Skeletal muscle weakness due to deficiency of CuZn-superoxide dismutase is associated with loss of functional innervation
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The Role of Autophagy, Mitophagy and Lysosomal Functions in Modulating Bioenergetics and Survival in the Context of Redox and Proteotoxic Damage: Implications for Neurodegenerative DiseasesParadoxical Roles of Antioxidant Enzymes: Basic Mechanisms and Health ImplicationsThe lack of CuZnSOD leads to impaired neurotransmitter release, neuromuscular junction destabilization and reduced muscle strength in mice.Differential cysteine labeling and global label-free proteomics reveals an altered metabolic state in skeletal muscle aging.Identification of proteins from interstitium of trapezius muscle in women with chronic myalgia using microdialysis in combination with proteomicsDeletion of connexin43 in osteoblasts/osteocytes leads to impaired muscle formation in mice.Engineered skeletal muscle units for repair of volumetric muscle loss in the tibialis anterior muscle of a ratRedox regulation of muscle adaptations to contractile activity and aging.Weakness of whole muscles in mice deficient in Cu, Zn superoxide dismutase is not explained by defects at the level of the contractile apparatus.Is SOD1 loss of function involved in amyotrophic lateral sclerosis?Interactions between reactive oxygen species generated by contractile activity and aging in skeletal muscle?CuZnSOD gene deletion targeted to skeletal muscle leads to loss of contractile force but does not cause muscle atrophy in adult miceNeuron specific reduction in CuZnSOD is not sufficient to initiate a full sarcopenia phenotype.Role of reactive oxygen species in the defective regeneration seen in aging muscle.Neuron-specific expression of CuZnSOD prevents the loss of muscle mass and function that occurs in homozygous CuZnSOD-knockout miceRedox homeostasis and age-related deficits in neuromuscular integrity and function.Role of reactive oxygen species in age-related neuromuscular deficits.The role of oxidative stress in nervous system aging.Role of nerve-muscle interactions and reactive oxygen species in regulation of muscle proteostasis with ageing.Denervated muscle fibers induce mitochondrial peroxide generation in neighboring innervated fibers: Role in muscle aging.Comparison of Whole Body SOD1 Knockout with Muscle-Specific SOD1 Knockout Mice Reveals a Role for Nerve Redox Signaling in Regulation of Degenerative Pathways in Skeletal Muscle.Long term rapamycin treatment improves mitochondrial DNA quality in aging mice.A new mouse model of frailty: the Cu/Zn superoxide dismutase knockout mouse.Nrf2 deficiency exacerbates age-related contractile dysfunction and loss of skeletal muscle mass.Oxidative stress-induced dysregulation of excitation-contraction coupling contributes to muscle weaknessAge-related changes in skeletal muscle: changes to life-style as a therapy
P2860
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P2860
Skeletal muscle weakness due to deficiency of CuZn-superoxide dismutase is associated with loss of functional innervation
description
2011 nî lūn-bûn
@nan
2011 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Skeletal muscle weakness due t ...... loss of functional innervation
@ast
Skeletal muscle weakness due t ...... loss of functional innervation
@en
type
label
Skeletal muscle weakness due t ...... loss of functional innervation
@ast
Skeletal muscle weakness due t ...... loss of functional innervation
@en
prefLabel
Skeletal muscle weakness due t ...... loss of functional innervation
@ast
Skeletal muscle weakness due t ...... loss of functional innervation
@en
P2093
P2860
P1476
Skeletal muscle weakness due t ...... loss of functional innervation
@en
P2093
Arlan Richardson
Carol S Davis
Catrina Sims-Robinson
Holly Van Remmen
Lisa M Larkin
Tatiana Y Kostrominova
P2860
P304
P356
10.1152/AJPREGU.00093.2011
P577
2011-09-07T00:00:00Z