Identification of mutations in a new gene encoding a FERM family protein with a pleckstrin homology domain in Kindler syndrome.
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Kindlin-1 is a phosphoprotein involved in regulation of polarity, proliferation, and motility of epidermal keratinocytesLeukocyte adhesion deficiency-III is caused by mutations in KINDLIN3 affecting integrin activation.The integrin co-activator Kindlin-3 is expressed and functional in a non-hematopoietic cell, the endothelial cell.Increased cytoplasmic level of migfilin is associated with higher grades of human leiomyosarcomaKindlin-1 regulates integrin dynamics and adhesion turnoverKindlin-2 controls bidirectional signaling of integrinsNew perspectives on amelotin and amelogenesisDiverse functions of kindlin/fermitin proteins during embryonic development in Xenopus laevis.Loss of Kindlin-1 causes skin atrophy and lethal neonatal intestinal epithelial dysfunction.Talins and kindlins: partners in integrin-mediated adhesion.The Kindler syndrome protein is regulated by transforming growth factor-beta and involved in integrin-mediated adhesion.Opposite role of Kindlin-1 and Kindlin-2 in lung cancers.Oxidative stress and mitochondrial dysfunction in Kindler syndrome.Site-specific phosphorylation of kindlin-3 protein regulates its capacity to control cellular responses mediated by integrin αIIbβ3.Translational benefits from research on rare genodermatoses.Kindlin-2 controls TGF-β signalling and Sox9 expression to regulate chondrogenesisNMR Characterization and Membrane Interactions of the Loop Region of Kindlin-3 F1 Subdomain.A novel large deletion mutation of FERMT1 gene in a Chinese patient with Kindler syndrome.Kindlin-3 interacts with the ribosome and regulates c-Myc expression required for proliferation of chronic myeloid leukemia cellsKindlin-2 directly binds actin and regulates integrin outside-in signalingMendelian forms of periodontitis.Kindlins: essential regulators of integrin signalling and cell-matrix adhesion.Kindlin ignites a new flameLoss-of-function FERMT1 mutations in kindler syndrome implicate a role for fermitin family homolog-1 in integrin activation.Focal adhesion: a focal point in current cell biology and molecular medicineLocalization and potential function of kindlin-1 in periodontal tissues.Merlin and the ERM proteins--regulators of receptor distribution and signaling at the cell cortex.Oral manifestations in the epidermolysis bullosa spectrum.Adhesion and migration, the diverse functions of the laminin alpha3 subunit.Kindlins in FERM adhesion.Kindler syndrome: extension of FERMT1 mutational spectrum and natural history.Unusual and recently described cutaneous atrophic disorders.Cell-matrix adhesion of podocytes in physiology and disease.Inherited blistering skin diseases: underlying molecular mechanisms and emerging therapies.Costamere proteins and their involvement in myopathic processes.RhoA activation by CNFy restores cell-cell adhesion in kindlin-2-deficient keratinocytes.Novel focal adhesion protein kindlin-2 promotes the invasion of gastric cancer cells through phosphorylation of integrin β1 and β3.Kindlin-1 and -2 have overlapping functions in epithelial cells implications for phenotype modification.Kindlin-1 Regulates Keratinocyte Electrotaxis.Colocalization of kindlin-1, kindlin-2, and migfilin at keratinocyte focal adhesion and relevance to the pathophysiology of Kindler syndrome.
P2860
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P2860
Identification of mutations in a new gene encoding a FERM family protein with a pleckstrin homology domain in Kindler syndrome.
description
2003 nî lūn-bûn
@nan
2003 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
Identification of mutations in ...... gy domain in Kindler syndrome.
@ast
Identification of mutations in ...... gy domain in Kindler syndrome.
@en
Identification of mutations in ...... gy domain in Kindler syndrome.
@nl
type
label
Identification of mutations in ...... gy domain in Kindler syndrome.
@ast
Identification of mutations in ...... gy domain in Kindler syndrome.
@en
Identification of mutations in ...... gy domain in Kindler syndrome.
@nl
prefLabel
Identification of mutations in ...... gy domain in Kindler syndrome.
@ast
Identification of mutations in ...... gy domain in Kindler syndrome.
@en
Identification of mutations in ...... gy domain in Kindler syndrome.
@nl
P2093
P50
P356
P1476
Identification of mutations in ...... gy domain in Kindler syndrome.
@en
P2093
Bakar Bouadjar
Christina Has
Florence Jobard
Frédéric Caux
Fumi Matsuda
Jean-François Prud'homme
Judith Fischer
P304
P356
10.1093/HMG/DDG097
P577
2003-04-01T00:00:00Z