A human iPSC model of Ligase IV deficiency reveals an important role for NHEJ-mediated-DSB repair in the survival and genomic stability of induced pluripotent stem cells and emerging haematopoietic progenitors.
about
DNA repair and aging: the impact of the p53 familyBalancing self-renewal against genome preservation in stem cells: How do they manage to have the cake and eat it too?Homeodomain-Interacting Protein Kinase-2: A Critical Regulator of the DNA Damage Response and the EpigenomeDNA ligase IV syndrome; a reviewHigh-Fidelity Reprogrammed Human IPSCs Have a High Efficacy of DNA Repair and Resemble hESCs in Their MYC Transcriptional SignatureDifferential role of nonhomologous end joining factors in the generation, DNA damage response, and myeloid differentiation of human induced pluripotent stem cells.High-risk human papillomavirus E6 protein promotes reprogramming of Fanconi anemia patient cells through repression of p53 but does not allow for sustained growth of induced pluripotent stem cells.Brief report: a human induced pluripotent stem cell model of cernunnos deficiency reveals an important role for XLF in the survival of the primitive hematopoietic progenitors.Stem cells: the pursuit of genomic stability.BRCA1 silencing is associated with failure of DNA repairing in retinal neurocytesCtIP-Specific Roles during Cell Reprogramming Have Long-Term Consequences in the Survival and Fitness of Induced Pluripotent Stem CellsMechanisms underlying the formation of induced pluripotent stem cells.LIG4 mediates Wnt signalling-induced radioresistance.Integrating Gene Correction in the Reprogramming and Transdifferentiation Processes: A One-Step Strategy to Overcome Stem Cell-Based Gene Therapy Limitations.Generation of Gross Chromosomal Rearrangements by a Single Engineered DNA Double Strand Break.Nijmegen Breakage Syndrome fibroblasts and iPSCs: cellular models for uncovering disease-associated signaling pathways and establishing a screening platform for anti-oxidantsInduced Pluripotent Stem Cells: Advances in the Quest for Genetic Stability during Reprogramming Process.Reprogramming and genome integrity: role of non-homologous end joining.Generation of iPSCs from genetically corrected Brca2 hypomorphic cells: implications in cell reprogramming and stem cell therapy.CtIP fusion to Cas9 enhances transgene integration by homology-dependent repair.
P2860
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P2860
A human iPSC model of Ligase IV deficiency reveals an important role for NHEJ-mediated-DSB repair in the survival and genomic stability of induced pluripotent stem cells and emerging haematopoietic progenitors.
description
2013 nî lūn-bûn
@nan
2013 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2013 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
name
A human iPSC model of Ligase I ...... ng haematopoietic progenitors.
@ast
A human iPSC model of Ligase I ...... ng haematopoietic progenitors.
@en
A human iPSC model of Ligase I ...... ng haematopoietic progenitors.
@nl
type
label
A human iPSC model of Ligase I ...... ng haematopoietic progenitors.
@ast
A human iPSC model of Ligase I ...... ng haematopoietic progenitors.
@en
A human iPSC model of Ligase I ...... ng haematopoietic progenitors.
@nl
prefLabel
A human iPSC model of Ligase I ...... ng haematopoietic progenitors.
@ast
A human iPSC model of Ligase I ...... ng haematopoietic progenitors.
@en
A human iPSC model of Ligase I ...... ng haematopoietic progenitors.
@nl
P2093
P2860
P50
P356
P1476
A human iPSC model of Ligase I ...... ing haematopoietic progenitors
@en
P2093
C Singhapol
J Y Al-Aama
M Stojkovic
S Przyborski
P2860
P2888
P304
P356
10.1038/CDD.2013.44
P577
2013-05-31T00:00:00Z