Structure-based design of novel nonpeptide inhibitors of the Src SH2 domain:phosphotyrosine mimetics exploiting multifunctional group replacement chemistry.

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Src inhibitors in the treatment of metastatic bone disease: rationale and clinical data Teaching resources. Protein domains that interact with receptor tyrosine kinases: structural aspects.

P2860

Q34182834-20D9D2D6-02AF-486A-943B-DBE0B2966B31 Q46365696-B925B2BC-75AA-4E27-9E45-65F73F998728

P2860

Structure-based design of novel nonpeptide inhibitors of the Src SH2 domain:phosphotyrosine mimetics exploiting multifunctional group replacement chemistry.

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http://www.wikidata.org/entity/Q44781106

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2003 nî lūn-bûn

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2003年の論文

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2003年学术文章

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2003年学术文章

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2003年学术文章

@zh-cn

2003年学术文章

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2003年学术文章

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2003年学术文章

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2003年學術文章

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2003年學術文章

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name

Structure-based design of nove ...... l group replacement chemistry.

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Structure-based design of nove ...... l group replacement chemistry.

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type

Item

label

Structure-based design of nove ...... l group replacement chemistry.

@en

Structure-based design of nove ...... l group replacement chemistry.

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prefLabel

Structure-based design of nove ...... l group replacement chemistry.

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Structure-based design of nove ...... l group replacement chemistry.

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P1476

Structure-based design of nove ...... l group replacement chemistry.

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P2093

Charles J Eyermann

http://www.w3.org/2001/XMLSchema#string

Chester A Metcalf

http://www.w3.org/2001/XMLSchema#string

David C Dalgarno

http://www.w3.org/2001/XMLSchema#string

Michael G Yang

http://www.w3.org/2001/XMLSchema#string

Noriyuki Kawahata

http://www.w3.org/2001/XMLSchema#string

Raji Sundaramoorthi

http://www.w3.org/2001/XMLSchema#string

Regine S Bohacek

http://www.w3.org/2001/XMLSchema#string

Surinder Narula

http://www.w3.org/2001/XMLSchema#string

Taylor Merry

http://www.w3.org/2001/XMLSchema#string

Tomi K Sawyer

http://www.w3.org/2001/XMLSchema#string

P2860

Src family kinases in tumor progression and metastasis

Structure-based design of an osteoclast-selective, nonpeptide src homology 2 inhibitor with in vivo antiresorptive activity

A novel phosphotyrosine mimetic 4'-carboxymethyloxy-3'-phosphonophenylalanine (Cpp): exploitation in the design of nonpeptide inhibitors of pp60(Src) SH2 domain

Binding of a high affinity phosphotyrosyl peptide to the Src SH2 domain: crystal structures of the complexed and peptide-free forms

Three-dimensional structure of the tyrosine kinase c-Src

Src inhibitors: drugs for the treatment of osteoporosis, cancer or both?

Phosphoryltyrosyl mimetics in the design of peptide-based signal transduction inhibitors.

SH2 domain inhibition: a problem solved?

Src inhibitors: genomics to therapeutics.

Targeting protein kinases for bone disease: discovery and development of Src inhibitors.

P304

717-729

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P31

scholarly article

P356

10.1002/BIP.10600

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P433

http://www.w3.org/2001/XMLSchema#string

P478

http://www.w3.org/2001/XMLSchema#string

P577

2003-01-01T00:00:00Z

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P698

14991680

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Structure-based design of novel nonpeptide inhibitors of the Src SH2 domain:phosphotyrosine mimetics exploiting multifunctional group replacement chemistry.

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P2860

P2860

Structure-based design of novel nonpeptide inhibitors of the Src SH2 domain:phosphotyrosine mimetics exploiting multifunctional group replacement chemistry.

description

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type

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P1433

P1476

P2093

P2860

P304

P31

P356

P433

P478

P577

P698

P356

P1433

P1476

P2093

P2860

P304

P31

P356

P433

P478

P577

P698