Crystal structure of ovalbumin as a model for the reactive centre of serpins.
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Probing serpin reactive-loop conformations by proteolytic cleavageThe ovalbumin serpins revisited: perspective from the chicken genome of clade B serpin evolution in vertebratesHSP47: a tissue-specific, transformation-sensitive, collagen-binding heat shock protein of chicken embryo fibroblastsThromboembolic disease due to thermolabile conformational changes of antithrombin Rouen-VI (187 Asn-->Asp)Importance of the release of strand 1C to the polymerization mechanism of inhibitory serpinsPepsin-inhibitory activity of the uterine serpinsAnalysis of vertebrate genomes suggests a new model for clade B serpin evolution.Topography of a 2.0 Å structure of α1-antitrypsin reveals targets for rational drug design to prevent conformational diseaseCrystal structure of S-ovalbumin as a non-loop-inserted thermostabilized serpin formMechanisms contributing to the conformational and functional flexibility of plasminogen activator inhibitor-1The intact and cleaved human antithrombin III complex as a model for serpin-proteinase interactionsCrystal structure of an uncleaved alpha 1-antitrypsin reveals the conformation of its inhibitory reactive loopInhibitory conformation of the reactive loop of alpha 1-antitrypsinPlasminogen-activator inhibitor type 2 (PAI-2) is a spontaneously polymerising SERPIN. Biochemical characterisation of the recombinant intracellular and extracellular formsEvolution of murine alpha 1-proteinase inhibitors: gene amplification and reactive center divergenceIgM-linked SerpinB3 and SerpinB4 in sera of patients with chronic liver diseaseA structure-derived snap-trap mechanism of a multispecific serpin from the dysbiotic human oral microbiome.The murine Spi-2 proteinase inhibitor locus: a multigene family with a hypervariable reactive site domain.A redox-sensitive loop regulates plasminogen activator inhibitor type 2 (PAI-2) polymerizationEpitope mapping for four monoclonal antibodies against human plasminogen activator inhibitor type-1: implications for antibody-mediated PAI-1-neutralization and vitronectin-binding.Partitioning of serpin-proteinase reactions between stable inhibition and substrate cleavage is regulated by the rate of serpin reactive center loop insertion into beta-sheet A.Identification of centerin: a novel human germinal center B cell-restricted serpin.What do dysfunctional serpins tell us about molecular mobility and disease?C1 inhibitor hinge region mutations produce dysfunction by different mechanisms.Squamous cell carcinoma antigen is a potent inhibitor of cysteine proteinase cathepsin L.Porous protein-based scaffolds prepared through freezing as potential scaffolds for tissue engineering.SERPINB3 (serpin peptidase inhibitor, clade B (ovalbumin), member 3).Alanine and proline content modulate global sensitivity to discrete perturbations in disordered proteins.SERPINB11 is a new noninhibitory intracellular serpin. Common single nucleotide polymorphisms in the scaffold impair conformational change.Blocking formation of large protein aggregates by small peptides.Structural insights into the unique inhibitory mechanism of the silkworm protease inhibitor serpin18.Serpin alpha 1proteinase inhibitor probed by intrinsic tryptophan fluorescence spectroscopyStructural investigation of the alpha-1-antichymotrypsin: prostate-specific antigen complex by comparative model buildingThe human serpin proteinase inhibitor-9 self-associates at physiological temperatures.What we owe to alpha(1)-antitrypsin and to Carl-Bertil Laurell.Molecular evolution of plasminogen activator inhibitor-1 functional stabilityIdentification of tissue-type plasminogen activator-specific plasminogen activator inhibitor-1 mutants. Evidence that second sites of interaction contribute to target specificity.Antibody-probed conformational transitions in the protease domain of human factor IX upon calcium binding and zymogen activation: putative high-affinity Ca(2+)-binding site in the protease domainNeuroserpin, an axonally secreted serine protease inhibitor.Discontinuous native protein gel electrophoresis: pros and cons.
P2860
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P2860
Crystal structure of ovalbumin as a model for the reactive centre of serpins.
description
1990 nî lūn-bûn
@nan
1990 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
1990 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
1990年の論文
@ja
1990年論文
@yue
1990年論文
@zh-hant
1990年論文
@zh-hk
1990年論文
@zh-mo
1990年論文
@zh-tw
1990年论文
@wuu
name
Crystal structure of ovalbumin as a model for the reactive centre of serpins.
@ast
Crystal structure of ovalbumin as a model for the reactive centre of serpins.
@en
Crystal structure of ovalbumin as a model for the reactive centre of serpins.
@nl
type
label
Crystal structure of ovalbumin as a model for the reactive centre of serpins.
@ast
Crystal structure of ovalbumin as a model for the reactive centre of serpins.
@en
Crystal structure of ovalbumin as a model for the reactive centre of serpins.
@nl
prefLabel
Crystal structure of ovalbumin as a model for the reactive centre of serpins.
@ast
Crystal structure of ovalbumin as a model for the reactive centre of serpins.
@en
Crystal structure of ovalbumin as a model for the reactive centre of serpins.
@nl
P2093
P356
P1433
P1476
Crystal structure of ovalbumin as a model for the reactive centre of serpins.
@en
P2093
P2888
P304
P356
10.1038/347099A0
P407
P577
1990-09-01T00:00:00Z
P6179
1036372102