Type 1 insulin-like growth factor receptor translocates to the nucleus of human tumor cells.
about
Molecular basis of signaling specificity of insulin and IGF receptors: neglected corners and recent advancesNuclear IGF1R is a transcriptional co-activator of LEF1/TCFInsulin-like Growth Factor 1 Signaling Axis Meets p53 Genome Protection PathwaysThe role of endocytic Rab GTPases in regulation of growth factor signaling and the migration and invasion of tumor cellsUnderstanding the Key to Targeting the IGF Axis in Cancer: A Biomarker AssessmentReceptor tyrosine kinases in the nucleusIgf1r signaling is indispensable for preimplantation development and is activated via a novel function of E-cadherinThe tomato cell death suppressor Adi3 is restricted to the endosomal system in response to the Pseudomonas syringae effector protein AvrPtoThe insulin receptor substrate 1 (IRS1) in intestinal epithelial differentiation and in colorectal cancerInsulin/IGF and sex hormone axes in human endometrium and associations with endometrial cancer risk factors.Small is beautiful: insulin-like growth factors and their role in growth, development, and cancerA model to explain specific cellular communications and cellular harmony:- a hypothesis of coupled cells and interactive coupling molecules.Revealing molecular mechanisms by integrating high-dimensional functional screens with protein interaction data.Novel nuclear localization and potential function of insulin-like growth factor-1 receptor/insulin receptor hybrid in corneal epithelial cellsDurable Response of Spinal Chordoma to Combined Inhibition of IGF-1R and EGFRInsulin receptor expression in clear cell renal cell carcinoma and its relation to prognosis.Role of receptor tyrosine kinases and their ligands in glioblastoma.Differential subcellular and extracellular localisations of proteins required for insulin-like growth factor- and extracellular matrix-induced signalling events in breast cancer progressionThe nuclear localization of MGF receptor in osteoblasts under mechanical stimulation.Can we unlock the potential of IGF-1R inhibition in cancer therapy?Something old, something new and something borrowed: emerging paradigm of insulin-like growth factor type 1 receptor (IGF-1R) signaling regulationIGF axis and other factors in HPV-related and HPV-unrelated carcinogenesis (review).Direct recruitment of ERK cascade components to inducible genes is regulated by heterogeneous nuclear ribonucleoprotein (hnRNP) K.Expression of IGF1R in normal breast tissue and subsequent risk of breast cancerAssociation of polymorphisms and haplotypes in the insulin-like growth factor 1 receptor (IGF1R) gene with the risk of breast cancer in Korean women.The role of the insulin-like growth factor-1 system in breast cancerTransthyretin Induces Insulin-like Growth Factor I Nuclear Translocation Regulating Its Levels in the HippocampusExpression of the IGF axis is decreased in local prostate cancer but enhanced after benign prostate epithelial differentiation and TGF-β treatment.Insulin-like growth factor-I receptor (IGF-IR) translocates to nucleus and autoregulates IGF-IR gene expression in breast cancer cells.Insulin-like growth factor-1 signaling in renal cell carcinomaProteolytic cleavage, trafficking, and functions of nuclear receptor tyrosine kinases.Orai1 Expression Is Closely Related with Favorable Prognostic Factors in Clear Cell Renal Cell CarcinomaKlotho plays a critical role in clear cell renal cell carcinoma progression and clinical outcomeA kinase-independent biological activity for insulin growth factor-1 receptor (IGF-1R) : implications for inhibition of the IGF-1R signal.Insulin-like growth factor: current concepts and new developments in cancer therapy.Dynamic and nuclear expression of PDGFRα and IGF-1R in alveolar RhabdomyosarcomaNuclearly translocated insulin-like growth factor 1 receptor phosphorylates histone H3 at tyrosine 41 and induces SNAI2 expression via Brg1 chromatin remodeling protein.The emerging role of insulin and insulin-like growth factor signaling in cancer stem cells.Targeting the IGF-1R signaling and mechanisms for epigenetic gene silencing in human multiple myelomaThe decline and fall of the IGF-I receptor.
P2860
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P2860
Type 1 insulin-like growth factor receptor translocates to the nucleus of human tumor cells.
description
2010 nî lūn-bûn
@nan
2010 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Type 1 insulin-like growth fac ...... nucleus of human tumor cells.
@ast
Type 1 insulin-like growth fac ...... nucleus of human tumor cells.
@en
Type 1 insulin-like growth fac ...... nucleus of human tumor cells.
@nl
type
label
Type 1 insulin-like growth fac ...... nucleus of human tumor cells.
@ast
Type 1 insulin-like growth fac ...... nucleus of human tumor cells.
@en
Type 1 insulin-like growth fac ...... nucleus of human tumor cells.
@nl
prefLabel
Type 1 insulin-like growth fac ...... nucleus of human tumor cells.
@ast
Type 1 insulin-like growth fac ...... nucleus of human tumor cells.
@en
Type 1 insulin-like growth fac ...... nucleus of human tumor cells.
@nl
P2093
P2860
P1433
P1476
Type 1 insulin-like growth fac ...... nucleus of human tumor cells.
@en
P2093
Andrew S Protheroe
Gareth D Turner
Mark Howarth
Meenali M Chitnis
Olga V Perestenko
Peter H Thomas
Tamara Aleksic
Valentine M Macaulay
P2860
P304
P356
10.1158/0008-5472.CAN-10-0052
P407
P577
2010-08-01T00:00:00Z