Identification of c-Cbl as a new ligase for insulin-like growth factor-I receptor with distinct roles from Mdm2 in receptor ubiquitination and endocytosis
about
Molecular basis of signaling specificity of insulin and IGF receptors: neglected corners and recent advancesIdentification of the cathelicidin peptide LL-37 as agonist for the type I insulin-like growth factor receptorUpregulation of the E3 ligase NEDD4-1 by oxidative stress degrades IGF-1 receptor protein in neurodegenerationEmerging role of Lys-63 ubiquitination in protein kinase and phosphatase activation and cancer developmentNedd4 controls animal growth by regulating IGF-1 signalingNedd4 and Nedd4-2: closely related ubiquitin-protein ligases with distinct physiological functionsTemporal proteomics of NGF-TrkA signaling identifies an inhibitory role for the E3 ligase Cbl-b in neuroblastoma cell differentiationUbiquitin ligase Cbl-b represses IGF-I-induced epithelial mesenchymal transition via ZEB2 and microRNA-200c regulation in gastric cancer cellsIGF-IR internalizes with Caveolin-1 and PTRF/Cavin in HaCat cells.ErbB2 trafficking and degradation associated with K48 and K63 polyubiquitination.IGF1R signaling in Ewing sarcoma is shaped by clathrin-/caveolin-dependent endocytosis.Emerging roles of SUMO modification in arthritis.Type 1 insulin-like growth factor receptor translocates to the nucleus of human tumor cells.Something old, something new and something borrowed: emerging paradigm of insulin-like growth factor type 1 receptor (IGF-1R) signaling regulationAnalysis of the quantitative balance between insulin-like growth factor (IGF)-1 ligand, receptor, and binding protein levels to predict cell sensitivity and therapeutic efficacy.Ligand-mediated endocytosis and trafficking of the insulin-like growth factor receptor I and insulin receptor modulate receptor function.Versatile roles of k63-linked ubiquitin chains in trafficking.Regulation of Akt signaling activation by ubiquitination.Expression of IGF1R in normal breast tissue and subsequent risk of breast cancerNeuronal Cbl controls biosynthesis of insulin-like peptides in Drosophila melanogaster.Identification of calgranulin B interacting proteins and network analysis in gastrointestinal cancer cells.Synaptic proteome changes in mouse brain regions upon auditory discrimination learning.β-Arrestin-biased agonism as the central mechanism of action for insulin-like growth factor 1 receptor-targeting antibodies in Ewing's sarcoma.Endocytosis of receptor tyrosine kinasesIGF-1 receptor is down-regulated by sunitinib induces MDM2-dependent ubiquitination.Dissecting the pathways that destabilize mutant p53: the proteasome or autophagy?Dysfunction of the ubiquitin proteasome and ubiquitin-like systems in schizophrenia.Targeting SALL4 by entinostat in lung cancer.Endocytosis and signaling: cell logistics shape the eukaryotic cell plan.Distinct Temporal Regulation of RET Isoform Internalization: Roles of Clathrin and AP2.Expressions of insulin-like growth factor receptor-1 and cezanne-1 in lung adenocarcinoma.Ubc13 and COOH terminus of Hsp70-interacting protein (CHIP) are required for growth hormone receptor endocytosis.Polyubiquitination of insulin-like growth factor I receptor (IGF-IR) activation loop promotes antibody-induced receptor internalization and down-regulation.Regulation of EGFR protein stability by the HECT-type ubiquitin ligase SMURF2.Control of the dynamics and homeostasis of the Drosophila Hedgehog receptor Patched by two C2-WW-HECT-E3 Ubiquitin ligases.Unbalancing p53/Mdm2/IGF-1R axis by Mdm2 activation restrains the IGF-1-dependent invasive phenotype of skin melanoma.Functional antagonism of β-arrestin isoforms balance IGF-1R expression and signalling with distinct cancer-related biological outcomes.Quality control of plasma membrane proteins by Saccharomyces cerevisiae Nedd4-like ubiquitin ligase Rsp5p under environmental stress conditions.E3 ubiquitin ligases in cancer and implications for therapies.Receptor Tyrosine Kinase Ubiquitination and De-Ubiquitination in Signal Transduction and Receptor Trafficking.
P2860
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P2860
Identification of c-Cbl as a new ligase for insulin-like growth factor-I receptor with distinct roles from Mdm2 in receptor ubiquitination and endocytosis
description
2008 nî lūn-bûn
@nan
2008 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
Identification of c-Cbl as a n ...... ubiquitination and endocytosis
@ast
Identification of c-Cbl as a n ...... ubiquitination and endocytosis
@en
Identification of c-Cbl as a n ...... ubiquitination and endocytosis
@nl
type
label
Identification of c-Cbl as a n ...... ubiquitination and endocytosis
@ast
Identification of c-Cbl as a n ...... ubiquitination and endocytosis
@en
Identification of c-Cbl as a n ...... ubiquitination and endocytosis
@nl
prefLabel
Identification of c-Cbl as a n ...... ubiquitination and endocytosis
@ast
Identification of c-Cbl as a n ...... ubiquitination and endocytosis
@en
Identification of c-Cbl as a n ...... ubiquitination and endocytosis
@nl
P2093
P921
P1433
P1476
Identification of c-Cbl as a n ...... ubiquitination and endocytosis
@en
P2093
Bita Sehat
Olle Larsson
Sandra Andersson
P304
P356
10.1158/0008-5472.CAN-07-6364
P407
P577
2008-07-01T00:00:00Z