Solution single-vesicle assay reveals PIP2-mediated sequential actions of synaptotagmin-1 on SNAREs. - Wikidata - wikimedia - TriplyDB

Solution single-vesicle assay reveals PIP2-mediated sequential actions of synaptotagmin-1 on SNAREs.

Solution single-vesicle assay reveals PIP2-mediated sequential actions of synaptotagmin-1 on SNAREs.

http://www.wikidata.org/entity/Q34190825

about

Dynamic binding mode of a Synaptotagmin-1-SNARE complex in solution Complexins: small but capable Phosphatidylinositol 4,5-bisphosphate clusters act as molecular beacons for vesicle recruitment Injured astrocytes are repaired by Synaptotagmin XI-regulated lysosome exocytosis.Cis- and trans-membrane interactions of synaptotagmin-1 An extended helical conformation in domain 3a of Munc18-1 provides a template for SNARE (soluble N-ethylmaleimide-sensitive factor attachment protein receptor) complex assembly.SNAREpin assembly by Munc18-1 requires previous vesicle docking by synaptotagmin 1.Rapid fusion of synaptic vesicles with reconstituted target SNARE membranes Synaptotagmin interaction with SNAP-25 governs vesicle docking, priming, and fusion triggering.Calcium sensitive ring-like oligomers formed by synaptotagmin Synaptotagmin-7 is an asynchronous calcium sensor for synaptic transmission in neurons expressing SNAP-23 Molecular origins of synaptotagmin 1 activities on vesicle docking and fusion pore opening.Munc18a does not alter fusion rates mediated by neuronal SNAREs, synaptotagmin, and complexin Synaptotagmin-1 is an antagonist for Munc18-1 in SNARE zippering.β-Amyloid and α-synuclein cooperate to block SNARE-dependent vesicle fusion The synaptotagmin 1 linker may function as an electrostatic zipper that opens for docking but closes for fusion pore opening.Real-time submillisecond single-molecule FRET dynamics of freely diffusing molecules with liposome tethering.The synaptotagmin juxtamembrane domain is involved in neuroexocytosis.Vacuolar SNARE protein transmembrane domains serve as nonspecific membrane anchors with unequal roles in lipid mixing.Studying protein-reconstituted proteoliposome fusion with content indicators in vitro.Calcium binding promotes conformational flexibility of the neuronal Ca(2+) sensor synaptotagmin.Complexin arrests a pool of docked vesicles for fast Ca2+-dependent release.Towards reconstitution of membrane fusion mediated by SNAREs and other synaptic proteins Fusion pore formation and expansion induced by Ca2+ and synaptotagmin 1.Large α-synuclein oligomers inhibit neuronal SNARE-mediated vesicle docking.The blockade of the neurotransmitter release apparatus by botulinum neurotoxins.Molecular mechanisms of atlastin-mediated ER membrane fusion revealed by a FRET-based single-vesicle fusion assay.The phospholipid code: a key component of dying cell recognition, tumor progression and host-microbe interactions SNARE and regulatory proteins induce local membrane protrusions to prime docked vesicles for fast calcium-triggered fusion.C2-domain containing calcium sensors in neuroendocrine secretion.The Multifaceted Role of SNARE Proteins in Membrane Fusion.Amyloid-β Oligomers May Impair SNARE-Mediated Exocytosis by Direct Binding to Syntaxin 1a.Emerging Functional Differences between the Synaptotagmin and Ferlin Calcium Sensor Families.Productive and Non-productive Pathways for Synaptotagmin 1 to Support Ca2+-Triggered Fast Exocytosis.Botulinum Toxins A and E Inflict Dynamic Destabilization on t-SNARE to Impair SNARE Assembly and Membrane Fusion.Low hippocampal PI(4,5)P₂ contributes to reduced cognition in old mice as a result of loss of MARCKS.Mechanism of neurotransmitter release coming into focus

P2860

Q26269828-97BE3985-BCC2-48E4-926F-BAA4705F6061 Q26798363-C1C91CCA-47FC-461E-ABB6-B32A644DC813 Q27678096-BE1B0698-0367-4809-8ABE-1F3CFBEF96DE Q28508854-A9494AE6-3E8D-4EDD-86DB-99362A74C165 Q28575486-C118CA05-605F-4CB0-99C9-AD40BCBF78AF Q30273576-50A76620-6040-4B3E-A678-7E36F8D5C223 Q30273692-C0F8FFDA-2824-4787-A8B7-ED55CA976D00 Q30413162-DF2CDC00-6748-4248-9C45-6EF22D16519A Q33923426-05D72CFC-5D92-4174-A417-5043FD1A6008 Q34281080-C7BEEECD-BC54-4766-86B5-601C498B9FCB Q34572301-8B4B712A-0DA4-40FE-9086-3CEDC5770FA0 Q35198186-ABDA0AFA-CD66-4771-BC8F-54DB4ACFD762 Q35451364-ED9C374D-353E-4DD3-8B71-441A7B841C08 Q35451381-FBD9353C-3D43-46C4-A904-2FF8B4186DF0 Q35551615-79BB5341-0248-441A-98D7-15DD12C5985E Q35564940-2F10F5A4-FF11-4776-B6D3-0F0D55AC1A00 Q35574911-83F720A5-B45D-450A-BA9A-A0C64AF2DA0A Q35594101-D5CFA415-297F-4E87-994D-87E823DBD6D5 Q35608147-3CDC5317-D84B-40F0-8283-CE281E8A8DD0 Q35676286-2672F441-C16A-487A-BCE5-F744D4465508 Q35687725-5FBB0320-6CFD-4B53-BA5A-7715ED04B911 Q36137565-ABE00CC8-DE53-48D2-8EED-703997FB89DB Q36357369-D4A7A1E5-E842-4878-BAC6-22E0FDFA6F51 Q36567991-C35525DA-1AFD-4819-8E62-29C724C19044 Q36673364-A29393B8-EF70-4A5B-8C2E-FB720F402360 Q38113138-5873AAA3-186F-4FBD-837B-E1E656C3F6BD Q38399694-CA87DF65-4F73-4DFC-A38B-B8FBD1E79297 Q38602808-1B4E7B65-C50F-4C41-8054-D614B0F680F6 Q38798689-4CF10EA8-31A8-4601-9C08-CC1067B21842 Q38978762-37739843-F765-42BB-8DFB-48919BCAA2E4 Q39121037-53D887C5-A1FD-456E-9FA9-47AB6B91351E Q42409562-17855F32-0D26-4363-BC60-F9814ED2A988 Q47096382-7DFD398B-A870-4F13-A53A-05DA9DE6CD9A Q47137529-01A51684-DC60-4227-A9AC-16EB11B33A3F Q47651010-502FD1FD-0D0E-4EDB-9090-116AB3F7728B Q48151677-4C411EC5-52DF-4B9D-B4D8-9DEBC680EABE Q57173506-49ED63BB-3865-4F77-9D20-900B208674D1

P2860

Solution single-vesicle assay reveals PIP2-mediated sequential actions of synaptotagmin-1 on SNAREs.

http://www.wikidata.org/entity/Q34190825

description

2012 nî lūn-bûn

@nan

2012 թուականի Մարտին հրատարակուած գիտական յօդուած

@hyw

2012 թվականի մարտին հրատարակված գիտական հոդված

@hy

2012年の論文

@ja

2012年学术文章

@wuu

2012年学术文章

@zh-cn

2012年学术文章

@zh-hans

2012年学术文章

@zh-my

2012年学术文章

@zh-sg

2012年學術文章

@yue

name

Solution single-vesicle assay ...... of synaptotagmin-1 on SNAREs.

@ast

Solution single-vesicle assay ...... of synaptotagmin-1 on SNAREs.

@en

Solution single-vesicle assay ...... of synaptotagmin-1 on SNAREs.

@nl

type

label

Solution single-vesicle assay ...... of synaptotagmin-1 on SNAREs.

@ast

Solution single-vesicle assay ...... of synaptotagmin-1 on SNAREs.

@en

Solution single-vesicle assay ...... of synaptotagmin-1 on SNAREs.

@nl

prefLabel

Solution single-vesicle assay ...... of synaptotagmin-1 on SNAREs.

@ast

Solution single-vesicle assay ...... of synaptotagmin-1 on SNAREs.

@en

Solution single-vesicle assay ...... of synaptotagmin-1 on SNAREs.

@nl

P1433

Q34190825-A1E604D8-E9FB-4E8B-B94D-CAE78259F915

P1476

Q34190825-AC87D529-B799-48F7-8270-27EE8D57142B

P2093

Q34190825-1A4D82AB-87A1-4B22-9259-547E91E28FFB

Q34190825-1D9D2700-9361-4CEB-B8DA-7DFD0A0E9F49

Q34190825-51C25D7E-A813-4B9A-AE7A-CC220FC56E7C

Q34190825-542F55A2-2A92-46F1-AA7A-D7FBA1A6E94F

Q34190825-87D95E1D-2286-408A-BD80-02D5C0C0381B

Q34190825-9E9CA64C-02BC-4747-B99E-C226456C2E55

Q34190825-EAE62819-E8BF-4CC0-8C1C-2535AFE9253C

P2860

Q34190825-0029701A-1C8E-4FC8-AC5A-9FE439FA2529

Q34190825-0661D268-03CD-42E1-A3D9-9043B4B6C0C1

Q34190825-0AB59393-6335-4D56-9017-355CCECDAA70

Q34190825-10C70AA6-CA79-4BD2-A10F-202ABF0E19E4

Q34190825-121A06C0-7B05-4D99-908F-BC94F6C3C64D

Q34190825-148CAB39-1941-4E7B-9350-70A4CC8F248F

Q34190825-1768F079-C752-4083-8621-9F9514871A14

Q34190825-19B35FBF-F573-4FE2-8877-E211591D6E93

Q34190825-1C1E0A3C-8362-433C-B2A1-DD97E7F2D9E5

Q34190825-1C32B897-BA10-4F40-B1DB-27040108FF75

P304

Q34190825-796C9D52-3766-4180-A0CE-9718E4D6994F

P31

Q34190825-AC9C6379-5591-4A03-A056-0424DB69C823

P356

Q34190825-3325734E-B2E7-4373-85E6-186BD34A782B

P407

Q34190825-5ECEF287-119F-42BE-A114-D2742C38F5B9

P433

Q34190825-864AB81F-CEEC-4A06-8E7E-3251EBE21C73

P478

Q34190825-AF6A7C8B-FBAE-4D36-A909-ECDA85B52257

P577

Q34190825-15DE06DF-0219-4365-A579-5587ADADA266

P5875

Q34190825-79404AD1-16C9-4367-8418-9DCE719599D1

P698

Q34190825-15EC8ECC-0101-49CC-99AC-31870C4C681E

P932

Q34190825-8BE1FA74-03FE-4D69-B6AB-4A7FEA6A6E76

P356

P1433

The EMBO Journal

P1476

Solution single-vesicle assay ...... of synaptotagmin-1 on SNAREs.

@en

P2093

Bong-Kyu Choi

http://www.w3.org/2001/XMLSchema#string

Jae-Yeol Kim

http://www.w3.org/2001/XMLSchema#string

Mal-Gi Choi

http://www.w3.org/2001/XMLSchema#string

Nam Ki Lee

http://www.w3.org/2001/XMLSchema#string

Sun-Ae Kim

http://www.w3.org/2001/XMLSchema#string

Yeon-Kyun Shin

http://www.w3.org/2001/XMLSchema#string

Ying Lai

http://www.w3.org/2001/XMLSchema#string

P2860

The synaptic vesicle cycle

Membrane fusion: grappling with SNARE and SM proteins

Dynamic Ca2+-dependent stimulation of vesicle fusion by membrane-anchored synaptotagmin 1

Initial transcription by RNA polymerase proceeds through a DNA-scrunching mechanism

Crystal structure of a SNARE complex involved in synaptic exocytosis at 2.4 A resolution

How synaptotagmin promotes membrane fusion.

Synaptotagmin activates membrane fusion through a Ca2+-dependent trans interaction with phospholipids.

SNAREpins: minimal machinery for membrane fusion

Synaptotagmin I functions as a calcium regulator of release probability

Ca2+-dependent synaptotagmin binding to SNAP-25 is essential for Ca2+-triggered exocytosis

P304

2144-2155

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1038/EMBOJ.2012.57

http://www.w3.org/2001/XMLSchema#string

P407

P433

9

http://www.w3.org/2001/XMLSchema#string

P478

31

http://www.w3.org/2001/XMLSchema#string

P577

2012-03-09T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

221693287

http://www.w3.org/2001/XMLSchema#string

P698

22407297

http://www.w3.org/2001/XMLSchema#string

P932

3343461

http://www.w3.org/2001/XMLSchema#string