Tumour suppressor RNF43 is a stem-cell E3 ligase that induces endocytosis of Wnt receptors
about
Interaction with both ZNRF3 and LGR4 is required for the signalling activity of R-spondinMammary Development and Breast Cancer: A Wnt PerspectiveControl of Wnt Receptor Turnover by R-spondin-ZNRF3/RNF43 Signaling Module and Its Dysregulation in CancerFrizzled7: A Promising Achilles' Heel for Targeting the Wnt Receptor Complex to Treat CancerWnt signaling in cancer stem cells and colon cancer metastasisBridging academic science and clinical research in the search for novel targeted anti-cancer agentsChemical Disruption of Wnt-dependent Cell Fate Decision-making Mechanisms in Cancer and Regenerative MedicineKeeping Wnt signalosome in check by vesicular trafficThe gastrointestinal tumor microenvironmentG Protein-Coupled Receptor Signaling in Stem Cells and CancerMicroenvironmental control of stem cell fate in intestinal homeostasis and diseaseThe structural basis of R-spondin recognition by LGR5 and RNF43Structural basis for R-spondin recognition by LGR4/5/6 receptorsStructural and molecular basis of ZNRF3/RNF43 transmembrane ubiquitin ligase inhibition by the Wnt agonist R-spondinStructures of Wnt-Antagonist ZNRF3 and Its Complex with R-Spondin 1 and Implications for SignalingCurrent understanding concerning intestinal stem cellsFrizzled Receptors in Development and DiseaseDifferentiated Troy+ chief cells act as reserve stem cells to generate all lineages of the stomach epitheliumInteraction between DMRT1 function and genetic background modulates signaling and pluripotency to control tumor susceptibility in the fetal germ lineN-Glycosylation of Human R-Spondin 1 Is Required for Efficient Secretion and Stability but Not for Its Heparin Binding AbilityGenomic profiling reveals mutational landscape in parathyroid carcinomasCrystal structure of LGR4-Rspo1 complex: insights into the divergent mechanisms of ligand recognition by leucine-rich repeat G-protein-coupled receptors (LGRs).Intrinsic disorder in spondins and some of their interacting partners.Identifying cancer type specific oncogenes and tumor suppressors using limited size data.Whole-exome sequencing characterizes the landscape of somatic mutations and copy number alterations in adrenocortical carcinoma.Ring finger protein 43 associates with gastric cancer progression and attenuates the stemness of gastric cancer stem-like cells via the Wnt-β/catenin signaling pathway.Diversity of Precursor Lesions For Pancreatic Cancer: The Genetics and Biology of Intraductal Papillary Mucinous NeoplasmControl of signaling molecule range during developmental patterningThe Research Progress on Intestinal Stem Cells and Its Relationship with Intestinal Microbiota.Concise Review: The Potential Use of Intestinal Stem Cells to Treat Patients with Intestinal Failure.Norrin-induced Frizzled4 endocytosis and endo-lysosomal trafficking control retinal angiogenesis and barrier function.Salinomycin suppresses LRP6 expression and inhibits both Wnt/β-catenin and mTORC1 signaling in breast and prostate cancer cellsUpdating the Wnt pathways.RNF43 is frequently mutated in colorectal and endometrial cancersRecurrent chromosome 22 deletions in osteoblastoma affect inhibitors of the Wnt/beta-catenin signaling pathway.CD151-α3β1 integrin complexes suppress ovarian tumor growth by repressing slug-mediated EMT and canonical Wnt signaling.Integrative ChIP-seq/microarray analysis identifies a CTNNB1 target signature enriched in intestinal stem cells and colon cancerMicrosatellite stable colorectal cancers stratified by the BRAF V600E mutation show distinct patterns of chromosomal instability.Engineering high-potency R-spondin adult stem cell growth factors.Moving upstream in the war on WNTs.
P2860
18ec2b54b02755c488cf188cda8705ffad694f092a0996bf70af74b28bf55e79f592d869d2cb5d46442331215245e2354a97ca5383121bdad20908a170c922b456625bdbb736862654320aab012279f2ae49fba60b72e6fa6efc142dc4f9c4dcccba5852b0c7a5ee0ca50bfb5874a728f5d6b84b41c4b19fb268b72591b83caa00519ae341498a6807c3907ab874ebe1a3f205774d1717adc180fa47a069e681c9e6565518589042671e3f00f45f8b5518794481ccf247101841ed589798a97e739ba93643827d9f
P248
Q24338954-1AC1C5C7-83A4-47B6-BCC1-A850BF97473FQ26740086-3123B72A-375D-4349-8B81-3BAF771EFFF0Q26747432-CD3922AB-1F24-4E5D-851F-2380EEDA0EC1Q26747651-367879CD-D57E-4A20-8C12-42ECD230725EQ26748552-CA140B8A-6337-4B7C-BF29-08880159C629Q26771396-54568A53-8319-406F-8025-C393C16A36C5Q26796673-E62C504C-5697-4EF7-AD6E-9289EA48AD62Q26822956-04FC8B4F-DF0B-4327-A8C6-A12362B82EE4Q26827391-7FECAF4B-3428-4A12-9A7E-BBE7763CCC94Q26853233-0CA83D2E-E9BE-4D9A-B0C6-A4A615487405Q26999226-6A02F74D-2C76-4838-A9A3-2C3FDA741A91Q27678577-248F2CF1-625B-4759-B2EB-DDD45D6F4855Q27678579-7A859892-B93E-4357-8654-6FA1CEB8C8A1Q27680600-E37DA0C8-AC9E-4D3A-B654-7063833A153CQ27680931-931A2078-DDDD-4229-91F0-D79DD2B16B22Q27694486-0FD6F331-D2AC-4739-B2B6-1AE462A42B73Q28071320-082936E1-C551-45DF-B805-34B68EBBC339Q28300176-86027692-8DFE-4C06-AE94-76D3B6215467Q28508532-23BA359F-5883-4FE3-B13C-9C204DBCFEEDQ28828423-CC1FA047-BF45-4922-8497-3FBC92171E70Q30360213-21CE45A0-00D0-4230-8825-E1C0E1141949Q30369442-4A2CF5C3-B803-46D7-9A84-0FF4EB683467Q30399043-3D6D02F0-47AC-4FF1-94AE-C7EB390798C8Q31135256-DE7955EB-324A-4A04-97D0-2476DCF102D9Q33570215-5417DD58-478F-4B1A-91C9-B746059EB71AQ33608561-1E862D9B-8205-49F7-A0AE-5E3132CA6031Q33635144-F5325A35-67B4-4FA9-A5ED-EA960A28F869Q33639419-DBB48C99-D99D-4C2B-97F2-D4ED4E2EE01BQ33715483-92843A8C-5AAF-4CCB-93B8-314110A5D7FBQ33722414-E9F331FF-CB82-4E12-8B4E-B494BD297D08Q33882256-510A5576-E9C3-489F-8545-550D73263918Q34052780-C585CE22-C69D-40C2-91E3-71116C82656CQ34360489-5E1EB965-3757-497D-A979-92179B29F02EQ34817306-8B68BDE2-255A-4C12-890E-5ED3D5DF238BQ35044006-612A55F7-3DE7-49A4-AD42-C5FBC36AD1ADQ35067887-BCF732CB-D023-4A57-940D-C5D2667F76DFQ35126460-485EB557-57B6-49AA-9622-28BA8ADADA2CQ35126713-2011E044-9A47-4CDE-BEA6-ADD02153D1B0Q35156403-B0C2AC4A-F96E-452B-8344-AA8A8905558EQ35183964-17C0146A-B688-4BB4-B9EB-20B527EC09AB
P2860
Tumour suppressor RNF43 is a stem-cell E3 ligase that induces endocytosis of Wnt receptors
description
2012 nî lūn-bûn
@nan
2012 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2012 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
name
Tumour suppressor RNF43 is a s ...... s endocytosis of Wnt receptors
@ast
Tumour suppressor RNF43 is a s ...... s endocytosis of Wnt receptors
@en
Tumour suppressor RNF43 is a s ...... s endocytosis of Wnt receptors
@en-gb
Tumour suppressor RNF43 is a s ...... s endocytosis of Wnt receptors
@nl
type
label
Tumour suppressor RNF43 is a s ...... s endocytosis of Wnt receptors
@ast
Tumour suppressor RNF43 is a s ...... s endocytosis of Wnt receptors
@en
Tumour suppressor RNF43 is a s ...... s endocytosis of Wnt receptors
@en-gb
Tumour suppressor RNF43 is a s ...... s endocytosis of Wnt receptors
@nl
prefLabel
Tumour suppressor RNF43 is a s ...... s endocytosis of Wnt receptors
@ast
Tumour suppressor RNF43 is a s ...... s endocytosis of Wnt receptors
@en
Tumour suppressor RNF43 is a s ...... s endocytosis of Wnt receptors
@en-gb
Tumour suppressor RNF43 is a s ...... s endocytosis of Wnt receptors
@nl
P2093
P2860
P50
P921
P3181
P356
P1433
P1476
Tumour suppressor RNF43 is a s ...... s endocytosis of Wnt receptors
@en
P2093
Albert J R Heck
Johan H van Es
Marc van de Wetering
Maureen Spit
P2860
P2888
P3181
P356
10.1038/NATURE11308
P407
P50
P577
2012-08-30T00:00:00Z
P5875
P6179
1013338577