Compartmentation of G protein-coupled signaling pathways in cardiac myocytes.
about
Integrin and GPCR Crosstalk in the Regulation of ASM Contraction Signaling in AsthmaIloprost- and isoproterenol-induced increases in cAMP are regulated by different phosphodiesterases in erythrocytes of both rabbits and humansCardiac-specific overexpression of caveolin-3 induces endogenous cardiac protection by mimicking ischemic preconditioningPhosphodiesterases maintain signaling fidelity via compartmentalization of cyclic nucleotidesSpatial control of cAMP signalling in health and diseaseAlterations of cAMP-dependent signaling in dystrophic skeletal muscleInvestigation of cAMP microdomains as a path to novel cancer diagnosticsNuclear GPCRs in cardiomyocytes: an insider's view of β-adrenergic receptor signalingThe role of type 4 phosphodiesterases in generating microdomains of cAMP: large scale stochastic simulationsDynamic visualization of calcium-dependent signaling in cellular microdomainsCardiac myofilament regulation by protein phosphatase type 1alpha and CapZRemoval of the N-terminal extension of cardiac troponin I as a functional compensation for impaired myocardial beta-adrenergic signalingPhosphodiesterase 4B in the cardiac L-type Ca²⁺ channel complex regulates Ca²⁺ current and protects against ventricular arrhythmias in miceLocalization of functional endothelin receptor signaling complexes in cardiac transverse tubulesNitric oxide inhibition of adenylyl cyclase type 6 activity is dependent upon lipid rafts and caveolin signaling complexesBeta-cell-targeted overexpression of phosphodiesterase 3B in mice causes impaired insulin secretion, glucose intolerance, and deranged islet morphologycGMP Signals Modulate cAMP Levels in a Compartment-Specific Manner to Regulate Catecholamine-Dependent Signaling in Cardiac MyocytesPKA catalytic subunit compartmentation regulates contractile and hypertrophic responses to β-adrenergic signalingMechanisms of cyclic AMP compartmentation revealed by computational models.Regulation of nuclear PKA revealed by spatiotemporal manipulation of cyclic AMP.Computational models reduce complexity and accelerate insight into cardiac signaling networksPhosphodiesterase 4D is required for beta2 adrenoceptor subtype-specific signaling in cardiac myocytesCardiac troponin T, a sarcomeric AKAP, tethers protein kinase A at the myofilaments.cAMP-stimulated protein phosphatase 2A activity associated with muscle A kinase-anchoring protein (mAKAP) signaling complexes inhibits the phosphorylation and activity of the cAMP-specific phosphodiesterase PDE4D3.Fibroblast-specific expression of AC6 enhances beta-adrenergic and prostacyclin signaling and blunts bleomycin-induced pulmonary fibrosis.A uniform extracellular stimulus triggers distinct cAMP signals in different compartments of a simple cellSignaling epicenters: the role of caveolae and caveolins in volatile anesthetic induced cardiac protection.G-protein-coupled enzyme cascades have intrinsic properties that improve signal localization and fidelityActive site coupling in PDE:PKA complexes promotes resetting of mammalian cAMP signaling.Mammalian oocytes are targets for prostaglandin E2 (PGE2) action.Cardioprotective trafficking of caveolin to mitochondria is Gi-protein dependent.PKA-dependent and PKA-independent pathways for cAMP-regulated exocytosis.Effects of cholesterol depletion on compartmentalized cAMP responses in adult cardiac myocytes.Role of caveolae in cardiac protection.Human bronchial smooth muscle cells express adenylyl cyclase isoforms 2, 4, and 6 in distinct membrane microdomains.Local control of β-adrenergic stimulation: Effects on ventricular myocyte electrophysiology and Ca(2+)-transient.A low-dose β1-blocker in combination with milrinone improves intracellular Ca2+ handling in failing cardiomyocytes by inhibition of milrinone-induced diastolic Ca2+ leakage from the sarcoplasmic reticulumSystems analysis of PKA-mediated phosphorylation gradients in live cardiac myocytesThe evolving role of lipid rafts and caveolae in G protein-coupled receptor signaling: implications for molecular pharmacology.Multiple signalling pathways involved in beta2-adrenoceptor-mediated glucose uptake in rat skeletal muscle cells.
P2860
Q21296663-9C078B2D-F0C8-4B74-A418-B39744F188D4Q24316393-9054C695-DCF7-432E-9CD8-D529A88E2771Q24336120-D80AF884-EE2D-400A-9CEC-5850ACF62A8EQ26860508-B614B1C0-6592-4FEB-8F25-8ECD12D73D84Q26866056-5C67AD38-4429-4E8D-A629-57D922DC1833Q27003221-9239176F-173C-4498-9D47-8796FA908C9CQ27023080-411031DF-A1F6-4A66-B553-ABBACD7AE4E8Q27026973-68D1D884-50CF-4F13-BDA5-4A27F4F0A1A5Q27323091-FF354F18-CBC8-4061-B582-59F196D9D167Q28083397-C9DA3817-499D-42D1-97E0-0C708FE6E561Q28273888-23043934-AC1C-401E-8B7F-E72047750014Q28295123-C6302B94-1718-4AA1-ACBB-36CC6C002DAEQ28507989-7A2BCEB7-CB42-49B7-85E0-DD3A70F9C2EBQ28564626-40C73E96-1CF7-4873-8159-982E4A675B5EQ28573679-9E0E0722-45B4-4F95-B428-FCABBF8299E4Q28594896-8E9026DA-B63F-4B41-BDCE-169FEDC782A3Q29306674-9ED0F186-241E-4E2F-8102-BD39916AEFB2Q30408840-B086AEED-DA4B-48E6-A9D2-6EF01A601EABQ30412189-80FB56BE-0D91-4E50-8223-5E636E4AE536Q30424795-8FC5A3E5-9568-473A-9268-5A7DFB0A1FB1Q30428985-2E5F338E-5CF3-4F5D-AC4A-D3AB8B9CE60DQ33719524-EBC62578-B86F-48F0-AD86-DA3C796E4C5DQ33740489-FF5CC16A-2654-42EA-9FFA-B4476560CF57Q33799568-B918A3EF-E46B-4A3A-81A8-A3B91D761852Q33916995-7C244B5D-D0E7-49B1-9EDD-2E1FDBCAEA81Q33949069-D2C7C16A-FFE8-43CD-B89D-9AD195210018Q33993790-AEDE30F7-5A5A-4428-940A-27893A13BC6EQ34190090-9E08F3E2-9D4E-46DC-A6B0-F1B472750B5DQ34205089-48D25E54-F272-4629-B575-668BF1F183E7Q34335800-28B679B3-82AC-42A1-8D95-9EFB6D51BE08Q34449891-44B1E4DE-CC76-45FF-ADC2-473C5EA76F39Q34453808-6459E739-12AB-46AE-9B28-381DF7944532Q34629314-63A69638-CFB6-4187-B061-054613A407D3Q34634634-D81AAEDF-6CB0-4A68-BD68-D90B2E6DBD37Q34715744-BC585BD8-A56D-4D19-897F-F5488EC90B95Q34785976-21E7BBBF-E985-4E15-98A6-189969BD6AFCQ35007243-1E727FF0-500C-4371-B3EB-46BEDDF540DCQ35036534-8F22B25D-2B3A-4D9C-8C84-D21B8F264857Q35047674-3776267D-2E7F-4E54-B22F-66D1101E6DD5Q35100664-019D788E-3FBD-4571-B7B6-1C96629DB1C0
P2860
Compartmentation of G protein-coupled signaling pathways in cardiac myocytes.
description
2001 nî lūn-bûn
@nan
2001 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年学术文章
@wuu
2001年学术文章
@zh-cn
2001年学术文章
@zh-hans
2001年学术文章
@zh-my
2001年学术文章
@zh-sg
2001年學術文章
@yue
name
Compartmentation of G protein-coupled signaling pathways in cardiac myocytes.
@ast
Compartmentation of G protein-coupled signaling pathways in cardiac myocytes.
@en
Compartmentation of G protein-coupled signaling pathways in cardiac myocytes.
@nl
type
label
Compartmentation of G protein-coupled signaling pathways in cardiac myocytes.
@ast
Compartmentation of G protein-coupled signaling pathways in cardiac myocytes.
@en
Compartmentation of G protein-coupled signaling pathways in cardiac myocytes.
@nl
prefLabel
Compartmentation of G protein-coupled signaling pathways in cardiac myocytes.
@ast
Compartmentation of G protein-coupled signaling pathways in cardiac myocytes.
@en
Compartmentation of G protein-coupled signaling pathways in cardiac myocytes.
@nl
P1476
Compartmentation of G protein-coupled signaling pathways in cardiac myocytes.
@en
P2093
Brunton LL
Steinberg SF
P304
P356
10.1146/ANNUREV.PHARMTOX.41.1.751
P577
2001-01-01T00:00:00Z