Human longevity and 11p15.5: a study in 1321 centenarians - Wikidata - wikimedia - TriplyDB

Human longevity and 11p15.5: a study in 1321 centenarians

Human longevity and 11p15.5: a study in 1321 centenarians

http://www.wikidata.org/entity/Q34327320

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SIRT3 regulates progression and development of diseases of aging.Modulation of human longevity by SIRT3 single nucleotide polymorphisms in the prospective study "Treviso Longeva (TRELONG)".Sirtuin 3 deficiency does not alter host defenses against bacterial and fungal infections.Sirtuins: guardians of mammalian healthspan.Sirt3, mitochondrial ROS, ageing, and carcinogenesis.Mitochondrial-nuclear epistasis: implications for human aging and longevity.Genome maintenance and human longevity.Decreased SIRT3 in aged human mesenchymal stromal/stem cells increases cellular susceptibility to oxidative stress.Expansions of NK-like αβT cells with chronologic aging: novel lymphocyte effectors that compensate for functional deficits of conventional NK cells and T cells.Mitochondrial acetylation and diseases of aging.SIRT6 minor allele genotype is associated with >5-year decrease in lifespan in an aged cohort.The molecular genetics of sirtuins: association with human longevity and age-related diseases Association of TH01 with human longevity revisited.Large common deletions associate with mortality at old age.Are sirtuins viable targets for improving healthspan and lifespan?Sirtuins Function as the Modulators in Aging-related Diseases in Common or Respectively The sirtuin family's role in aging and age-associated pathologies.Evidence from case-control and longitudinal studies supports associations of genetic variation in APOE, CETP, and IL6 with human longevity.Exploring the role of genetic variability and lifestyle in oxidative stress response for healthy aging and longevity.Mitochondrial sirtuins in the regulation of mitochondrial activity and metabolic adaptation.Sirtuins: from metabolic regulation to brain aging.Sirtuins, a promising target in slowing down the ageing process.Insulin/insulin-like growth factor-1 signalling (IIS) based regulation of lifespan across species.Impact of caloric restriction on myocardial ischaemia/reperfusion injury and new therapeutic options to mimic its effects Sirtuins, bioageing, and cancer.Centenarians, but not octogenarians, up-regulate the expression of microRNAs Heritability analysis of life span in a semi-isolated population followed across four centuries reveals the presence of pleiotropy between life span and reproduction.Enhanced longevity and metabolism by brown adipose tissue with disruption of the regulator of G protein signaling 14.

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Human longevity and 11p15.5: a study in 1321 centenarians

http://www.wikidata.org/entity/Q34327320

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2009 nî lūn-bûn

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2009 թուականի Ապրիլին հրատարակուած գիտական յօդուած

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2009 թվականի ապրիլին հրատարակված գիտական հոդված

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2009年の論文

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2009年論文

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2009年論文

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2009年論文

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2009年論文

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2009年論文

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2009年论文

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Human longevity and 11p15.5: a study in 1321 centenarians

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Human longevity and 11p15.5: a study in 1321 centenarians

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Human longevity and 11p15.5: a study in 1321 centenarians

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Human longevity and 11p15.5: a study in 1321 centenarians

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Human longevity and 11p15.5: a study in 1321 centenarians

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Human longevity and 11p15.5: a study in 1321 centenarians

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Human longevity and 11p15.5: a study in 1321 centenarians

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Human longevity and 11p15.5: a study in 1321 centenarians

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European Journal of Human Genetics

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Human longevity and 11p15.5: a study in 1321 centenarians

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Eline Slagboom

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Friederike Flachsbart

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Giuseppe Passarino

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Helene Blanché

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Mourad Sahbatou

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Stefan Schreiber

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P2860

SIRT3, a human SIR2 homologue, is an NAD-dependent deacetylase localized to mitochondria

Statistical significance for genomewide studies

Meta-analysis in clinical trials

Arlequin (version 3.0): an integrated software package for population genetics data analysis

Statistical aspects of the analysis of data from retrospective studies of disease

Haploview: analysis and visualization of LD and haplotype maps

Genes, demography, and life span: the contribution of demographic data in genetic studies on aging and longevity

Multiple testing in the context of haplotype analysis revisited: application to case-control data.

A novel VNTR enhancer within the SIRT3 gene, a human homologue of SIR2, is associated with survival at oldest ages.

Calorie restriction--the SIR2 connection.

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1515-1519

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10.1038/EJHG.2009.54

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11

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17

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Claudio Franceschi

Francesco Lescai

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2009-04-15T00:00:00Z

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24278444

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19367319

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2986679

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