Mindbomb 1, an E3 ubiquitin ligase, forms a complex with RYK to activate Wnt/β-catenin signaling - Wikidata - wikimedia - TriplyDB

Mindbomb 1, an E3 ubiquitin ligase, forms a complex with RYK to activate Wnt/β-catenin signaling

Mindbomb 1, an E3 ubiquitin ligase, forms a complex with RYK to activate Wnt/β-catenin signaling

http://www.wikidata.org/entity/Q34211643

about

Tumour suppressor RNF43 is a stem-cell E3 ligase that induces endocytosis of Wnt receptors The role of Ryk and Ror receptor tyrosine kinases in Wnt signal transduction Frizzled homolog proteins, microRNAs and Wnt signaling in cancer The Wnt receptor Ryk reduces neuronal and cell survival capacity by repressing FOXO activity during the early phases of mutant huntingtin pathogenicity miR-1/133a clusters cooperatively specify the cardiomyogenic lineage by adjustment of myocardin levels during embryonic heart development Activation of Wnt3a signaling stimulates intestinal epithelial repair by promoting c-Myc-regulated gene expression Mind bomb 1 is required for pancreatic β-cell formation WNT5A enhances resistance of melanoma cells to targeted BRAF inhibitors.The Wnt receptor Ryk is a negative regulator of mammalian dendrite morphogenesis Identification of potential synthetic lethal genes to p53 using a computational biology approach A fully human inhibitory monoclonal antibody to the Wnt receptor RYK New classes of mind bomb-interacting proteins identified from yeast two-hybrid screens.A tail of two sites: a bipartite mechanism for recognition of notch ligands by mind bomb E3 ligases.Nuclear signaling from cadherin adhesion complexes A new mib allele with a chromosomal deletion covering foxc1a exhibits anterior somite specification defect.Sequential Elution Interactome Analysis of the Mind Bomb 1 Ubiquitin Ligase Reveals a Novel Role in Dendritic Spine Outgrowth.The Wnt receptor Ryk plays a role in mammalian planar cell polarity signaling.The E3 ligase Mind bomb-1 (Mib1) modulates Delta-Notch signaling to control neurogenesis and gliogenesis in the developing spinal cord.Tethering of an E3 ligase by PCM1 regulates the abundance of centrosomal KIAA0586/Talpid3 and promotes ciliogenesis The E3 ubiquitin ligase mind bomb 1 ubiquitinates and promotes the degradation of survival of motor neuron protein.Structural determinants of adhesion by Protocadherin-19 and implications for its role in epilepsy.Genomic analyses reveal broad impact of miR-137 on genes associated with malignant transformation and neuronal differentiation in glioblastoma cells.A new genome scan for primary nonsyndromic vesicoureteric reflux emphasizes high genetic heterogeneity and shows linkage and association with various genes already implicated in urinary tract development.RNAi targeting GPR4 influences HMEC-1 gene expression by microarray analysis.Balanced ubiquitination determines cellular responsiveness to extracellular stimuli.Alternative Wnt pathways and receptors.Wnt signaling during cochlear development.The Yin and Yang of Wnt/Ryk axon guidance in development and regeneration.Protocadherins branch out: Multiple roles in dendrite development.Regulation of Wnt signaling by protocadherins.Centriolar Satellites Control GABARAP Ubiquitination and GABARAP-Mediated Autophagy.RYK promotes the stemness of glioblastoma cells via the WNT/ β-catenin pathway Receptor tyrosine kinase expression of circulating tumor cells in small cell lung cancer.Structure and function of the Mind bomb E3 ligase in the context of Notch signal transduction.Adhesion GPCR-Related Protein Networks.Ryk is essential for Wnt-5a-dependent invasiveness in human glioma.The γ-Protocadherin-C3 isoform inhibits canonical Wnt signalling by binding to and stabilizing Axin1 at the membrane.Related-to-receptor tyrosine kinase receptor regulates hematopoietic stem and progenitor sensitivity to myelosuppressive injury in mice.Extracellular LDLR repeats modulate Wnt signaling activity by promoting LRP6 receptor endocytosis mediated by the Itch E3 ubiquitin ligase.Endoderm Jagged induces liver and pancreas duct lineage in zebrafish

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Mindbomb 1, an E3 ubiquitin ligase, forms a complex with RYK to activate Wnt/β-catenin signaling

http://www.wikidata.org/entity/Q34211643

description

2011 nî lūn-bûn

@nan

2011 թուականի Օգոստոսին հրատարակուած գիտական յօդուած

@hyw

2011 թվականի օգոստոսին հրատարակված գիտական հոդված

@hy

2011年の論文

@ja

2011年論文

@yue

2011年論文

@zh-hant

2011年論文

@zh-hk

2011年論文

@zh-mo

2011年論文

@zh-tw

2011年论文

@wuu

name

Mindbomb 1, an E3 ubiquitin li ...... tivate Wnt/β-catenin signaling

@ast

Mindbomb 1, an E3 ubiquitin li ...... tivate Wnt/β-catenin signaling

@en

Mindbomb 1, an E3 ubiquitin li ...... tivate Wnt/β-catenin signaling

@nl

type

label

Mindbomb 1, an E3 ubiquitin li ...... tivate Wnt/β-catenin signaling

@ast

Mindbomb 1, an E3 ubiquitin li ...... tivate Wnt/β-catenin signaling

@en

Mindbomb 1, an E3 ubiquitin li ...... tivate Wnt/β-catenin signaling

@nl

prefLabel

Mindbomb 1, an E3 ubiquitin li ...... tivate Wnt/β-catenin signaling

@ast

Mindbomb 1, an E3 ubiquitin li ...... tivate Wnt/β-catenin signaling

@en

Mindbomb 1, an E3 ubiquitin li ...... tivate Wnt/β-catenin signaling

@nl

P1433

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P1476

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P2860

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P356

P1433

Journal of Cell Biology

P1476

Mindbomb 1, an E3 ubiquitin li ...... tivate Wnt/β-catenin signaling

@en

P2093

Atsushi Aoyagi

http://www.w3.org/2001/XMLSchema#string

Jamie N Anastas

http://www.w3.org/2001/XMLSchema#string

Jason D Berndt

http://www.w3.org/2001/XMLSchema#string

Lan Tang

http://www.w3.org/2001/XMLSchema#string

Peitzu Yang

http://www.w3.org/2001/XMLSchema#string

P2860

Caveolin is necessary for Wnt-3a-dependent internalization of LRP6 and accumulation of beta-catenin

Mammalian Ryk is a Wnt coreceptor required for stimulation of neurite outgrowth

Cytoscape: a software environment for integrated models of biomolecular interaction networks

A death-associated protein kinase (DAPK)-interacting protein, DIP-1, is an E3 ubiquitin ligase that promotes tumor necrosis factor-induced apoptosis and regulates the cellular levels of DAPK

STRING: a database of predicted functional associations between proteins

DAVID: Database for Annotation, Visualization, and Integrated Discovery

The Wnt signaling pathway in development and disease

Wilms tumor suppressor WTX negatively regulates WNT/beta-catenin signaling

Revelations of the RYK receptor

PAR-1 is a Dishevelled-associated kinase and a positive regulator of Wnt signalling

P304

737-750

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P31

scholarly article

P356

10.1083/JCB.201107021

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P407

P433

5

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P478

194

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P50

Randall T. Moon

P577

2011-08-29T00:00:00Z

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P5875

51603882

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P698

21875946

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P932

3171123

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