Genomic and proteomic analysis reveals a threshold level of MYC required for tumor maintenance. - Wikidata - wikimedia - TriplyDB

Genomic and proteomic analysis reveals a threshold level of MYC required for tumor maintenance.

Genomic and proteomic analysis reveals a threshold level of MYC required for tumor maintenance.

http://www.wikidata.org/entity/Q34314752

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Myc protein is stabilized by suppression of a novel E3 ligase complex in cancer cells Integrated network analysis of transcriptomic and proteomic data in psoriasis An atlas of combinatorial transcriptional regulation in mouse and man MYC activation is a hallmark of cancer initiation and maintenance MYC on the path to cancer Survival and death signals can predict tumor response to therapy after oncogene inactivation c-Myc is required for maintenance of glioma cancer stem cells.PrognoScan: a new database for meta-analysis of the prognostic value of genes.c-MYC-Making Liver Sick: Role of c-MYC in Hepatic Cell Function, Homeostasis and Disease.Upregulation of c-MYC in cis through a large chromatin loop linked to a cancer risk-associated single-nucleotide polymorphism in colorectal cancer cells Inactivation of MYC reverses tumorigenesis.Functional interactions between retinoblastoma and c-MYC in a mouse model of hepatocellular carcinoma.p27Kip1 mediates addiction of ovarian cancer cells to MYCC (c-MYC) and their dependence on MYC paralogs.Targeting MYC Expression through G-Quadruplexes.MYC activates stem-like cell potential in hepatocarcinoma by a p53-dependent mechanism.Myc Regulation of mRNA Cap Methylation Demonstration that drug-targeted down-regulation of MYC in non-Hodgkins lymphoma is directly mediated through the promoter G-quadruplex.Steroid Receptor Coactivator 1 Promotes Human Hepatocellular Carcinoma Progression by Enhancing Wnt/β-Catenin Signaling.The ALK(F1174L) mutation potentiates the oncogenic activity of MYCN in neuroblastoma Notching up MYC gives a LIC.Enhanced clonogenic survival induced by protein tyrosine phosphatase (PTP) inhibition after Cr(VI) exposure is mediated by c-Raf and Ras activity.Cellular MYCro economics: Balancing MYC function with MYC expression.EGFR signals downregulate tumor suppressors miR-143 and miR-145 in Western diet-promoted murine colon cancer: role of G1 regulators Cystatin D is a candidate tumor suppressor gene induced by vitamin D in human colon cancer cells.A pluripotency signature predicts histologic transformation and influences survival in follicular lymphoma patients.Nucleic acid clamp-mediated recognition and stabilization of the physiologically relevant MYC promoter G-quadruplex.Identifying regulatory mechanisms underlying tumorigenesis using locus expression signature analysis.c-Myc induction of programmed cell death may contribute to carcinogenesis: a perspective inspired by several concepts of chemical carcinogenesis.c-Myc and Her2 cooperate to drive a stem-like phenotype with poor prognosis in breast cancer.In vivo imaging-based mathematical modeling techniques that enhance the understanding of oncogene addiction in relation to tumor growth.Definition of an enhanced immune cell therapy in mice that can target stem-like lymphoma cells.Adenovirus E1A TRRAP-targeting domain-mediated enhancement of MYC association with the NuA4 complex activates a panel of MYC target genes enriched for gene expression and ribosome biogenesis.Targeting MYC-Regulated miRNAs to Combat Cancer.c-Myc deregulation induces mRNA capping enzyme dependency.Retinoblastoma has properties of a cone precursor tumor and depends upon cone-specific MDM2 signaling.DNMT3B overexpression contributes to aberrant DNA methylation and MYC-driven tumor maintenance in T-ALL and Burkitt's lymphoma.Enhanced MYC association with the NuA4 histone acetyltransferase complex mediated by the adenovirus E1A N-terminal domain activates a subset of MYC target genes highly expressed in cancer cells.Mathematical modeling of disease dynamics in SDHB- and SDHD-related paraganglioma: Further step in understanding hereditary tumor differences and future therapeutic strategies Site-specific amino acid substitution in dodecameric peptides determines the stability and unfolding of c-MYC quadruplex promoting apoptosis in cancer cells Mammalian MYC Proteins and Cancer

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Genomic and proteomic analysis reveals a threshold level of MYC required for tumor maintenance.

http://www.wikidata.org/entity/Q34314752

description

2008 nî lūn-bûn

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2008 թուականի Յուլիսին հրատարակուած գիտական յօդուած

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2008年の論文

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2008年論文

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Genomic and proteomic analysis ...... equired for tumor maintenance.

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Genomic and proteomic analysis ...... equired for tumor maintenance.

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Genomic and proteomic analysis ...... equired for tumor maintenance.

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type

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Genomic and proteomic analysis ...... equired for tumor maintenance.

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Genomic and proteomic analysis ...... equired for tumor maintenance.

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Genomic and proteomic analysis ...... equired for tumor maintenance.

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Genomic and proteomic analysis ...... equired for tumor maintenance.

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Genomic and proteomic analysis ...... equired for tumor maintenance.

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Genomic and proteomic analysis ...... equired for tumor maintenance.

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0008-5472.CAN-07-6192

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Cancer Research

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Genomic and proteomic analysis ...... equired for tumor maintenance.

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Andrew J Gentles

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Catherine M Shachaf

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Dean W Felsher

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Debashis Sahoo

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Dennis Mitchel

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Garry P Nolan

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Maria Chang

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Omar D Perez

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Orr Sharpe

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Sailaja Elchuri

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P2860

A global transcriptional regulatory role for c-Myc in Burkitt's lymphoma cells

Significance analysis of microarrays applied to the ionizing radiation response

Genomic targets of the human c-Myc protein

Global mapping of c-Myc binding sites and target gene networks in human B cells

An integrated database of genes responsive to the Myc oncogenic transcription factor: identification of direct genomic targets

Brief inactivation of c-Myc is not sufficient for sustained regression of c-Myc-induced tumours of pancreatic islets and skin epidermis

c-Myc binds to human ribosomal DNA and stimulates transcription of rRNA genes by RNA polymerase I

Characterization of the c-MYC-regulated transcriptome by SAGE: identification and analysis of c-MYC target genes

Extracting binary signals from microarray time-course data.

c-MYC induces mammary tumorigenesis by means of a preferred pathway involving spontaneous Kras2 mutations.

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5132-5142

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10.1158/0008-5472.CAN-07-6192

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