Increased superoxide in vivo accelerates age-associated muscle atrophy through mitochondrial dysfunction and neuromuscular junction degeneration
about
Inhibition of xanthine oxidase reduces oxidative stress and improves skeletal muscle function in response to electrically stimulated isometric contractions in aged miceBeyond Diabetes: Does Obesity-Induced Oxidative Stress Drive the Aging Process?The Role of Autophagy, Mitophagy and Lysosomal Functions in Modulating Bioenergetics and Survival in the Context of Redox and Proteotoxic Damage: Implications for Neurodegenerative DiseasesMechanisms of Muscle Denervation in Aging: Insights from a Mouse Model of Amyotrophic Lateral SclerosisThe effect of physiological stimuli on sarcopenia; impact of Notch and Wnt signaling on impaired aged skeletal muscle repairMitochondrial oxidative stress in aging and healthspanDenervation causes fiber atrophy and myosin heavy chain co-expression in senescent skeletal muscleMitochondrial structure and function are disrupted by standard isolation methodsLipid modulation of skeletal muscle mass and functionSkeletal Muscle Satellite Cells, Mitochondria, and MicroRNAs: Their Involvement in the Pathogenesis of ALSElevated hydrogen peroxide and decreased catalase and glutathione peroxidase protection are associated with aging sarcopeniaElevated protein carbonylation, and misfolding in sciatic nerve from db/db and Sod1(-/-) mice: plausible link between oxidative stress and demyelinationHaptoglobin is required to prevent oxidative stress and muscle atrophy.The lack of CuZnSOD leads to impaired neurotransmitter release, neuromuscular junction destabilization and reduced muscle strength in mice.A systematic review of the evidence that brain structure is related to muscle structure and their relationship to brain and muscle function in humans over the lifecourse.Dietary and genetic evidence for phosphate toxicity accelerating mammalian aging.Mitochondrial uncoupling and lifespan.Reduced coupling of oxidative phosphorylation in vivo precedes electron transport chain defects due to mild oxidative stress in mice.Striking denervation of neuromuscular junctions without lumbar motoneuron loss in geriatric mouse muscle.Skeletal muscle apoptotic signaling predicts thigh muscle volume and gait speed in community-dwelling older persons: an exploratory study.Superoxide dismutase 1 loss disturbs intracellular redox signaling, resulting in global age-related pathological changes.Mouse Models of Oxidative Stress Indicate a Role for Modulating Healthy Aging.SOD1 targeted to the mitochondrial intermembrane space prevents motor neuropathy in the Sod1 knockout mouse.Sarcopenia and Androgens: A Link between Pathology and Treatment.Superoxide dismutases and superoxide reductases.Granulocyte colony stimulating factor attenuates inflammation in a mouse model of amyotrophic lateral sclerosis.Muscle-derived extracellular signal-regulated kinases 1 and 2 are required for the maintenance of adult myofibers and their neuromuscular junctions.Living in a box or call of the wild? Revisiting lifetime inactivity and sarcopeniaSkeletal muscle weakness due to deficiency of CuZn-superoxide dismutase is associated with loss of functional innervationObesity-induced oxidative stress, accelerated functional decline with age and increased mortality in mice.Oxidative stress and redox regulation on hippocampal-dependent cognitive functionsThe redox stress hypothesis of agingTime-Point Dependent Activation of Autophagy and the UPS in SOD1G93A Mice Skeletal MuscleRedox regulation of muscle adaptations to contractile activity and aging.Autophagy impairment in muscle induces neuromuscular junction degeneration and precocious aging.Dietary restriction attenuates age-associated muscle atrophy by lowering oxidative stress in mice even in complete absence of CuZnSOD.Impaired adaptability of in vivo mitochondrial energetics to acute oxidative insult in aged skeletal muscledj-1β regulates oxidative stress, insulin-like signaling and development in Drosophila melanogaster.Apoptosis and necrosis mediate skeletal muscle fiber loss in age-induced mitochondrial enzymatic abnormalities.The histone deacetylase inhibitor butyrate improves metabolism and reduces muscle atrophy during aging.
P2860
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P2860
Increased superoxide in vivo accelerates age-associated muscle atrophy through mitochondrial dysfunction and neuromuscular junction degeneration
description
2009 nî lūn-bûn
@nan
2009 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
Increased superoxide in vivo a ...... muscular junction degeneration
@ast
Increased superoxide in vivo a ...... muscular junction degeneration
@en
Increased superoxide in vivo a ...... muscular junction degeneration
@nl
type
label
Increased superoxide in vivo a ...... muscular junction degeneration
@ast
Increased superoxide in vivo a ...... muscular junction degeneration
@en
Increased superoxide in vivo a ...... muscular junction degeneration
@nl
prefLabel
Increased superoxide in vivo a ...... muscular junction degeneration
@ast
Increased superoxide in vivo a ...... muscular junction degeneration
@en
Increased superoxide in vivo a ...... muscular junction degeneration
@nl
P2093
P2860
P356
P1433
P1476
Increased superoxide in vivo a ...... muscular junction degeneration
@en
P2093
Adam B Salmon
Arlan Richardson
Arunabh Bhattacharya
Christopher R Hayworth
Hanyu Liang
Lisa Larkin
Michael S Lustgarten
Susan V Brooks
Youngmok C Jang
Yuhong Liu
P2860
P304
P356
10.1096/FJ.09-146308
P407
P577
2009-12-29T00:00:00Z