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NetWalker: a contextual network analysis tool for functional genomics

NetWalker: a contextual network analysis tool for functional genomics

http://www.wikidata.org/entity/Q34316790

about

Network-Based Protein Biomarker Discovery Platforms Integrative approaches for finding modular structure in biological networks Role of Increased n-acetylaspartate Levels in Cancer.Integration of transcriptomic and genomic data suggests candidate mechanisms for APOE4-mediated pathogenic action in Alzheimer's disease.Biologic effects of platelet-derived growth factor receptor α blockade in uterine cancer.On the performance of de novo pathway enrichment.Notch3 pathway alterations in ovarian cancer.Hematogenous metastasis of ovarian cancer: rethinking mode of spread.Definition of PKC-α, CDK6, and MET as therapeutic targets in triple-negative breast cancer Quantification of biological network perturbations for mechanistic insight and diagnostics using two-layer causal models.Loss of PPARγ expression in mammary secretory epithelial cells creates a pro-breast tumorigenic environment.Myeloid malignancies with chromosome 5q deletions acquire a dependency on an intrachromosomal NF-κB gene network The Hippo Pathway Kinases LATS1/2 Suppress Cancer Immunity Assessment of subnetwork detection methods for breast cancer Copy number gain of hsa-miR-569 at 3q26.2 leads to loss of TP53INP1 and aggressiveness of epithelial cancers.Using random walks to identify cancer-associated modules in expression data Multifaceted activities of type I interferon are revealed by a receptor antagonist.The central role of AMP-kinase and energy homeostasis impairment in Alzheimer's disease: a multifactor network analysis Gaining insights into the codon usage patterns of TP53 gene across eight mammalian species Prediction of signaling cross-talks contributing to acquired drug resistance in breast cancer cells by Bayesian statistical modeling A new strategy to ERADicate HER2-positive breast tumors?Robust Selection Algorithm (RSA) for Multi-Omic Biomarker Discovery; Integration with Functional Network Analysis to Identify miRNA Regulated Pathways in Multiple Cancers.Directed random walks and constraint programming reveal active pathways in hepatocyte growth factor signaling.miR-137 Targets p160 Steroid Receptor Coactivators SRC1, SRC2, and SRC3 and Inhibits Cell Proliferation.Systems biology approaches to study the molecular effects of caloric restriction and polyphenols on aging processes.An integrated network platform for contextual prioritization of drugs and pathways A miR-192-EGR1-HOXB9 regulatory network controls the angiogenic switch in cancer.Identification of ovarian cancer subtype-specific network modules and candidate drivers through an integrative genomics approach.Sexual Dimorphism and Aging in the Human Hyppocampus: Identification, Validation, and Impact of Differentially Expressed Genes by Factorial Microarray and Network Analysis.The long noncoding RNA Chaer defines an epigenetic checkpoint in cardiac hypertrophy.Systematic identification of molecular subtype-selective vulnerabilities in non-small-cell lung cancer Computation as the mechanistic bridge between precision medicine and systems therapeutics.Graphite Web: Web tool for gene set analysis exploiting pathway topology.Targeting KRas-dependent tumour growth, circulating tumour cells and metastasis in vivo by clinically significant miR-193a-3p Protein kinase C inhibitors sensitize GNAQ mutant uveal melanoma cells to ionizing radiation.IRAK1 is a novel DEK transcriptional target and is essential for head and neck cancer cell survival.Logic programming reveals alteration of key transcription factors in multiple myeloma.A calcium- and calpain-dependent pathway determines the response to lenalidomide in myelodysplastic syndromes ABC gene expression profiles have clinical importance and possibly form a new hallmark of cancer.Fine Tuning of a Type 1 Interferon Antagonist.

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NetWalker: a contextual network analysis tool for functional genomics

http://www.wikidata.org/entity/Q34316790

description

2012 nî lūn-bûn

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2012 թուականի Յունիսին հրատարակուած գիտական յօդուած

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2012 թվականի հունիսին հրատարակված գիտական հոդված

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2012年の論文

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NetWalker: a contextual network analysis tool for functional genomics

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Kakajan Komurov

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Serkan Dursun

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P2860

Use of data-biased random walks on graphs for the retrieval of context-specific networks from genomic data

BiGG: a Biochemical Genetic and Genomic knowledgebase of large scale metabolic reconstructions

Gene ontology: tool for the unification of biology

KEGG: kyoto encyclopedia of genes and genomes

Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles.

Pathway Commons, a web resource for biological pathway data

GAGE: generally applicable gene set enrichment for pathway analysis

HMDB: a knowledgebase for the human metabolome

MINT: the Molecular INTeraction database

Osprey: a network visualization system

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