Caspase-8 regulates TNF-α-induced epithelial necroptosis and terminal ileitis. - Wikidata - wikimedia - TriplyDB

Caspase-8 regulates TNF-α-induced epithelial necroptosis and terminal ileitis.

Caspase-8 regulates TNF-α-induced epithelial necroptosis and terminal ileitis.

http://www.wikidata.org/entity/Q34216810

about

Many stimuli pull the necrotic trigger, an overview Necroptosis in tumorigenesis, activation of anti-tumor immunity, and cancer therapy Post-translational modifications as key regulators of TNF-induced necroptosis Inhibition of regulated cell death by cell-penetrating peptides Mechanisms of Microbe-Host Interaction in Crohn's Disease: Dysbiosis vs. Pathobiont Selection Converging roles of caspases in inflammasome activation, cell death and innate immunity Mitochondrial dysfunction in inflammatory bowel disease Apoptosis, Necrosis, and Necroptosis in the Gut and Intestinal Homeostasis Genetically engineered mouse models for studying inflammatory bowel disease The Intestinal Microbiota in Inflammatory Bowel Disease DED or alive: assembly and regulation of the death effector domain complexes Diet, microbiome, and the intestinal epithelium: an essential triumvirate?Fueling the flames: Mammalian programmed necrosis in inflammatory diseases Photoreceptor cell death and rescue in retinal detachment and degenerations Death receptor-ligand systems in cancer, cell death, and inflammation Viral infection and the evolution of caspase 8-regulated apoptotic and necrotic death pathways Role of necroptosis in the pathogenesis of solid organ injury Programmed necrosis in the cross talk of cell death and inflammation Rho-A prenylation and signaling link epithelial homeostasis to intestinal inflammation.Discovery of Small Molecule RIP1 Kinase Inhibitors for the Treatment of Pathologies Associated with Necroptosis NETosis in Cancer - Platelet-Neutrophil Crosstalk Promotes Tumor-Associated Pathology Facing Terminal Ileitis: Going Beyond Crohn's Disease Role of the protein tyrosine phosphatase Shp2 in homeostasis of the intestinal epithelium Lgr4 gene deficiency increases susceptibility and severity of dextran sodium sulfate-induced inflammatory bowel disease in mice Mlkl knockout mice demonstrate the indispensable role of Mlkl in necroptosis Survival function of the FADD-CASPASE-8-cFLIP(L) complex Protein tyrosine phosphatase SAP-1 protects against colitis through regulation of CEACAM20 in the intestinal epithelium Distinct roles of RIP1-RIP3 hetero- and RIP3-RIP3 homo-interaction in mediating necroptosis Diverse sequence determinants control human and mouse receptor interacting protein 3 (RIP3) and mixed lineage kinase domain-like (MLKL) interaction in necroptotic signaling Can probiotics modulate human disease by impacting intestinal barrier function?Key roles of necroptotic factors in promoting tumor growth Depletion of RIPK3 or MLKL blocks TNF-driven necroptosis and switches towards a delayed RIPK1 kinase-dependent apoptosis Boosting Apoptotic Cell Clearance by Colonic Epithelial Cells Attenuates Inflammation In Vivo Biomedical applications of ion mobility-enhanced data-independent acquisition-based label-free quantitative proteomics.Advanced endoscopic imaging for diagnosis of Crohn's disease Microbial products induce claudin-2 to compromise gut epithelial barrier function.Toll-like receptor-mediated down-regulation of the deubiquitinase cylindromatosis (CYLD) protects macrophages from necroptosis in wild-derived mice Advanced oxidation protein products induce intestine epithelial cell death through a redox-dependent, c-jun N-terminal kinase and poly (ADP-ribose) polymerase-1-mediated pathway.Co-inhibition of NF-κB and JNK is synergistic in TNF-expressing human AML.Uncovering Pathogenic Mechanisms of Inflammatory Bowel Disease Using Mouse Models of Crohn's Disease-Like Ileitis: What is the Right Model?

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Caspase-8 regulates TNF-α-induced epithelial necroptosis and terminal ileitis.

http://www.wikidata.org/entity/Q34216810

description

2011 nî lūn-bûn

@nan

2011 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած

@hyw

2011 թվականի սեպտեմբերին հրատարակված գիտական հոդված

@hy

2011年の論文

@ja

2011年論文

@yue

2011年論文

@zh-hant

2011年論文

@zh-hk

2011年論文

@zh-mo

2011年論文

@zh-tw

2011年论文

@wuu

name

Caspase-8 regulates TNF-α-induced epithelial necroptosis and terminal ileitis.

@ast

Caspase-8 regulates TNF-α-induced epithelial necroptosis and terminal ileitis.

@en

Caspase-8 regulates TNF-α-induced epithelial necroptosis and terminal ileitis.

@nl

type

label

Caspase-8 regulates TNF-α-induced epithelial necroptosis and terminal ileitis.

@ast

Caspase-8 regulates TNF-α-induced epithelial necroptosis and terminal ileitis.

@en

Caspase-8 regulates TNF-α-induced epithelial necroptosis and terminal ileitis.

@nl

prefLabel

Caspase-8 regulates TNF-α-induced epithelial necroptosis and terminal ileitis.

@ast

Caspase-8 regulates TNF-α-induced epithelial necroptosis and terminal ileitis.

@en

Caspase-8 regulates TNF-α-induced epithelial necroptosis and terminal ileitis.

@nl

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Caspase-8 regulates TNF-α-induced epithelial necroptosis and terminal ileitis

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Benno Weigmann

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Claudia Günther

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Eva Martini

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Helmut Neumann

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Kerstin Amann

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Markus F Neurath

http://www.w3.org/2001/XMLSchema#string

Nadine Wittkopf

http://www.w3.org/2001/XMLSchema#string

Stephen M Hedrick

http://www.w3.org/2001/XMLSchema#string

P2860

Fas triggers an alternative, caspase-8-independent cell death pathway using the kinase RIP as effector molecule

Receptor interacting protein kinase-3 determines cellular necrotic response to TNF-alpha

Phosphorylation-driven assembly of the RIP1-RIP3 complex regulates programmed necrosis and virus-induced inflammation

Single Lgr5 stem cells build crypt-villus structures in vitro without a mesenchymal niche

Death effector domain-containing proteins

Catalytic activity of the caspase-8-FLIP(L) complex inhibits RIPK3-dependent necrosis

RIP3, an energy metabolism regulator that switches TNF-induced cell death from apoptosis to necrosis

Inflammatory bowel disease

Molecular mechanisms of necroptosis: an ordered cellular explosion

Identification of RIP1 kinase as a specific cellular target of necrostatins

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10.1038/NATURE10400

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7364

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Christoph Becker

Maximilian Waldner

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2011-09-14T00:00:00Z

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253071795

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