Reduced axonal transport and increased excitotoxic retinal ganglion cell degeneration in mice transgenic for human mutant P301S tau. - Wikidata - wikimedia - TriplyDB

Reduced axonal transport and increased excitotoxic retinal ganglion cell degeneration in mice transgenic for human mutant P301S tau.

Reduced axonal transport and increased excitotoxic retinal ganglion cell degeneration in mice transgenic for human mutant P301S tau.

http://www.wikidata.org/entity/Q34230291

about

Oral Delivery of Protein Drugs Bioencapsulated in Plant Cells Generation of retinal ganglion cells with functional axons from human induced pluripotent stem cells.Stressor-dependent Alterations in Glycoprotein 130: Implications for Glial Cell Reactivity, Cytokine Signaling and Ganglion Cell Health in Glaucoma Long-term in vivo imaging of fibrillar tau in the retina of P301S transgenic mice.Increased CSF tau level is correlated with decreased lamina cribrosa thickness.PATHOLOGIES OF AXONAL TRANSPORT IN NEURODEGENERATIVE DISEASES The sphingolipid psychosine inhibits fast axonal transport in Krabbe disease by activation of GSK3β and deregulation of molecular motors.Distal retinal ganglion cell axon transport loss and activation of p38 MAPK stress pathway following VEGF-A antagonism.Tau pathology is present in vivo and develops in vitro in sensory neurons from human P301S tau transgenic mice: a system for screening drugs against tauopathies RNA silencing of genes involved in Alzheimer's disease enhances mitochondrial function and synaptic activity.Neuronal expression of pathological tau accelerates oligodendrocyte progenitor cell differentiation Synaptic Dysfunction in Alzheimer's Disease and Glaucoma: From Common Degenerative Mechanisms Toward Neuroprotection.Wallerian degeneration: an emerging axon death pathway linking injury and disease.Axonal transport defects in Alzheimer's disease.Retinal manifestations of Alzheimer's disease.Tau accumulation in the retina promotes early neuronal dysfunction and precedes brain pathology in a mouse model of Alzheimer's disease.Integrative properties of retinal ganglion cell electrical responsiveness depend on neurotrophic support and genotype in the mouse.Effects of neuroactive agents on axonal growth and pathfinding of retinal ganglion cells generated from human stem cells.Inflammatory changes in optic nerve after closed-head repeated traumatic brain injury: Preliminary study.Potential Utility of Retinal Imaging for Alzheimer’s Disease: A Review.

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Reduced axonal transport and increased excitotoxic retinal ganglion cell degeneration in mice transgenic for human mutant P301S tau.

http://www.wikidata.org/entity/Q34230291

description

2012 nî lūn-bûn

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2012 թուականի Ապրիլին հրատարակուած գիտական յօդուած

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2012 թվականի ապրիլին հրատարակված գիտական հոդված

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2012年の論文

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2012年論文

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2012年論文

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2012年論文

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2012年論文

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2012年論文

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2012年论文

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Reduced axonal transport and i ...... ic for human mutant P301S tau.

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Reduced axonal transport and i ...... ic for human mutant P301S tau.

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Reduced axonal transport and i ...... ic for human mutant P301S tau.

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Reduced axonal transport and i ...... ic for human mutant P301S tau.

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Reduced axonal transport and i ...... ic for human mutant P301S tau.

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Reduced axonal transport and i ...... ic for human mutant P301S tau.

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Reduced axonal transport and i ...... ic for human mutant P301S tau.

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Reduced axonal transport and i ...... ic for human mutant P301S tau.

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Reduced axonal transport and i ...... ic for human mutant P301S tau.

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Reduced axonal transport and i ...... ic for human mutant P301S tau.

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Alessandra Guidi

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Keith R Martin

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Maria Grazia Spillantini

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Michel Goedert

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Natalie D Bull

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P2860

Interaction of tau protein with the dynactin complex

Association of missense and 5'-splice-site mutations in tau with the inherited dementia FTDP-17

A spatial gradient of tau protein phosphorylation in nascent axons.

The amino terminus of tau inhibits kinesin-dependent axonal transport: implications for filament toxicity.

Gene therapy with brain-derived neurotrophic factor as a protection: retinal ganglion cells in a rat glaucoma model.

Axonal transport rates in vivo are unaffected by tau deletion or overexpression in mice.

Pathogenic forms of tau inhibit kinesin-dependent axonal transport through a mechanism involving activation of axonal phosphotransferases

The abnormal phosphorylation of tau protein at Ser-202 in Alzheimer disease recapitulates phosphorylation during development.

Mutation in the tau gene in familial multiple system tauopathy with presenile dementia.

A century of Alzheimer's disease.

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