An analog of the natural steroidal alkaloid cortistatin A potently suppresses Tat-dependent HIV transcription. - Wikidata - wikimedia - TriplyDB

An analog of the natural steroidal alkaloid cortistatin A potently suppresses Tat-dependent HIV transcription.

An analog of the natural steroidal alkaloid cortistatin A potently suppresses Tat-dependent HIV transcription.

http://www.wikidata.org/entity/Q34289422

about

Interaction between Tat and Drugs of Abuse during HIV-1 Infection and Central Nervous System Disease The cross-talk of HIV-1 Tat and methamphetamine in HIV-associated neurocognitive disorders HIV-1 functional cure: will the dream come true?Ebselen, a Small-Molecule Capsid Inhibitor of HIV-1 Replication.Targeting the Brain Reservoirs: Toward an HIV Cure Retroviral integration: Site matters: Mechanisms and consequences of retroviral integration site selection Conditional Tat protein brain expression in the GT-tg bigenic mouse induces cerebral fractional anisotropy abnormalities.The basic domain of HIV-tat transactivating protein is essential for its targeting to lipid rafts and regulating fibroblast growth factor-2 signaling in podocytes isolated from children with HIV-1-associated nephropathy.Marine sponge derived natural products between 2001 and 2010: trends and opportunities for discovery of bioactives Translational synthetic chemistry.Didehydro-cortistatin A inhibits HIV-1 Tat mediated neuroinflammation and prevents potentiation of cocaine reward in Tat transgenic mice The Tat Inhibitor Didehydro-Cortistatin A Prevents HIV-1 Reactivation from Latency.An Ounce of Tat Prevention Is Worth a Pound of Functional Cure.Targeting human respiratory syncytial virus transcription anti-termination factor M2-1 to inhibit in vivo viral replication.Tissue reservoirs of HIV Effects of conditional central expression of HIV-1 tat protein to potentiate cocaine-mediated psychostimulation and reward among male mice.Strategies to Block HIV Transcription: Focus on Small Molecule Tat Inhibitors.Targeting HIV transcription: the quest for a functional cure.Therapeutic Potential of Steroidal Alkaloids in Cancer and Other Diseases.Role of Host Factors on the Regulation of Tat-Mediated HIV-1 Transcription.Cell-Permeable Peptides Containing Cycloalanine Residues.Synthesis of the Cortistatin Pentacyclic Core by Alkoxide-Directed Metallacycle-Mediated Annulative Cross-Coupling.Didehydro-Cortistatin A: a new player in HIV-therapy?HIV-1 Eradication: Early Trials (and Tribulations).Type I interferon responses are impaired in latently HIV infected cells.Recent advances in the identification of Tat-mediated transactivation inhibitors: progressing toward a functional cure of HIV.Screening of an FDA-approved compound library identifies levosimendan as a novel anti-HIV-1 agent that inhibits viral transcription.Fate-Regulating Circuits in Viruses: From Discovery to New Therapy Targets.Rhodiola inhibits dengue virus multiplication by inducing innate immune response genes RIG-I, MDA5 and ISG in human monocytes.HIV-1 Rev downregulates Tat expression and viral replication via modulation of NAD(P)H:quinine oxidoreductase 1 (NQO1).In Vivo Suppression of HIV Rebound by Didehydro-Cortistatin A, a "Block-and-Lock" Strategy for HIV-1 Treatment.Curaxin CBL0100 Blocks HIV-1 Replication and Reactivation through Inhibition of Viral Transcriptional Elongation.Epigenetic regulation of HIV-1 latency: focus on polycomb group (PcG) proteins.Novel Latency Reversal Agents for HIV-1 Cure.Splicing Factor 3B Subunit 1 Interacts with HIV Tat and Plays a Role in Viral Transcription and Reactivation from Latency HIV-1 intron-containing RNA expression induces innate immune activation and T cell dysfunction Potent suppression of HIV-1 cell attachment by Kudzu root extract

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P2860

An analog of the natural steroidal alkaloid cortistatin A potently suppresses Tat-dependent HIV transcription.

http://www.wikidata.org/entity/Q34289422

description

2012 nî lūn-bûn

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2012 թուականի Յուլիսին հրատարակուած գիտական յօդուած

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2012 թվականի հուլիսին հրատարակված գիտական հոդված

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2012年の論文

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2012年学术文章

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2012年学术文章

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2012年学术文章

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2012年学术文章

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2012年学术文章

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2012年學術文章

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name

An analog of the natural stero ...... t-dependent HIV transcription.

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An analog of the natural stero ...... t-dependent HIV transcription.

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An analog of the natural stero ...... t-dependent HIV transcription.

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type

label

An analog of the natural stero ...... t-dependent HIV transcription.

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An analog of the natural stero ...... t-dependent HIV transcription.

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An analog of the natural stero ...... t-dependent HIV transcription.

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prefLabel

An analog of the natural stero ...... t-dependent HIV transcription.

@ast

An analog of the natural stero ...... t-dependent HIV transcription.

@en

An analog of the natural stero ...... t-dependent HIV transcription.

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J.CHOM.2012.05.016

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Cell Host & Microbe

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An analog of the natural stero ...... t-dependent HIV transcription.

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Guillaume Mousseau

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Jun Shi

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Mark A Clementz

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Michael Cameron

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Nisha Nagarsheth

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Phil Baran

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Rémi Fromentin

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Susana T Valente

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Wendy N Bakeman

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P2860

HIV-1 tat transactivator recruits p300 and CREB-binding protein histone acetyltransferases to the viral promoter

cDNA cloning and sequencing of human fibrillarin, a conserved nucleolar protein recognized by autoimmune antisera

Identification of multiple cyclin subunits of human P-TEFb

The PITSLRE/CDK11p58 protein kinase promotes centrosome maturation and bipolar spindle formation

Absolute dependence on kappa B responsive elements for initiation and Tat-mediated amplification of HIV transcription in blood CD4 T lymphocytes

Identification of a reservoir for HIV-1 in patients on highly active antiretroviral therapy

Controlling the elongation phase of transcription with P-TEFb

A novel CDK9-associated C-type cyclin interacts directly with HIV-1 Tat and mediates its high-affinity, loop-specific binding to TAR RNA

Activation of integrated provirus requires histone acetyltransferase. p300 and P/CAF are coactivators for HIV-1 Tat

P-TEFb kinase is required for HIV Tat transcriptional activation in vivo and in vitro

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97-108

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10.1016/J.CHOM.2012.05.016

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1

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12

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Nicolas Chomont

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2012-07-01T00:00:00Z

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229434282

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