A novel beta subunit increases rate of inactivation of specific voltage-gated potassium channel alpha subunits.
about
Coexpression of the KCNA3B gene product with Kv1.5 leads to a novel A-type potassium channelp11, an annexin II subunit, an auxiliary protein associated with the background K+ channel, TASK-1Molecular cloning, expression and catalytic activity of a human AKR7 member of the aldo-keto reductase superfamily: evidence that the major 2-carboxybenzaldehyde reductase from human liver is a homologue of rat aflatoxin B1-aldehyde reductaseCloning, expression, and distribution of a Ca(2+)-activated K+ channel beta-subunit from human brainAlternative splicing of the human Shaker K+ channel beta 1 gene and functional expression of the beta 2 gene productCharacterization of a voltage-gated K+ channel beta subunit expressed in human heartThe beta subunit increases the Ca2+ sensitivity of large conductance Ca2+-activated potassium channels by retaining the gating in the bursting statesInactivation of BK channels mediated by the NH(2) terminus of the beta3b auxiliary subunit involves a two-step mechanism: possible separation of binding and blockadeSelective interaction of voltage-gated K+ channel beta-subunits with alpha-subunitsVoltage-dependent K+ channel beta subunits in muscle: differential regulation during postnatal development and myogenesisSeparable effects of human Kvbeta1.2 N- and C-termini on inactivation and expression of human Kv1.4KChAP as a chaperone for specific K(+) channelsStructure-activity relationships of the Kvbeta1 inactivation domain and its putative receptor probed using peptide analogs of voltage-gated potassium channel alpha- and beta-subunits.Regulation of voltage-gated K+ channel expression in the developing mammalian myocardium.Modulation of voltage-dependent Shaker family potassium channels by an aldo-keto reductase.Structural basis for the biological activity of dendrotoxin-I, a potent potassium channel blocker.The cytosolic inactivation domains of BKi channels in rat chromaffin cells do not behave like simple, open-channel blockersMolecular basis of functional voltage-gated K+ channel diversity in the mammalian myocardium.In vivo functional role of the Drosophila hyperkinetic beta subunit in gating and inactivation of Shaker K+ channels.Inactivating BK channels in rat chromaffin cells may arise from heteromultimeric assembly of distinct inactivation-competent and noninactivating subunits.Molecular basis of hypoxia-induced pulmonary vasoconstriction: role of voltage-gated K+ channels.Assembly of voltage-gated potassium channels. Conserved hydrophilic motifs determine subfamily-specific interactions between the alpha-subunits.A model of the interaction between N-type and C-type inactivation in Kv1.4 channels.Oxidation of NADPH on Kvbeta1 inhibits ball-and-chain type inactivation by restraining the chain.Distinct functional stoichiometry of potassium channel beta subunitsLong QT and ventricular arrhythmias in transgenic mice expressing the N terminus and first transmembrane segment of a voltage-gated potassium channel.Transient outward potassium current, 'Ito', phenotypes in the mammalian left ventricle: underlying molecular, cellular and biophysical mechanisms.Distinct transient outward potassium current (Ito) phenotypes and distribution of fast-inactivating potassium channel alpha subunits in ferret left ventricular myocytesDevelopmental analysis reveals mismatches in the expression of K+ channel alpha subunits and voltage-gated K+ channel currents in rat ventricular myocytes.Molecular and functional characterization of a rat brain Kv beta 3 potassium channel subunit.Modification of K+ channel-drug interactions by ancillary subunits.The N-terminal domain of a K+ channel beta subunit increases the rate of C-type inactivation from the cytoplasmic side of the channel.Overexpression of a Shaker-type potassium channel in mammalian central nervous system dysregulates native potassium channel gene expression.Synaptotagmin I delays the fast inactivation of Kv1.4 channel through interaction with its N-terminusTransient outward potassium channel: a heart failure mediator.Kvbeta2 inhibits the Kvbeta1-mediated inactivation of K+ channels in transfected mammalian cells.Beta1-subunits increase surface expression of a large-conductance Ca2+-activated K+ channel isoform.Reduced K+ channel inactivation, spike broadening, and after-hyperpolarization in Kvbeta1.1-deficient mice with impaired learning.Kvbeta1.2 subunit coexpression in HEK293 cells confers O2 sensitivity to kv4.2 but not to Shaker channels.Inactivation of a voltage-dependent K+ channel by beta subunit. Modulation by a phosphorylation-dependent interaction between the distal C terminus of alpha subunit and cytoskeleton.
P2860
Q22008555-D772E311-A4C0-471E-B047-79899FABE1FCQ24305279-3E98DDE7-35DC-435D-A01E-A734DA586008Q24313464-A00339F3-4CE0-420D-8DB9-CD718AA0ACD8Q24322785-38ADBFCC-65CB-4469-A5A2-960CC77ADF0AQ24324666-21FECED9-92FB-4606-A5D0-E64361225783Q24563816-D7FC29B4-CBF8-4227-8570-FCB6E2BCAE1EQ24642378-37FFC73A-F0E1-40BD-A3CD-C6F39026F309Q24653384-04CF0969-F7C6-419D-98E4-88A5000FEEF0Q28279423-D17D5C17-EDC3-458A-8305-EB55490FDC6EQ28568351-FC677F0E-0924-4437-B84D-33F4B65BA9C3Q28570434-A3C3B532-4A88-469E-8E4B-AB1B35CCA3E8Q28575980-B8A40ACD-25B4-482A-8CD3-B2D455170536Q31980386-94874EF2-19BC-4050-B82B-08D86BE83DDBQ31997375-2C8F71FD-589F-4C1A-938A-9699899A08A6Q33822408-3E9DDAF4-8B28-4CF0-9C20-01C326790362Q33900937-413332DE-2728-48B6-87C0-DE81BEC790FFQ33907201-3948D33D-C1D3-4F03-9B6E-0E116B75BA85Q33931559-E7A55C50-0155-441F-9B63-1FBE1919267FQ34041283-AA930927-780B-4601-882E-72899CB79142Q34167091-13E8CC34-6AC7-468C-BBE1-BEE987AE9A3EQ34280464-9AE40954-1133-4C1E-8003-95F688FEF8ABQ34295548-AB67A6DF-AEB4-44F2-88BB-25A2C576ABBEQ34439397-AA96D83A-826E-4567-BBFE-137AE173722EQ34805109-E411EC48-F7BB-4443-8851-924CFBC6BDE1Q35893525-E1E7FAA3-92AA-4DCD-9F24-3DE6390D9628Q35974594-4857170A-2133-4C90-BE0A-C83858564556Q36098638-25231B44-7110-4DB8-90EF-F6F0B6753A67Q36412110-18F29BFF-E948-440B-A14A-3F1E509ADAF0Q36435822-84E3DBD0-101F-487D-88F6-EFCCC8E66F7DQ36789876-28940FA8-8CFE-4231-B307-68A53BC09251Q37039299-E284D419-0655-4A7A-BF0B-F257514DF327Q37085420-C7D32AF0-088E-4BB9-8F8C-1C316DA0A6DDQ37187935-AB089389-94B9-41B3-A078-7B5FDAA5AEFFQ37497672-A850C091-7C25-4858-AD2A-7D6E6D327D37Q38342269-8BB4627C-AD02-4DA9-B706-428F7ABB0A9FQ38346166-200D67B2-538A-40E3-9DF9-19A8506577C5Q40165240-648E0ED0-75D0-4810-B70C-BE9414B5CECEQ40415967-C75AD415-39D0-425A-A598-0B4C167D6455Q41918102-E6D4FE36-2EA4-40B6-AE0C-73B5CE9AD00EQ42438782-BA496D96-17C8-4BAF-8B17-B56A26121F5E
P2860
A novel beta subunit increases rate of inactivation of specific voltage-gated potassium channel alpha subunits.
description
1995 nî lūn-bûn
@nan
1995 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
1995 թվականի մարտին հրատարակված գիտական հոդված
@hy
1995年の論文
@ja
1995年学术文章
@wuu
1995年学术文章
@zh-cn
1995年学术文章
@zh-hans
1995年学术文章
@zh-my
1995年学术文章
@zh-sg
1995年學術文章
@yue
name
A novel beta subunit increases ...... assium channel alpha subunits.
@ast
A novel beta subunit increases ...... assium channel alpha subunits.
@en
A novel beta subunit increases ...... assium channel alpha subunits.
@nl
type
label
A novel beta subunit increases ...... assium channel alpha subunits.
@ast
A novel beta subunit increases ...... assium channel alpha subunits.
@en
A novel beta subunit increases ...... assium channel alpha subunits.
@nl
prefLabel
A novel beta subunit increases ...... assium channel alpha subunits.
@ast
A novel beta subunit increases ...... assium channel alpha subunits.
@en
A novel beta subunit increases ...... assium channel alpha subunits.
@nl
P2093
P2860
P356
P1476
A novel beta subunit increases ...... assium channel alpha subunits.
@en
P2093
Castellino RC
Morales MJ
Rasmusson RL
Strauss HC
P2860
P304
P356
10.1074/JBC.270.11.6272
P407
P577
1995-03-01T00:00:00Z