Illustration of SSMD, z score, SSMD*, z* score, and t statistic for hit selection in RNAi high-throughput screens.

Illustration of SSMD, z score, SSMD, z score, and t statistic for hit selection in RNAi high-throughput screens.

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High-throughput identification of genotype-specific cancer vulnerabilities in mixtures of barcoded tumor cell lines Regulators of autophagosome formation in Drosophila muscles A Genome-Wide RNA Interference Screen Identifies a Role for Wnt/β-Catenin Signaling during Rift Valley Fever Virus Infection High content analysis of primary macrophages hosting proliferating Leishmania amastigotes: application to anti-leishmanial drug discovery A Novel High Content Imaging-Based Screen Identifies the Anti-Helminthic Niclosamide as an Inhibitor of Lysosome Anterograde Trafficking and Prostate Cancer Cell Invasion A High-Content Larval Zebrafish Brain Imaging Method for Small Molecule Drug Discovery A negative feedback loop mediated by the Bcl6-cullin 3 complex limits Tfh cell differentiation A genome-wide RNAi screen identifies factors required for distinct stages of C. elegans piRNA biogenesis Comprehensive analysis of high-throughput screens with HiTSeekR Automated selection of regions of interest for intensity-based FRET analysis of transferrin endocytic trafficking in normal vs. cancer cells High-Throughput RT-PCR for small-molecule screening assays GUItars: a GUI tool for analysis of high-throughput RNA interference screening data.Rapid Assessment and Visualization of Normality in High-Content and Other Cell-Level Data and Its Impact on the Interpretation of Experimental Results.Impact of normalization methods on high-throughput screening data with high hit rates and drug testing with dose-response data.Data Analysis for High-Throughput RNAi Screening.A high throughput mechanical screening device for cartilage tissue engineering.Targeted genetic dependency screen facilitates identification of actionable mutations in FGFR4, MAP3K9, and PAK5 in lung cancer Large-scale screening identifies a novel microRNA, miR-15a-3p, which induces apoptosis in human cancer cell lines.A male and female gametocyte functional viability assay to identify biologically relevant malaria transmission-blocking drugs Comparison of activity indexes for recognizing enzyme mutants of higher activity with uricase as model Large-scale screens of miRNA-mRNA interactions unveiled that the 3'UTR of a gene is targeted by multiple miRNAs A high-throughput assay to identify modifiers of premature chromosome condensation.Acetyl-CoA synthetase 2 promotes acetate utilization and maintains cancer cell growth under metabolic stress An open source based high content screening method for cell biology laboratories investigating cell spreading and adhesion Viability of developmental stages of Schistosoma mansoni quantified with xCELLigence worm real-time motility assay (xWORM).TRIM25 Enhances the Antiviral Action of Zinc-Finger Antiviral Protein (ZAP).Improved fluorescence assays to measure the defects associated with F508del-CFTR allow identification of new active compounds.A genome-wide RNAi screening method to discover novel genes involved in virus infection A Dual Microscopy-Based Assay To Assess Listeria monocytogenes Cellular Entry and Vacuolar Escape.Staged anticonvulsant screening for chronic epilepsy.Discovery and functional prioritization of Parkinson's disease candidate genes from large-scale whole exome sequencing.Pharmacological assessment defines Leishmania donovani casein kinase 1 as a drug target and reveals important functions in parasite viability and intracellular infection.Stability of the human pregnane X receptor is regulated by E3 ligase UBR5 and serine/threonine kinase DYRK2.Advances in zebrafish chemical screening technologies.Dereplication: racing to speed up the natural products discovery process.High-content drug screening for rare diseases.ARQiv-HTS, a versatile whole-organism screening platform enabling in vivo drug discovery at high-throughput rates.ZNStress: a high-throughput drug screening protocol for identification of compounds modulating neuronal stress in the transgenic mutant sod1G93R zebrafish model of amyotrophic lateral sclerosis Kinome-wide screening of HER2+ breast cancer cells for molecules that mediate cell proliferation or sensitize cells to trastuzumab therapy.A microscopic phenotypic assay for the quantification of intracellular mycobacteria adapted for high-throughput/high-content screening.

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P2860

Illustration of SSMD, z score, SSMD, z score, and t statistic for hit selection in RNAi high-throughput screens.

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http://www.wikidata.org/entity/Q34180188

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2011 nî lūn-bûn

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2011 թուականի Ապրիլին հրատարակուած գիտական յօդուած

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2011 թվականի ապրիլին հրատարակված գիտական հոդված

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2011年の論文

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