The Wnt signaling pathway and its role in tumor development.
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Nuclear localization of beta-catenin involved in precancerous change in oral leukoplakiaType I collagen promotes epithelial-mesenchymal transition through ILK-dependent activation of NF-kappaB and LEF-1Amer1/WTX couples Wnt-induced formation of PtdIns(4,5)P2 to LRP6 phosphorylationStructural and functional characterization of the Wnt inhibitor APC membrane recruitment 1 (Amer1)Human BCAS3 expression in embryonic stem cells and vascular precursors suggests a role in human embryogenesis and tumor angiogenesisAn LRP5 receptor with internal deletion in hyperparathyroid tumors with implications for deregulated WNT/beta-catenin signalingAkt is negatively regulated by the MULAN E3 ligaseLEF1 in androgen-independent prostate cancer: regulation of androgen receptor expression, prostate cancer growth, and invasionOncogenic function of ATDC in pancreatic cancer through Wnt pathway activation and beta-catenin stabilizationMutations in AXIN2 cause familial tooth agenesis and predispose to colorectal cancerFunctional interaction between Wnt3 and Frizzled-7 leads to activation of the Wnt/beta-catenin signaling pathway in hepatocellular carcinoma cellsThe Wnt-dependent signaling pathways as target in oncology drug discoveryThe links between axin and carcinogenesisChibby promotes adipocyte differentiation through inhibition of beta-catenin signalingGlycogen synthase kinase-3 (GSK3): inflammation, diseases, and therapeuticsEfficacy of Wnt-1 monoclonal antibody in sarcoma cellsNuclear-cytoplasmic shuttling of Chibby controls beta-catenin signaling.Chibby cooperates with 14-3-3 to regulate beta-catenin subcellular distribution and signaling activityReactive oxygen species mediate Cr(VI)-induced carcinogenesis through PI3K/AKT-dependent activation of GSK-3β/β-catenin signalingCadmium induces carcinogenesis in BEAS-2B cells through ROS-dependent activation of PI3K/AKT/GSK-3β/β-catenin signalingFZD1 regulates cumulus expansion genes and is required for normal female fertility in mice.Analysis of the expression profile of Dickkopf-1 gene in human glioma and the association with tumor malignancyVerification of predicted alternatively spliced Wnt genes reveals two new splice variants (CTNNB1 and LRP5) and altered Axin-1 expression during tumour progression.Common activation of canonical Wnt signaling in pancreatic adenocarcinoma.The internally truncated LRP5 receptor presents a therapeutic target in breast cancerGlycogen synthase kinase-3 inhibition disrupts nuclear factor-kappaB activity in pancreatic cancer, but fails to sensitize to gemcitabine chemotherapyChibby forms a homodimer through a heptad repeat of leucine residues in its C-terminal coiled-coil motif.Molecular analysis of the APC and MUTYH genes in Galician and Catalonian FAP families: a different spectrum of mutations?EpCAM nuclear localization identifies aggressive thyroid cancer and is a marker for poor prognosisAxin downregulates TCF-4 transcription via beta-catenin, but not p53, and inhibits the proliferation and invasion of lung cancer cells.Interplay between neural-cadherin and vascular endothelial-cadherin in breast cancer progression.LRP6 overexpression defines a class of breast cancer subtype and is a target for therapy.Molecular docking studies of flavonoids for their inhibition pattern against β-catenin and pharmacophore model generation from experimentally known flavonoids to fabricate more potent inhibitors for Wnt signaling pathwayKallistatin antagonizes Wnt/β-catenin signaling and cancer cell motility via binding to low-density lipoprotein receptor-related protein 6WNT4 is required for normal ovarian follicle development and female fertility.S100A6 protein negatively regulates CacyBP/SIP-mediated inhibition of gastric cancer cell proliferation and tumorigenesis.AXIS inhibition protein 2, orofacial clefts and a family history of cancerRedefining the subcellular location and transport of APC: new insights using a panel of antibodies.Recurrent somatic mutation of FAT1 in multiple human cancers leads to aberrant Wnt activation.β-Catenin loss in hepatocytes promotes hepatocellular cancer after diethylnitrosamine and phenobarbital administration to mice.
P2860
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P2860
The Wnt signaling pathway and its role in tumor development.
description
2003 nî lūn-bûn
@nan
2003 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年学术文章
@wuu
2003年学术文章
@zh-cn
2003年学术文章
@zh-hans
2003年学术文章
@zh-my
2003年学术文章
@zh-sg
2003年學術文章
@yue
name
The Wnt signaling pathway and its role in tumor development.
@ast
The Wnt signaling pathway and its role in tumor development.
@en
The Wnt signaling pathway and its role in tumor development.
@nl
type
label
The Wnt signaling pathway and its role in tumor development.
@ast
The Wnt signaling pathway and its role in tumor development.
@en
The Wnt signaling pathway and its role in tumor development.
@nl
prefLabel
The Wnt signaling pathway and its role in tumor development.
@ast
The Wnt signaling pathway and its role in tumor development.
@en
The Wnt signaling pathway and its role in tumor development.
@nl
P1476
The Wnt signaling pathway and its role in tumor development.
@en
P2093
P2888
P304
P356
10.1007/S00432-003-0431-0
P577
2003-04-18T00:00:00Z