Insulin activates a p21-activated kinase in muscle cells via phosphatidylinositol 3-kinase
about
Phosphorylation of myosin light chain kinase by p21-activated kinase PAK2Functional interaction between c-Abl and the p21-activated protein kinase gamma-PAKDok-R plays a pivotal role in angiopoietin-1-dependent cell migration through recruitment and activation of Pak.The role of p21-activated kinases in hepatocellular carcinoma metastasisDeciphering the link between PI3K and PAK: An opportunity to target key pathways in pancreatic cancer?PAK as a therapeutic target in gastric cancerp21-activated kinase-1 signaling regulates transcription of tissue factor and tissue factor pathway inhibitorLKB1 suppresses p21-activated kinase-1 (PAK1) by phosphorylation of Thr109 in the p21-binding domainInsulin inhibits glucocorticoid-stimulated L-type 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase gene expression by activation of the c-Jun N-terminal kinase pathwayRequirement for Akt (protein kinase B) in insulin-induced activation of glycogen synthase and phosphorylation of 4E-BP1 (PHAS-1)Signaling of the p21-activated kinase (PAK1) coordinates insulin-stimulated actin remodeling and glucose uptake in skeletal muscle cells.p21-activated protein kinase gamma-PAK in pituitary secretory granules phosphorylates prolactinp38 mitogen-activated protein kinase pathway promotes skeletal muscle differentiation. Participation of the Mef2c transcription factorEvidence that 12-lipoxygenase product 12-hydroxyeicosatetraenoic acid activates p21-activated kinase.A Nck-Pak1 signaling module is required for T-cell receptor-mediated activation of NFAT, but not of JNKmiR-23b regulates cytoskeletal remodeling, motility and metastasis by directly targeting multiple transcriptsInsulin produces myogenesis in C2C12 myoblasts by induction of NF-kappaB and downregulation of AP-1 activities.Regulation of insulin signaling by the phosphatidylinositol 3,4,5-triphosphate phosphatase SKIP through the scaffolding function of Pak1Insulin signaling leading to proliferation, survival, and membrane ruffling in C2C12 myoblasts.Signaling mechanisms in skeletal muscle: acute responses and chronic adaptations to exercise.Identification of novel gene targets and functions of p21-activated kinase 1 during DNA damage by gene expression profilingInhibition or ablation of p21-activated kinase (PAK1) disrupts glucose homeostatic mechanisms in vivo.Localization of p21-activated kinase 1 (PAK1) to pinocytic vesicles and cortical actin structures in stimulated cells.p21-activated Kinases (PAKs) Mediate the Phosphorylation of PREX2 Protein to Initiate Feedback Inhibition of Rac1 GTPase.p-21-Activated kinase 1 mediates gastrin-stimulated proliferation in the colorectal mucosa via multiple signaling pathways.Putting Rac1 on the path to glucose uptake.p21-Activated kinase-1 and its role in integrated regulation of cardiac contractility.A tale of two Paks.p21-Activated kinase mediates rapid estradiol-negative feedback actions in the reproductive axis.MAPK signalling in cardiovascular health and disease: molecular mechanisms and therapeutic targets.Pak protein kinases and their role in cancer.Development of small-molecule inhibitors of the group I p21-activated kinases, emerging therapeutic targets in cancer.Role of cytochrome P450-mediated arachidonic acid metabolites in the pathogenesis of cardiac hypertrophy.p21-Activated protein kinases and their emerging roles in glucose homeostasis.Rho GTPases in insulin-stimulated glucose uptake.Molecular mechanisms for the regulation of insulin-stimulated glucose uptake by small guanosine triphosphatases in skeletal muscle and adipocytes.Analysis of small GTPase signaling pathways using p21-activated kinase mutants that selectively couple to Cdc42.Hepatic functions of GLP-1 and its based drugs: current disputes and perspectives.Synergistic regulation of Schwann cell proliferation by heregulin and forskolin.Receptor-mediated endocytosis of albumin by kidney proximal tubule cells is regulated by phosphatidylinositide 3-kinase.
P2860
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P2860
Insulin activates a p21-activated kinase in muscle cells via phosphatidylinositol 3-kinase
description
1996 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
1996 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
article publié dans la revue scientifique Journal of Biological Chemistry
@fr
artículu científicu espublizáu en 1996
@ast
im August 1996 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 1996/08/16)
@sk
vědecký článek publikovaný v roce 1996
@cs
wetenschappelijk artikel (gepubliceerd op 1996/08/16)
@nl
наукова стаття, опублікована в серпні 1996
@uk
name
Insulin activates a p21-activa ...... phosphatidylinositol 3-kinase
@ast
Insulin activates a p21-activa ...... phosphatidylinositol 3-kinase
@en
Insulin activates a p21-activa ...... phosphatidylinositol 3-kinase
@nl
type
label
Insulin activates a p21-activa ...... phosphatidylinositol 3-kinase
@ast
Insulin activates a p21-activa ...... phosphatidylinositol 3-kinase
@en
Insulin activates a p21-activa ...... phosphatidylinositol 3-kinase
@nl
prefLabel
Insulin activates a p21-activa ...... phosphatidylinositol 3-kinase
@ast
Insulin activates a p21-activa ...... phosphatidylinositol 3-kinase
@en
Insulin activates a p21-activa ...... phosphatidylinositol 3-kinase
@nl
P2093
P2860
P356
P1476
Insulin activates a p21-activa ...... phosphatidylinositol 3-kinase
@en
P2093
S. Grinstein
T. Tsakiridis
P2860
P304
19664–19667
P356
10.1074/JBC.271.33.19664
P407
P577
1996-08-16T00:00:00Z