Direct regulation of GAS6/AXL signaling by HIF promotes renal metastasis through SRC and MET. - Wikidata - wikimedia - TriplyDB

Direct regulation of GAS6/AXL signaling by HIF promotes renal metastasis through SRC and MET.

Direct regulation of GAS6/AXL signaling by HIF promotes renal metastasis through SRC and MET.

http://www.wikidata.org/entity/Q34217927

about

Cabozantinib in the treatment of advanced renal cell carcinoma: design, development, and potential place in the therapy Hypoxic control of metastasis Targeting hypoxic response for cancer therapy Progress toward overcoming hypoxia-induced resistance to solid tumor therapy The Receptor Tyrosine Kinase AXL in Cancer Progression Cabozantinib in the treatment of advanced renal cell carcinoma: clinical trial evidence and experience Ligand Activation of TAM Family Receptors-Implications for Tumor Biology and Therapeutic Response Implications of Hypoxia in Breast Cancer Metastasis to Bone For robust big data analyses: a collection of 150 important pro-metastatic genes KDM4B/JMJD2B is a p53 target gene that modulates the amplitude of p53 response after DNA damage.Cabozantinib versus Everolimus in Advanced Renal-Cell Carcinoma AXL is a potential therapeutic target in dedifferentiated and pleomorphic liposarcomas.Anti-Tumor Effects of Second Generation β-Hydroxylase Inhibitors on Cholangiocarcinoma Development and Progression.Cabozantinib Versus Sunitinib As Initial Targeted Therapy for Patients With Metastatic Renal Cell Carcinoma of Poor or Intermediate Risk: The Alliance A031203 CABOSUN Trial.Novel Axl-driven signaling pathway and molecular signature characterize high-grade ovarian cancer patients with poor clinical outcome.Repurposing the anti-malarial drug artesunate as a novel therapeutic agent for metastatic renal cell carcinoma due to its attenuation of tumor growth, metastasis, and angiogenesis.Global phosphotyrosine survey in triple-negative breast cancer reveals activation of multiple tyrosine kinase signaling pathways.Normalization of TAM post-receptor signaling reveals a cell invasive signature for Axl tyrosine kinase.Hypoxia, Hypoxia-inducible Transcription Factors, and Renal Cancer.Reprogramming the immunological microenvironment through radiation and targeting Axl.Inhibition of the GAS6/AXL pathway augments the efficacy of chemotherapies.New treatment options for metastatic renal cell carcinoma with prior anti-angiogenesis therapy Cabozantinib: an Active Novel Multikinase Inhibitor in Renal Cell Carcinoma.AXL modulates extracellular matrix protein expression and is essential for invasion and metastasis in endometrial cancer.Sunitinib activates Axl signaling in renal cell cancer.Gene of the month: Axl.Giving AXL the axe: targeting AXL in human malignancy.Targeting MET and AXL overcomes resistance to sunitinib therapy in renal cell carcinoma.Novel therapeutic options for second-line therapy in metastatic renal cell carcinoma.Axl and Mer Receptor Tyrosine Kinases: Distinct and Nonoverlapping Roles in Inflammation and Cancer?The Wide Experience of the Sequential Therapy for Patients with Metastatic Renal Cell Carcinoma.Cabozantinib for the treatment of renal cell carcinoma.AXL receptor tyrosine kinase as a therapeutic target in NSCLC.Key Roles of AXL and MER Receptor Tyrosine Kinases in Resistance to Multiple Anticancer Therapies.Renal cell carcinoma: molecular characterization and evolving treatment paradigms.LncRNA HOTAIR regulates HIF-1α/AXL signaling through inhibition of miR-217 in renal cell carcinoma Molecular analysis of alternative transcripts of equine AXL receptor tyrosine kinase gene A comprehensive analysis of cancer-driving mutations and genes in kidney cancer.Protein S drives oral squamous cell carcinoma tumorigenicity through regulation of AXL.Small molecule inhibitors block Gas6-inducible TAM activation and tumorigenicity

P2860

Q26741450-B1C30E89-001A-4A1D-9BE7-3CDD690DDAA7 Q26749159-F10D5728-6CF4-4D12-9FB4-5E7C74C235D3 Q26767351-1B0F64AD-6742-489B-9582-0F0B6E6C293E Q26796405-3598AAE8-9354-43EA-9214-29438D4D5215 Q28068756-BF758B9F-5512-4CC3-AF67-F225EC399983 Q28072166-8F11B756-EB0B-4C2F-89F6-FF69C8F8C391 Q28072503-84EC6EA3-B094-47F2-ADD8-ECEE8A4F4B15 Q28077444-F59840DB-73A2-4CA5-BD6F-C1F2A34C1A3C Q31155755-C187B925-A95D-4297-A2C9-CF9D4C8F7F39 Q33580494-7A13CAB6-B5D4-45A7-B4E6-6AFAD160DAB9 Q34495684-0B5B9035-80E5-468E-BCB1-A0387FF1B3A4 Q35843071-3B92117A-73AB-4662-B801-0A8441E1D885 Q35949450-075E5671-A8AF-48DB-B5AA-1209C5672E99 Q36281483-B57E1F4E-5C51-4ACB-8B78-0D4BE851B426 Q36544445-74A7C4FB-1A11-4738-811F-5880E01F5DDA Q36545062-F998A526-5E06-499A-A0DF-6436A58C474A Q36557240-53296486-6DB7-4D0B-B1B1-0D3C94E649DC Q37233198-2BD8A4C8-1849-4D21-8A32-48329EF9AE97 Q37234734-4D2FE9A1-702A-498B-A3A8-B074C8BD1963 Q37541688-D957870B-C197-4167-A4B6-4E9900BC7A7E Q37545045-3F62EE8D-4AA6-4483-9FF1-B0E436E67960 Q37620907-E11257E3-E9A4-48E0-A3E9-1CD9D500577B Q37672483-FADB0F9E-C992-48B1-9CB5-66375518B219 Q37684598-599909F2-CAC6-4449-889C-3D72AD5B37E5 Q38451761-544BA8F2-EFD6-45A6-9AD3-929878FD4EE7 Q38763966-DBB83E10-FCEE-4759-A8BF-76318AF595B7 Q38772267-4287F285-7406-445B-A1E9-F658196CA4E7 Q38835745-D0BC9418-E6B4-48E4-AEDD-40FBE38FE4D8 Q38868038-58533B7D-8982-4245-BA88-AB94D3C7D9E4 Q38936702-855258F0-7876-4EC2-8A68-AE56E8C8CB3E Q38950573-9E50F6AC-530A-49AE-82C3-EDCD79ECB4ED Q39005403-F9294A2B-CDF9-450C-9294-270F4BCE3E78 Q39139917-2620CEBA-343E-4BB7-B995-2135902E33E4 Q39157476-36D45E6B-5BEC-435D-A281-963B40378258 Q39157961-EBEEF9C6-A371-4CF4-A21C-17EB2B6A492B Q41082549-22DF729C-EA72-402D-A415-02ACAECF453C Q41600499-AB84BCCE-58C9-47C5-B05F-B922CD2C9C93 Q41839294-6FA70786-F256-4CE0-A66D-2E5EEED31E88 Q41847773-A8BC82A9-E1AB-44C1-9569-7A89775B6FD0 Q41940444-C9045886-F2AE-4227-B623-619F379BEB6C

P2860

Direct regulation of GAS6/AXL signaling by HIF promotes renal metastasis through SRC and MET.

http://www.wikidata.org/entity/Q34217927

description

2014 nî lūn-bûn

@nan

2014 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած

@hyw

2014 թվականի սեպտեմբերին հրատարակված գիտական հոդված

@hy

2014年の論文

@ja

2014年論文

@yue

2014年論文

@zh-hant

2014年論文

@zh-hk

2014年論文

@zh-mo

2014年論文

@zh-tw

2014年论文

@wuu

name

Direct regulation of GAS6/AXL ...... etastasis through SRC and MET.

@ast

Direct regulation of GAS6/AXL ...... etastasis through SRC and MET.

@en

Direct regulation of GAS6/AXL ...... etastasis through SRC and MET.

@nl

type

label

Direct regulation of GAS6/AXL ...... etastasis through SRC and MET.

@ast

Direct regulation of GAS6/AXL ...... etastasis through SRC and MET.

@en

Direct regulation of GAS6/AXL ...... etastasis through SRC and MET.

@nl

prefLabel

Direct regulation of GAS6/AXL ...... etastasis through SRC and MET.

@ast

Direct regulation of GAS6/AXL ...... etastasis through SRC and MET.

@en

Direct regulation of GAS6/AXL ...... etastasis through SRC and MET.

@nl

P1433

Q34217927-BA134423-B715-4D4E-9049-2C369B21095C

P1476

Q34217927-EC18244C-9461-4322-B871-C9491AFC463A

P2093

Q34217927-12A55CE3-421D-4F8A-9ED9-B54FC45276C3

Q34217927-1D8FA3B0-2E09-4DEE-AB03-67293AD99909

Q34217927-2B91DDB4-28CC-41C1-B870-B2A7F8062C5A

Q34217927-4D551152-A19C-4772-B160-F259FB03259B

Q34217927-5C0EB8D6-93BD-4919-BA59-8AF79E6B18D5

Q34217927-61919EF6-3FEF-437E-AEF4-81E3678390BA

Q34217927-969949C4-F096-4E25-B759-0654537E58B7

Q34217927-E72AC8BB-0B9F-4B4F-852A-78D6FE04EA0B

Q34217927-ECC1F898-0FC2-4223-9A04-2723541319FE

Q34217927-F7E2E7A0-A188-4BCC-97CA-4760D2FF4A87

P2860

Q34217927-04CCDA1C-222F-4924-87BC-C1D0A6AEA6FC

Q34217927-0C0ED68E-391C-454F-A94B-9ABB5F0219EF

Q34217927-0DED4DAA-5CF2-4A8E-863A-88CCBC5B8D6F

Q34217927-1065AEDB-7F9B-4E76-B833-71BA0765EE1F

Q34217927-14A6A89D-5DE2-493A-9C48-1938228A416B

Q34217927-1F705061-EA5E-4036-870C-E339591B8B82

Q34217927-1F9F0915-03CD-448D-85A1-251B6252B7A8

Q34217927-2041B389-C790-4D62-91B7-7115F0AFD73B

Q34217927-23560003-94A3-47E4-A6D4-5D305E93C73A

Q34217927-251E1EEC-091F-4961-824A-708A752A727C

P304

Q34217927-34F34115-8E89-48D7-982A-B252F767268A

P31

Q34217927-D17615DA-1770-4BE8-82AE-7C999CC76CC8

P356

Q34217927-DE7C1B69-DEB3-4C47-88A4-ED04630F0376

P407

Q34217927-68EB8CDC-8C8A-4126-9263-501B7BEACC6A

P433

Q34217927-DDA78DC4-B43D-427D-B947-CD5D7777B498

P478

Q34217927-3D06DFB3-8E5F-400F-9969-9F42910777E6

P50

Q34217927-4E08BB5A-A32F-4F03-9B64-D6FC6047C3BF

Q34217927-613401E5-FD68-4984-BB96-ED6DB72C6F44

Q34217927-B8BB238B-9642-49C1-B8B3-D05920EFF56E

P577

Q34217927-3FF072E2-DBEC-4C0A-9B55-C6D160C32BF5

P5875

Q34217927-78D5B087-A2FB-46EF-B936-A74D109DCB48

P698

Q34217927-4D7AB800-0CF5-4C7C-B898-EE55ADE8E940

P932

Q34217927-7BED31A9-B6F1-4E9F-93AC-93C0D2039E5B

P356

PNAS.1404848111

P1433

Proceedings of the National Academy of Sciences of the United States of America

P1476

Direct regulation of GAS6/AXL ...... metastasis through SRC and MET

@en

P2093

Amato J Giaccia

http://www.w3.org/2001/XMLSchema#string

Andy Chan

http://www.w3.org/2001/XMLSchema#string

Anh N Diep

http://www.w3.org/2001/XMLSchema#string

David Lindgren

http://www.w3.org/2001/XMLSchema#string

Edward L LaGory

http://www.w3.org/2001/XMLSchema#string

Elizabeth C Finger

http://www.w3.org/2001/XMLSchema#string

Håkan Axelson

http://www.w3.org/2001/XMLSchema#string

Kartik Viswanathan

http://www.w3.org/2001/XMLSchema#string

Laura Castellini

http://www.w3.org/2001/XMLSchema#string

Mihalis S Kariolis

http://www.w3.org/2001/XMLSchema#string

P2860

The tumour suppressor protein VHL targets hypoxia-inducible factors for oxygen-dependent proteolysis

HIFalpha targeted for VHL-mediated destruction by proline hydroxylation: implications for O2 sensing

Intracellular signaling of the Ufo/Axl receptor tyrosine kinase is mediated mainly by a multi-substrate docking-site

Inhibition of transcription elongation by the VHL tumor suppressor protein

Binding of the von Hippel-Lindau tumor suppressor protein to Elongin B and C

The von Hippel-Lindau tumor-suppressor gene product forms a stable complex with human CUL-2, a member of the Cdc53 family of proteins

Hypoxia-inducible factors in physiology and medicine

HIF1α and HIF2α: sibling rivalry in hypoxic tumour growth and progression

Targeting of HIF-alpha to the von Hippel-Lindau ubiquitylation complex by O2-regulated prolyl hydroxylation

Axl is essential for VEGF-A-dependent activation of PI3K/Akt

P304

13373-13378

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1073/PNAS.1404848111

http://www.w3.org/2001/XMLSchema#string

P407

P433

37

http://www.w3.org/2001/XMLSchema#string

P478

111

http://www.w3.org/2001/XMLSchema#string

P50

Erinn B. Rankin

Katherine C Fuh

P577

2014-09-03T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

265344346

http://www.w3.org/2001/XMLSchema#string

P698

25187556

http://www.w3.org/2001/XMLSchema#string

P932

4169907

http://www.w3.org/2001/XMLSchema#string