Continuous activation of gp130, a signal-transducing receptor component for interleukin 6-related cytokines, causes myocardial hypertrophy in mice.
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Heart-specific activation of LTK results in cardiac hypertrophy, cardiomyocyte degeneration and gene reprogramming in transgenic miceCrystal structure of a cytokine-binding region of gp130.Self-renewal of pluripotent embryonic stem cells is mediated via activation of STAT3Targeted disruption of gp130, a common signal transducer for the interleukin 6 family of cytokines, leads to myocardial and hematological disordersJAK2/STAT3, not ERK1/2, mediates interleukin-6-induced activation of inducible nitric-oxide synthase and decrease in contractility of adult ventricular myocytesDifferential expression of TNF-alpha, IL-6, and IGF-1 by graded mechanical stress in normal rat myocardiumDownregulation of NADPH oxidase, antioxidant enzymes, and inflammatory markers in the heart of streptozotocin-induced diabetic rats by N-acetyl-L-cysteineCardiac fibroblast: the renaissance cell.Stromal Cells in Dense Collagen Promote Cardiomyocyte and Microvascular Patterning in Engineered Human Heart Tissue.Inflammatory biomarkers as predictors of heart failure in women without obstructive coronary artery disease: A report from the NHLBI-sponsored Women's Ischemia Syndrome Evaluation (WISE).Relationship of interleukin-6 with regional and global left-ventricular function in asymptomatic individuals without clinical cardiovascular disease: insights from the Multi-Ethnic Study of Atherosclerosis.Opposing effects of Jun kinase and p38 mitogen-activated protein kinases on cardiomyocyte hypertrophyCardiotrophin-1 (CT-1): a novel hypertrophic and cardioprotective agent.A histologically distinctive interstitial pneumonia induced by overexpression of the interleukin 6, transforming growth factor beta 1, or platelet-derived growth factor B geneCytokines and their receptors in cardiovascular diseases--role of gp130 signalling pathway in cardiac myocyte growth and maintenance.Interleukin 6 mediates myocardial fibrosis, concentric hypertrophy, and diastolic dysfunction in rats.Macrophage-stimulated cardiac fibroblast production of IL-6 is essential for TGF β/Smad activation and cardiac fibrosis induced by angiotensin IICardiac hypertrophy and failure: lessons learned from genetically engineered mice.Dissecting the mechanisms of left ventricular diastolic dysfunction and inflammation in peritoneal dialysis patients.The paradigm of IL-6: from basic science to medicineRegulation of cardiac angiotensin-converting enzyme and angiotensin AT1 receptor gene expression in Npr1 gene-disrupted miceConnective tissue growth factor and cardiac diastolic dysfunction: human data from the Taiwan diastolic heart failure registry and molecular basis by cellular and animal models.Immunomodulating therapy: new treatment modality in congestive heart failure.Ameliorate Effects of Li-Fu Formula on IL-6-Mediated Cardiac Hypertrophy in Hamsters Fed with a Hyper-Cholesterol DietThe lack of cardiotrophin-1 alters expression of interleukin-6 and leukemia inhibitory factor mRNA but does not impair cardiac injury response.Inflammatory markers and incident heart failure risk in older adults: the Health ABC (Health, Aging, and Body Composition) study.Hepato-protective effect of rutin via IL-6/STAT3 pathway in CCl4-induced hepatotoxicity in rats.Simvastatin prevents isoproterenol-induced cardiac hypertrophy through modulation of the JAK/STAT pathwaySignal transduction and activator of transcription (STAT) protein-dependent activation of angiotensinogen promoter: a cellular signal for hypertrophy in cardiac muscleInterleukin-6: structure-function relationships.Interleukin (IL)-6 induction of osteoclast differentiation depends on IL-6 receptors expressed on osteoblastic cells but not on osteoclast progenitorsThe function of the soluble interleukin 6 (IL-6) receptor in vivo: sensitization of human soluble IL-6 receptor transgenic mice towards IL-6 and prolongation of the plasma half-life of IL-6.The varying faces of IL-6: From cardiac protection to cardiac failure.Cardiac fibroblasts: friend or foe?Herbal Supplement Ameliorates Cardiac Hypertrophy in Rats with CCl(4)-Induced Liver CirrhosisRole of gp130-mediated signalling pathways in the heart and its impact on potential therapeutic aspectsErythropoietin and the cardiorenal syndrome: cellular mechanisms on the cardiorenal connectors.Role of mitogen-activated protein kinase pathways in multifactorial adverse cardiac remodeling associated with metabolic syndromeNovel genetically-humanized mouse model established to evaluate efficacy of therapeutic agents to human interleukin-6 receptor.α₁A-adrenergic receptors regulate cardiac hypertrophy in vivo through interleukin-6 secretion.
P2860
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P2860
Continuous activation of gp130, a signal-transducing receptor component for interleukin 6-related cytokines, causes myocardial hypertrophy in mice.
description
1995 nî lūn-bûn
@nan
1995 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
1995 թվականի մայիսին հրատարակված գիտական հոդված
@hy
1995年の論文
@ja
1995年論文
@yue
1995年論文
@zh-hant
1995年論文
@zh-hk
1995年論文
@zh-mo
1995年論文
@zh-tw
1995年论文
@wuu
name
Continuous activation of gp130 ...... yocardial hypertrophy in mice.
@ast
Continuous activation of gp130 ...... yocardial hypertrophy in mice.
@en
Continuous activation of gp130 ...... yocardial hypertrophy in mice.
@nl
type
label
Continuous activation of gp130 ...... yocardial hypertrophy in mice.
@ast
Continuous activation of gp130 ...... yocardial hypertrophy in mice.
@en
Continuous activation of gp130 ...... yocardial hypertrophy in mice.
@nl
prefLabel
Continuous activation of gp130 ...... yocardial hypertrophy in mice.
@ast
Continuous activation of gp130 ...... yocardial hypertrophy in mice.
@en
Continuous activation of gp130 ...... yocardial hypertrophy in mice.
@nl
P2093
P2860
P356
P1476
Continuous activation of gp130 ...... yocardial hypertrophy in mice.
@en
P2093
P2860
P304
P356
10.1073/PNAS.92.11.4862
P407
P577
1995-05-01T00:00:00Z