Evidence that the COOH terminus of human presenilin 1 is located in extracytoplasmic space.
about
Presenilin-1 maintains a nine-transmembrane topology throughout the secretory pathwayAssembly, trafficking and function of gamma-secretasePen-2 is incorporated into the gamma-secretase complex through binding to transmembrane domain 4 of presenilin 1Peptides of presenilin-1 bind the amyloid precursor protein ectodomain and offer a novel and specific therapeutic approach to reduce ß-amyloid in Alzheimer's diseaseAssembly, maturation, and trafficking of the gamma-secretase complex in Alzheimer's disease.Alzheimer's disease: the lipid connection.C-terminal PAL motif of presenilin and presenilin homologues required for normal active site conformation.Identification of gamma-secretase inhibitor potency determinants on presenilin.Contribution of presenilin transmembrane domains 6 and 7 to a water-containing cavity in the gamma-secretase complex.
P2860
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P2860
Evidence that the COOH terminus of human presenilin 1 is located in extracytoplasmic space.
description
2005 nî lūn-bûn
@nan
2005 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
name
Evidence that the COOH terminu ...... ted in extracytoplasmic space.
@ast
Evidence that the COOH terminu ...... ted in extracytoplasmic space.
@en
Evidence that the COOH terminu ...... ted in extracytoplasmic space.
@nl
type
label
Evidence that the COOH terminu ...... ted in extracytoplasmic space.
@ast
Evidence that the COOH terminu ...... ted in extracytoplasmic space.
@en
Evidence that the COOH terminu ...... ted in extracytoplasmic space.
@nl
prefLabel
Evidence that the COOH terminu ...... ted in extracytoplasmic space.
@ast
Evidence that the COOH terminu ...... ted in extracytoplasmic space.
@en
Evidence that the COOH terminu ...... ted in extracytoplasmic space.
@nl
P2860
P1476
Evidence that the COOH terminu ...... ted in extracytoplasmic space.
@en
P2093
R James Turner
Young S Oh
P2860
P304
P356
10.1152/AJPCELL.00636.2004
P577
2005-04-20T00:00:00Z