Identification of a transcriptional silencer in the 5'-flanking region of the human epsilon-globin gene.
about
Characterization of the human 5-lipoxygenase gene promoterHemoglobin switching in man and chicken is mediated by a heteromeric complex between the ubiquitous transcription factor CP2 and a developmentally specific proteinCloning of the complete gene for carcinoembryonic antigen: analysis of its promoter indicates a region conveying cell type-specific expressionA negative cis-element regulates the level of enhancement by hypersensitive site 2 of the beta-globin locus control region.Phylogenetic footprinting reveals a nuclear protein which binds to silencer sequences in the human gamma and epsilon globin genesInvestigations of a human embryonic globin gene silencing element using YAC transgenic mice.Transforming growth factor-β1 induces expression of human coagulation factor XII via Smad3 and JNK signaling pathways in human lung fibroblasts.Evaluation of regulatory potential and conservation scores for detecting cis-regulatory modules in aligned mammalian genome sequences.Erythroid-specific activity of the glycophorin B promoter requires GATA-1 mediated displacement of a repressorHigh affinity YY1 binding motifs: identification of two core types (ACAT and CCAT) and distribution of potential binding sites within the human beta globin cluster.Binding of a nuclear protein to the rat growth hormone silencer elementMultiple positive and negative elements regulate human brain creatine kinase gene expressionMutation of gene-proximal regulatory elements disrupts human epsilon-, gamma-, and beta-globin expression in yeast artificial chromosome transgenic miceBinary transgenic mouse model for studying the trans control of globin gene switching: evidence that GATA-1 is an in vivo repressor of human epsilon gene expressionPhylogenetic footprinting reveals unexpected complexity in trans factor binding upstream from the epsilon-globin gene.A DNA-bending protein interacts with an essential upstream regulatory element of the human embryonic beta-like globin geneEssential role of NF-E2 in remodeling of chromatin structure and transcriptional activation of the epsilon-globin gene in vivo by 5' hypersensitive site 2 of the beta-globin locus control regionThe Drosophila dorsal morphogen represses the tolloid gene by interacting with a silencer element.The functional domains of the murine Thy-1 gene promoter.Transcriptional role of a conserved GATA-1 site in the human epsilon-globin gene promoterIdentification of positive and negative regulatory regions controlling expression of the cartilage matrix protein gene.Correlation between patterns of DNase I-hypersensitive sites and upstream promoter activity of the human epsilon-globin gene at different stages of erythroid developmentNegative regulation of the human epsilon-globin gene by transcriptional interference: role of an Alu repetitive element.A position-dependent silencer plays a major role in repressing alpha-fetoprotein expression in human hepatoma.Developmental regulation of the human embryonic beta-like globin gene is mediated by synergistic interactions among multiple tissue- and stage-specific elementsLeukotriene biosynthesis.Modifications of RNA processing modulate the expression of hemoglobin genesGATA1 and YY1 are developmental repressors of the human epsilon-globin gene.Silencing of Agamma-globin gene expression during adult definitive erythropoiesis mediated by GATA-1-FOG-1-Mi2 complex binding at the -566 GATA site.Multiple silencer elements are involved in regulating the chicken vimentin geneDistinct negative regulation of the human embryonic globin genes zeta and epsilon.A 3'-flanking NF-kappaB site mediates developmental silencing of the human zeta-globin gene.Interaction of basal positive and negative transcription elements controls repression of the proximal rat prolactin promoter in nonpituitary cells.The 5'-flanking cis-acting elements of the human epsilon-globin gene associates with the nuclear matrix and binds to the nuclear matrix proteins.Regulation of a human cytomegalovirus immediate-early gene (US3) by a silencer-enhancer combination.Intronic and flanking sequences are required to silence enhancement of an embryonic beta-type globin gene.Tissue-specific regulation of the rabbit 15-lipoxygenase gene in erythroid cells by a transcriptional silencer.Adult chicken alpha-globin gene expression in transfected QT6 quail cells: evidence for a negative regulatory element in the alpha D gene regionDevelopmentally regulated and erythroid-specific expression of the human embryonic beta-globin gene in transgenic miceA proximal tissue-specific module and a distal negative regulatory module control apolipoprotein(a) gene transcription.
P2860
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P2860
Identification of a transcriptional silencer in the 5'-flanking region of the human epsilon-globin gene.
description
1989 nî lūn-bûn
@nan
1989 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
1989 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
1989年の論文
@ja
1989年論文
@yue
1989年論文
@zh-hant
1989年論文
@zh-hk
1989年論文
@zh-mo
1989年論文
@zh-tw
1989年论文
@wuu
name
Identification of a transcript ...... the human epsilon-globin gene.
@ast
Identification of a transcript ...... the human epsilon-globin gene.
@en
Identification of a transcript ...... the human epsilon-globin gene.
@nl
type
label
Identification of a transcript ...... the human epsilon-globin gene.
@ast
Identification of a transcript ...... the human epsilon-globin gene.
@en
Identification of a transcript ...... the human epsilon-globin gene.
@nl
prefLabel
Identification of a transcript ...... the human epsilon-globin gene.
@ast
Identification of a transcript ...... the human epsilon-globin gene.
@en
Identification of a transcript ...... the human epsilon-globin gene.
@nl
P2093
P2860
P356
P1476
Identification of a transcript ...... the human epsilon-globin gene.
@en
P2093
P2860
P304
P356
10.1073/PNAS.86.14.5306
P407
P577
1989-07-01T00:00:00Z