Inhibition of the GAS6/AXL pathway augments the efficacy of chemotherapies.
about
Utilizing combinatorial engineering to develop Tie2 targeting antagonistic angiopoetin-2 ligands as candidates for anti-angiogenesis therapyPhospho-AXL is widely expressed in glioblastoma and associated with significant shorter overall survival.Small molecule inhibitors block Gas6-inducible TAM activation and tumorigenicityGAS6-expressing and self-sustaining cancer cells in 3D spheroids activate the PDK-RSK-mTOR pathway for survival and drug resistance.Anexelekto/MER tyrosine kinase inhibitor ONO-7475 arrests growth and kills FMS-like tyrosine kinase 3-internal tandem duplication mutant acute myeloid leukemia cells by diverse mechanisms.Small-Molecule Inhibition of Axl Targets Tumor Immune Suppression and Enhances Chemotherapy in Pancreatic Cancer.
P2860
Inhibition of the GAS6/AXL pathway augments the efficacy of chemotherapies.
description
2016 nî lūn-bûn
@nan
2016年の論文
@ja
2016年学术文章
@wuu
2016年学术文章
@zh-cn
2016年学术文章
@zh-hans
2016年学术文章
@zh-my
2016年学术文章
@zh-sg
2016年學術文章
@yue
2016年學術文章
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2016年學術文章
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name
Inhibition of the GAS6/AXL pathway augments the efficacy of chemotherapies.
@en
Inhibition of the GAS6/AXL pathway augments the efficacy of chemotherapies.
@nl
type
label
Inhibition of the GAS6/AXL pathway augments the efficacy of chemotherapies.
@en
Inhibition of the GAS6/AXL pathway augments the efficacy of chemotherapies.
@nl
prefLabel
Inhibition of the GAS6/AXL pathway augments the efficacy of chemotherapies.
@en
Inhibition of the GAS6/AXL pathway augments the efficacy of chemotherapies.
@nl
P2093
P2860
P356
P1476
Inhibition of the GAS6/AXL pathway augments the efficacy of chemotherapies.
@en
P2093
Amato J Giaccia
Dadi Jiang
Douglas S Jones
Irimpan I Mathews
Jennifer R Cochran
Mihalis S Kariolis
Monica M Olcina
Shannon E Nash
Shiven Kapur
P2860
P304
P356
10.1172/JCI85610
P407
P577
2016-11-28T00:00:00Z