Life extension factor klotho prevents mortality and enhances cognition in hAPP transgenic mice. - Wikidata - wikimedia - TriplyDB

Life extension factor klotho prevents mortality and enhances cognition in hAPP transgenic mice.

Life extension factor klotho prevents mortality and enhances cognition in hAPP transgenic mice.

http://www.wikidata.org/entity/Q34462326

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Calorie Restriction Suppresses Age-Dependent Hippocampal Transcriptional Signatures.Longevity factor klotho and chronic psychological stress Secreted and Transmembrane αKlotho Isoforms Have Different Spatio-Temporal Profiles in the Brain during Aging and Alzheimer's Disease Progression Mini-review: Retarding aging in murine genetic models of neurodegeneration Increasing the Receptor Tyrosine Kinase EphB2 Prevents Amyloid-β-induced Depletion of Cell Surface Glutamate Receptors by a Mechanism That Requires the PDZ-binding Motif of EphB2 and Neuronal Activity.G-395A polymorphism in the promoter region of the KLOTHO gene associates with reduced cognitive impairment among the oldest old.Systemic klotho is associated with KLOTHO variation and predicts intrinsic cortical connectivity in healthy human aging.Klotho regulates postnatal neurogenesis and protects against age-related spatial memory loss.Molecular and cellular aspects of age-related cognitive decline and Alzheimer's disease.Klotho regulates CA1 hippocampal synaptic plasticity.Stemming the Alzheimer tsunami: introduction to the special issue on reserve and resilience in Alzheimer's disease.Peripheral Elevation of a Klotho Fragment Enhances Brain Function and Resilience in Young, Aging, and α-Synuclein Transgenic Mice.Secreted αKlotho isoform protects against age-dependent memory deficits.Correlation between KLOTHO gene and mild cognitive impairment in the Uygur and Han populations of Xinjiang.DPP-4 inhibition with linagliptin ameliorates the progression of premature aging in klotho-/- mice.Association between α-Klotho and Deep White Matter Lesions in the Brain: A Pilot Case Control Study Using Brain MRI.Behavioral Changes in Mice Lacking Interleukin-33.Human alternative Klotho mRNA is a nonsense-mediated mRNA decay target inefficiently spliced in renal disease.The Anti-Aging Protein Klotho Enhances Remyelination Following Cuprizone-Induced Demyelination.Serum Klotho, vitamin D, and homocysteine in combination predict the outcomes of Chinese patients with multiple system atrophy.The cannabis paradox: when age matters.Fluoxetine Treatment Induces Seizure Behavior and Premature Death in APPswe/PS1dE9 Mice.Modeled structural basis for the recognition of α2-3-sialyllactose by soluble Klotho.Aerobic exercise-stimulated Klotho upregulation extends life span by attenuating the excess production of reactive oxygen species in the brain and kidney Klotho, the Key to Healthy Brain Aging?

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Life extension factor klotho prevents mortality and enhances cognition in hAPP transgenic mice.

http://www.wikidata.org/entity/Q34462326

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2015 nî lūn-bûn

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2015 թուականի Փետրուարին հրատարակուած գիտական յօդուած

@hyw

2015 թվականի փետրվարին հրատարակված գիտական հոդված

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2015年の論文

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2015年学术文章

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2015年学术文章

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2015年学术文章

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2015年学术文章

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2015年学术文章

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2015年學術文章

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name

Life extension factor klotho p ...... ition in hAPP transgenic mice.

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Life extension factor klotho p ...... ition in hAPP transgenic mice.

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Life extension factor klotho p ...... ition in hAPP transgenic mice.

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Life extension factor klotho p ...... ition in hAPP transgenic mice.

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Life extension factor klotho p ...... ition in hAPP transgenic mice.

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Life extension factor klotho p ...... ition in hAPP transgenic mice.

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Life extension factor klotho p ...... ition in hAPP transgenic mice.

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Life extension factor klotho p ...... ition in hAPP transgenic mice.

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Life extension factor klotho p ...... ition in hAPP transgenic mice.

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JNEUROSCI.5791-12.2015

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Journal of Neuroscience

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Life extension factor klotho p ...... ition in hAPP transgenic mice.

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Alexander Betourne

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Carmela R Abraham

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Daniel Kim

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Dena B Dubal

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Eliezer Masliah

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Gui-Qiu Yu

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Kaitlyn Ho

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Lei Zhu

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Lennart Mucke

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Makoto Kuro-O

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P2860

Genetic enhancement of learning and memory in mice

Alzheimer mechanisms and therapeutic strategies

Association of human aging with a functional variant of klotho.

Mutation of the mouse klotho gene leads to a syndrome resembling ageing

Inhibitory interneuron deficit links altered network activity and cognitive dysfunction in Alzheimer model.

Amyloid-beta-induced neuronal dysfunction in Alzheimer's disease: from synapses toward neural networks

Levetiracetam suppresses neuronal network dysfunction and reverses synaptic and cognitive deficits in an Alzheimer's disease model.

Reversing EphB2 depletion rescues cognitive functions in Alzheimer model

Suppression of aging in mice by the hormone Klotho

Soluble oligomers of amyloid Beta protein facilitate hippocampal long-term depression by disrupting neuronal glutamate uptake

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10.1523/JNEUROSCI.5791-12.2015

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Kurtresha Worden

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273953612

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25673831

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