about
Hypoxic control of metastasisThe Receptor Tyrosine Kinase AXL in Cancer ProgressionInactivation of the arylhydrocarbon receptor nuclear translocator (Arnt) suppresses von Hippel-Lindau disease-associated vascular tumors in mice.Hypoxia-inducible factor-2 (HIF-2) regulates hepatic erythropoietin in vivoRegulation of the histone demethylase JMJD1A by hypoxia-inducible factor 1 alpha enhances hypoxic gene expression and tumor growth.A central role for hypoxic signaling in cartilage, bone, and hematopoiesis.PHD inhibition mitigates and protects against radiation-induced gastrointestinal toxicity via HIF2.DNA methylation down-regulates CDX1 gene expression in colorectal cancer cell lines.Direct regulation of GAS6/AXL signaling by HIF promotes renal metastasis through SRC and MET.Putative intestine-specific enhancers located in 5' sequence of the CDX1 gene regulate CDX1 expression in the intestine.Stable expression of HIF-1alpha in tubular epithelial cells promotes interstitial fibrosisHypoxic induction of AKAP12 variant 2 shifts PKA-mediated protein phosphorylation to enhance migration and metastasis of melanoma cells.Oxygen-sensing PHDs regulate bone homeostasis through the modulation of osteoprotegerin.Regulation of iron homeostasis by the hypoxia-inducible transcription factors (HIFs).AXL is an essential factor and therapeutic target for metastatic ovarian cancerThe HIF signaling pathway in osteoblasts directly modulates erythropoiesis through the production of EPO.Biology of the bone marrow microenvironment and myelodysplastic syndromes.Renal cyst development in mice with conditional inactivation of the von Hippel-Lindau tumor suppressorHypoxia-inducible factor-2 regulates vascular tumorigenesis in mice.Polycomb repressive complex 2 regulates skeletal growth by suppressing Wnt and TGF-β signallingThe role of hypoxia-inducible factors in tumorigenesis.Hypoxia-inducible factor 2 regulates hepatic lipid metabolism.Reprogramming the immunological microenvironment through radiation and targeting Axl.Inhibition of the GAS6/AXL pathway augments the efficacy of chemotherapies.CTGF is a therapeutic target for metastatic melanoma.AXL modulates extracellular matrix protein expression and is essential for invasion and metastasis in endometrial cancer.Osteoblasts: a novel source of erythropoietin.Hypoxia: Signaling the Metastatic Cascade.Loss of VHL in mesenchymal progenitors of the limb bud alters multiple steps of endochondral bone development.Bringing H2AX into the angiogenesis family.Regulation of Bone Marrow Angiogenesis by Osteoblasts during Bone Development and Homeostasis.Blood and bones: osteoblastic HIF signaling regulates erythropoiesis.
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description
hulumtuese
@sq
onderzoeker
@nl
researcher
@en
հետազոտող
@hy
name
Erinn B Rankin
@es
Erinn B. Rankin
@en
Erinn B. Rankin
@nl
Erinn B. Rankin
@sl
type
label
Erinn B Rankin
@es
Erinn B. Rankin
@en
Erinn B. Rankin
@nl
Erinn B. Rankin
@sl
prefLabel
Erinn B Rankin
@es
Erinn B. Rankin
@en
Erinn B. Rankin
@nl
Erinn B. Rankin
@sl
P106
P1153
7006034977
P21
P31
P496
0000-0002-2045-2296
P569
2000-01-01T00:00:00Z