress modelSystemic Delivery of a Brain-Penetrant TrkB Antagonist Reduces Cocaine Self-Administration and Normalizes TrkB Signaling in the Nucleus Accumbens and Prefrontal Cortex.
P2860
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P2860
Identification of a low-molecular weight TrkB antagonist with anxiolytic and antidepressant activity in mice
description
2011 nî lūn-bûn
@nan
2011 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Identification of a low-molecu ...... ntidepressant activity in mice
@ast
Identification of a low-molecu ...... ntidepressant activity in mice
@en
Identification of a low-molecu ...... ntidepressant activity in mice
@nl
type
label
Identification of a low-molecu ...... ntidepressant activity in mice
@ast
Identification of a low-molecu ...... ntidepressant activity in mice
@en
Identification of a low-molecu ...... ntidepressant activity in mice
@nl
prefLabel
Identification of a low-molecu ...... ntidepressant activity in mice
@ast
Identification of a low-molecu ...... ntidepressant activity in mice
@en
Identification of a low-molecu ...... ntidepressant activity in mice
@nl
P2093
P2860
P356
P1476
Identification of a low-molecu ...... ntidepressant activity in mice
@en
P2093
Andre Mann
Christoph Kellendonk
Didier Rognan
Joël Prémont
P2860
P304
P356
10.1172/JCI43992
P407
P577
2011-04-18T00:00:00Z