Oncogenic ras and p53 cooperate to induce cellular senescence
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CSIG inhibits PTEN translation in replicative senescenceDNA damage signaling and p53-dependent senescence after prolonged beta-interferon stimulationp53 downregulates its activating vaccinia-related kinase 1, forming a new autoregulatory loopThe miR-17-92 cluster of microRNAs confers tumorigenicity by inhibiting oncogene-induced senescenceThe polycomb group gene Bmi1 regulates antioxidant defenses in neurons by repressing p53 pro-oxidant activityp38alpha and p38gamma mediate oncogenic ras-induced senescence through differential mechanismsp19Arf suppresses growth, progression, and metastasis of Hras-driven carcinomas through p53-dependent and -independent pathwaysDisruptive chemicals, senescence and immortalityThe oncogenic RAS2(val19) mutation locks respiration, independently of PKA, in a mode prone to generate ROS.Emerging Non-Canonical Functions and Regulation by p53: p53 and Stemnessp19ras brings a new twist to the regulation of p73 by Mdm2Ral GTPase down-regulation stabilizes and reactivates p53 to inhibit malignant transformationPEA-15 is inhibited by adenovirus E1A and plays a role in ERK nuclear export and Ras-induced senescenceAblation of PRMT6 reveals a role as a negative transcriptional regulator of the p53 tumor suppressorFunctional genetic screen for genes involved in senescence: role of Tid1, a homologue of the Drosophila tumor suppressor l(2)tid, in senescence and cell survivalContact inhibition and high cell density deactivate the mammalian target of rapamycin pathway, thus suppressing the senescence programNORE1A is a Ras senescence effector that controls the apoptotic/senescent balance of p53 via HIPK2.RAB7 counteracts PI3K-driven macropinocytosis activated at early stages of melanoma developmentUrodele p53 tolerates amino acid changes found in p53 variants linked to human cancerCharacterization of the p53 response to oncogene-induced senescence.The LIM-only protein FHL2 mediates ras-induced transformation through cyclin D1 and p53 pathways.Likelihood-Based Approach to Gene Set Enrichment Analysis with a Finite Mixture ModelGeneration of cancerous neural stem cells forming glial tumor by oncogenic stimulation.Activation of extracellular signal-regulated kinase (ERK) in G2 phase delays mitotic entry through p21CIP1.Tumor suppression by p53: making cells senescent.p35 is required for CDK5 activation in cellular senescence.Deletion of p37Ing1 in mice reveals a p53-independent role for Ing1 in the suppression of cell proliferation, apoptosis, and tumorigenesis.Potential malignant transformation in the gastric mucosa of immunodeficient mice with persistent Mycoplasma penetrans infection.Manganese superoxide dismutase induces p53-dependent senescence in colorectal cancer cells.Cellular senescence and protein degradation: breaking down cancerARF-induced downregulation of Mip130/LIN-9 protein levels mediates a positive feedback that leads to increased expression of p16Ink4a and p19Arf.Paradoxical suppression of cellular senescence by p53Caveolin-1 is required for kinase suppressor of Ras 1 (KSR1)-mediated extracellular signal-regulated kinase 1/2 activation, H-RasV12-induced senescence, and transformationTAp63 induces senescence and suppresses tumorigenesis in vivo.Promotion of direct reprogramming by transformation-deficient Myc.The PML domain of PML-RARα blocks senescence to promote leukemiaBmi1 is down-regulated in the aging brain and displays antioxidant and protective activities in neuronsThe molecular scaffold kinase suppressor of Ras 1 is a modifier of RasV12-induced and replicative senescenceCellular redox imbalance and changes of protein S-glutathionylation patterns are associated with senescence induced by oncogenic H-rasActivation of the anaphase promoting complex by HTLV-1 tax leads to senescence.
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P2860
Oncogenic ras and p53 cooperate to induce cellular senescence
description
2002 nî lūn-bûn
@nan
2002 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
name
Oncogenic ras and p53 cooperate to induce cellular senescence
@ast
Oncogenic ras and p53 cooperate to induce cellular senescence
@en
Oncogenic ras and p53 cooperate to induce cellular senescence
@nl
type
label
Oncogenic ras and p53 cooperate to induce cellular senescence
@ast
Oncogenic ras and p53 cooperate to induce cellular senescence
@en
Oncogenic ras and p53 cooperate to induce cellular senescence
@nl
prefLabel
Oncogenic ras and p53 cooperate to induce cellular senescence
@ast
Oncogenic ras and p53 cooperate to induce cellular senescence
@en
Oncogenic ras and p53 cooperate to induce cellular senescence
@nl
P2093
P2860
P1476
Oncogenic ras and p53 cooperate to induce cellular senescence
@en
P2093
Athena W Lin
Emmanuelle Querido
Gerardo Ferbeyre
Mila E McCurrach
Scott W Lowe
P2860
P304
P356
10.1128/MCB.22.10.3497-3508.2002
P407
P577
2002-05-01T00:00:00Z