Phosphatidylinositol 3-kinase signals activation of p70 S6 kinase in situ through site-specific p70 phosphorylation
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Osteopontin selectively regulates p70S6K/mTOR phosphorylation leading to NF-kappaB dependent AP-1-mediated ICAM-1 expression in breast cancer cellsCD80 and CD86 are not equivalent in their ability to induce the tyrosine phosphorylation of CD28Differential regulation of the phosphatidylinositol 3-kinase/Akt and p70 S6 kinase pathways by the alpha(1A)-adrenergic receptor in rat-1 fibroblastsClass II phosphoinositide 3-kinases are downstream targets of activated polypeptide growth factor receptorsAssociation of the insulin receptor with phospholipase C-gamma (PLCgamma) in 3T3-L1 adipocytes suggests a role for PLCgamma in metabolic signaling by insulinMultiple forms of p55PIK, a regulatory subunit of phosphoinositide 3-kinase, are generated by alternative initiation of translationNutrients suppress phosphatidylinositol 3-kinase/Akt signaling via raptor-dependent mTOR-mediated insulin receptor substrate 1 phosphorylationIRS-4 mediates protein kinase B signaling during insulin stimulation without promoting antiapoptosisDual requirement for a newly identified phosphorylation site in p70s6kCytokine-stimulated T cells induce macrophage IL-10 production dependent on phosphatidylinositol 3-kinase and p70S6K: implications for rheumatoid arthritisInsights into Aurora-A Kinase Activation Using Unnatural Amino Acids Incorporated by Chemical ModificationImmunopurified mammalian target of rapamycin phosphorylates and activates p70 S6 kinase alpha in vitroCharacterization of S6K2, a novel kinase homologous to S6K1Two motifs in the translational repressor PHAS-I required for efficient phosphorylation by mammalian target of rapamycin and for recognition by raptorDistinct regulatory mechanism for p70 S6 kinase beta from that for p70 S6 kinase alphaRegulation of an activated S6 kinase 1 variant reveals a novel mammalian target of rapamycin phosphorylation siteSyk is required for BCR-mediated activation of p90Rsk, but not p70S6k, via a mitogen-activated protein kinase-independent pathway in B cellsNuclear export of S6K1 II is regulated by protein kinase CK2 phosphorylation at Ser-17Rapamycin inhibits didemnin B-induced apoptosis in human HL-60 cells: evidence for the possible involvement of FK506-binding protein 25Regulation of the activity of MEK kinase 1 (MEKK1) by autophosphorylation within the kinase activation domainInsulin activates a p21-activated kinase in muscle cells via phosphatidylinositol 3-kinaseTwo compartments for insulin-stimulated exocytosis in 3T3-L1 adipocytes defined by endogenous ACRP30 and GLUT4Amino acid sufficiency and mTOR regulate p70 S6 kinase and eIF-4E BP1 through a common effector mechanismRheb-TOR signaling promotes protein synthesis, but not glucose or amino acid import, in DrosophilaStructural and functional analysis of pp70S6k.p70 S6 kinase is regulated by protein kinase Czeta and participates in a phosphoinositide 3-kinase-regulated signalling complexA heat-sensitive Arabidopsis thaliana kinase substitutes for human p70s6k function in vivo.Proteomic and phosphoproteomic alterations in benign, premalignant and tumor human breast epithelial cells and xenograft lesions: biomarkers of progressionThe modular phosphorylation and activation of p70s6k.A Drosophila gene structurally and functionally homologous to the mammalian 70-kDa s6 kinase gene.Stimulation of p70S6 kinase via a growth hormone-controlled phosphatidylinositol 3-kinase pathway leads to the activation of a PDE4A cyclic AMP-specific phosphodiesterase in 3T3-F442A preadipocytesStudies of partially transforming polyomavirus mutants establish a role for phosphatidylinositol 3-kinase in activation of pp70 S6 kinaseSpecific activation of p85-p110 phosphatidylinositol 3'-kinase stimulates DNA synthesis by ras- and p70 S6 kinase-dependent pathways.Lysophosphatidic acid is a major serum noncytokine survival factor for murine macrophages which acts via the phosphatidylinositol 3-kinase signaling pathway.The phosphoinositide 3-kinase pathway in human cancer: genetic alterations and therapeutic implications.Met activation is required for early cytoprotection after ischemic kidney injury.p70 S6 kinase and actin dynamics: A perspective.Activation of p70 ribosomal protein S6 kinase is an essential step in the DNA damage-dependent signaling pathway responsible for the ultraviolet B-mediated increase in interstitial collagenase (MMP-1) and stromelysin-1 (MMP-3) protein levels in humaMembrane localization of phosphatidylinositol 3-kinase is sufficient to activate multiple signal-transducing kinase pathways.Protein kinase A-dependent and -independent signaling pathways contribute to cyclic AMP-stimulated proliferation.
P2860
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P2860
Phosphatidylinositol 3-kinase signals activation of p70 S6 kinase in situ through site-specific p70 phosphorylation
description
1995 nî lūn-bûn
@nan
1995 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
1995 թվականի հունիսին հրատարակված գիտական հոդված
@hy
1995年の論文
@ja
1995年論文
@yue
1995年論文
@zh-hant
1995年論文
@zh-hk
1995年論文
@zh-mo
1995年論文
@zh-tw
1995年论文
@wuu
name
Phosphatidylinositol 3-kinase ...... e-specific p70 phosphorylation
@ast
Phosphatidylinositol 3-kinase ...... e-specific p70 phosphorylation
@en
Phosphatidylinositol 3-kinase ...... e-specific p70 phosphorylation
@nl
type
label
Phosphatidylinositol 3-kinase ...... e-specific p70 phosphorylation
@ast
Phosphatidylinositol 3-kinase ...... e-specific p70 phosphorylation
@en
Phosphatidylinositol 3-kinase ...... e-specific p70 phosphorylation
@nl
prefLabel
Phosphatidylinositol 3-kinase ...... e-specific p70 phosphorylation
@ast
Phosphatidylinositol 3-kinase ...... e-specific p70 phosphorylation
@en
Phosphatidylinositol 3-kinase ...... e-specific p70 phosphorylation
@nl
P2093
P2860
P356
P1476
Phosphatidylinositol 3-kinase ...... e-specific p70 phosphorylation
@en
P2093
L T Williams
M T Kozlowski
P2860
P304
P356
10.1073/PNAS.92.12.5744
P407
P577
1995-06-01T00:00:00Z