about
Use of data-biased random walks on graphs for the retrieval of context-specific networks from genomic dataExpression of Q227L-galphas in MCF-7 human breast cancer cells inhibits tumorigenesisFormation of regulatory patterns during signal propagation in a Mammalian cellular networkSilencing of p130cas in ovarian carcinoma: a novel mechanism for tumor cell deathBioinformatics and systems biologyG protein pathways.The signaling petri net-based simulator: a non-parametric strategy for characterizing the dynamics of cell-specific signaling networksMetabolic shifts toward glutamine regulate tumor growth, invasion and bioenergetics in ovarian cancerTumor microenvironment derived exosomes pleiotropically modulate cancer cell metabolismClinical activity and safety of combination therapy with temsirolimus and bevacizumab for advanced melanoma: a phase II trial (CTEP 7190/Mel47)Rapidly exploring structural and dynamic properties of signaling networks using PathwayOracle.Biologic effects of platelet-derived growth factor receptor α blockade in uterine cancer.Targeting SRC in mucinous ovarian carcinoma.A switch in the source of ATP production and a loss in capacity to perform glycolysis are hallmarks of hepatocyte failure in advance liver disease.Notch3 pathway alterations in ovarian cancer.Stat3-mediated transformation of NIH-3T3 cells by the constitutively active Q205L Galphao protein.Genome-wide perturbations by miRNAs map onto functional cellular pathways, identifying regulators of chromatin modifiersA pan-cancer proteomic perspective on The Cancer Genome Atlas.2'-OMe-phosphorodithioate-modified siRNAs show increased loading into the RISC complex and enhanced anti-tumour activity.Core epithelial-to-mesenchymal transition interactome gene-expression signature is associated with claudin-low and metaplastic breast cancer subtypesIdentification of optimal drug combinations targeting cellular networks: integrating phospho-proteomics and computational network analysisMAP kinase phosphatase as a locus of flexibility in a mitogen-activated protein kinase signaling network.NetWalker: a contextual network analysis tool for functional genomicsCupid: simultaneous reconstruction of microRNA-target and ceRNA networks.Copy number gain of hsa-miR-569 at 3q26.2 leads to loss of TP53INP1 and aggressiveness of epithelial cancers.Immunotherapy targeting folate receptor induces cell death associated with autophagy in ovarian cancer.Mapping network motif tunability and robustness in the design of synthetic signaling circuits.Functional proteomics identifies miRNAs to target a p27/Myc/phospho-Rb signature in breast and ovarian cancer.Robust Selection Algorithm (RSA) for Multi-Omic Biomarker Discovery; Integration with Functional Network Analysis to Identify miRNA Regulated Pathways in Multiple Cancers.The glucose-deprivation network counteracts lapatinib-induced toxicity in resistant ErbB2-positive breast cancer cellsExpression patterns of novel genes during mouse preimplantation embryogenesis.Adrenergic Stimulation of DUSP1 Impairs Chemotherapy Response in Ovarian Cancer.A miR-192-EGR1-HOXB9 regulatory network controls the angiogenic switch in cancer.Direct Upregulation of STAT3 by MicroRNA-551b-3p Deregulates Growth and Metastasis of Ovarian Cancer.Tumour angiogenesis regulation by the miR-200 family.Platelet-derived growth factor receptor alpha (PDGFRα) targeting and relevant biomarkers in ovarian carcinoma.Targeting KRas-dependent tumour growth, circulating tumour cells and metastasis in vivo by clinically significant miR-193a-3pNetwork Motifs in JNK Signaling.Cancer Systems Biology: a peek into the future of patient care?Kinome siRNA-phosphoproteomic screen identifies networks regulating AKT signaling
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description
researcher
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wetenschapper
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հետազոտող
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Prahlad T. Ram
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Prahlad T. Ram
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Prahlad T. Ram
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Prahlad T. Ram
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Prahlad T. Ram
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Prahlad T. Ram
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Prahlad T. Ram
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Prahlad T. Ram
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Prahlad T. Ram
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Prahlad T. Ram
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Prahlad T. Ram
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Prahlad T. Ram
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Prahlad T. Ram
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Prahlad T. Ram
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Prahlad T. Ram
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P106
P1153
7007153993
P2456
P31
P496
0000-0003-4739-3166