G4 DNA unwinding by BLM and Sgs1p: substrate specificity and substrate-specific inhibition. - Wikidata - wikimedia - TriplyDB

G4 DNA unwinding by BLM and Sgs1p: substrate specificity and substrate-specific inhibition.

G4 DNA unwinding by BLM and Sgs1p: substrate specificity and substrate-specific inhibition.

http://www.wikidata.org/entity/Q34367524

about

The Werner syndrome protein is distinguished from the Bloom syndrome protein by its capacity to tightly bind diverse DNA structures G4 resolvase 1 tightly binds and unwinds unimolecular G4-DNA Human POT1 disrupts telomeric G-quadruplexes allowing telomerase extension in vitro.The RecQ DNA helicases in DNA repair The Bloom's syndrome helicase (BLM) interacts physically and functionally with p12, the smallest subunit of human DNA polymerase delta In vivo veritas: using yeast to probe the biological functions of G-quadruplexes Human premature aging, DNA repair and RecQ helicases Vertebrate telomere repeat DNAs favor external loop propeller quadruplex structures in the presence of high concentrations of potassium.Formation and properties of hairpin and tetraplex structures of guanine-rich regulatory sequences of muscle-specific genes The Bloom's syndrome helicase promotes the annealing of complementary single-stranded DNA Evidence that the S.cerevisiae Sgs1 protein facilitates recombinational repair of telomeres during senescence.G-quadruplexes and helicases Nucleolin inhibits G4 oligonucleotide unwinding by Werner helicase RecA-Binding pilE G4 Sequence Essential for Pilin Antigenic Variation Forms Monomeric and 5′ End-Stacked Dimeric Parallel G-Quadruplexes Evidence that a RecQ helicase slows senescence by resolving recombining telomeres Telomere shortening exposes functions for the mouse Werner and Bloom syndrome genes Human replication protein A unfolds telomeric G-quadruplexes Unwinding protein complexes in ALTernative telomere maintenance.Processing of G4 DNA by Dna2 helicase/nuclease and replication protein A (RPA) provides insights into the mechanism of Dna2/RPA substrate recognition.Distinct activities of exonuclease 1 and flap endonuclease 1 at telomeric g4 DNA PARP3 is a promoter of chromosomal rearrangements and limits G4 DNA.G-quadruplex DNA sequences are evolutionarily conserved and associated with distinct genomic features in Saccharomyces cerevisiae Formation of complex and unstable chromosomal translocations in yeast Altered gene expression in the Werner and Bloom syndromes is associated with sequences having G-quadruplex forming potential.The full-length Saccharomyces cerevisiae Sgs1 protein is a vigorous DNA helicase that preferentially unwinds holliday junctions.G-quadruplex conformation and dynamics are determined by loop length and sequence.Conserved helicase domain of human RecQ4 is required for strand annealing-independent DNA unwinding.Stabilization of a G-Quadruplex from Unfolding by Replication Protein A Using Potassium and the Porphyrin TMPyP4 Genetic instability triggered by G-quadruplex interacting Phen-DC compounds in Saccharomyces cerevisiae.G-quadruplex nucleic acids and human disease Phosphorylation of BLM, dissociation from topoisomerase IIIalpha, and colocalization with gamma-H2AX after topoisomerase I-induced replication damage.Mycobacterium tuberculosis DinG is a structure-specific helicase that unwinds G4 DNA: implications for targeting G4 DNA as a novel therapeutic approach.Junction of RecQ helicase biochemistry and human disease.RecQ-core of BLM unfolds telomeric G-quadruplex in the absence of ATP G-quadruplex recognition activities of E. Coli MutS.DNA and RNA quadruplex-binding proteins.TRF1 negotiates TTAGGG repeat-associated replication problems by recruiting the BLM helicase and the TPP1/POT1 repressor of ATR signaling.Mechanistic insight into the interaction of BLM helicase with intra-strand G-quadruplex structures Mobile D-loops are a preferred substrate for the Bloom's syndrome helicase.hnRNP A1 associates with telomere ends and stimulates telomerase activity

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G4 DNA unwinding by BLM and Sgs1p: substrate specificity and substrate-specific inhibition.

http://www.wikidata.org/entity/Q34367524

description

2002 nî lūn-bûn

@nan

2002 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած

@hyw

2002 թվականի սեպտեմբերին հրատարակված գիտական հոդված

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2002年の論文

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2002年論文

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2002年論文

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2002年論文

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2002年論文

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2002年論文

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2002年论文

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name

G4 DNA unwinding by BLM and Sg ...... substrate-specific inhibition.

@ast

G4 DNA unwinding by BLM and Sg ...... substrate-specific inhibition.

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G4 DNA unwinding by BLM and Sg ...... substrate-specific inhibition.

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type

label

G4 DNA unwinding by BLM and Sg ...... substrate-specific inhibition.

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G4 DNA unwinding by BLM and Sg ...... substrate-specific inhibition.

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G4 DNA unwinding by BLM and Sg ...... substrate-specific inhibition.

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prefLabel

G4 DNA unwinding by BLM and Sg ...... substrate-specific inhibition.

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G4 DNA unwinding by BLM and Sg ...... substrate-specific inhibition.

@en

G4 DNA unwinding by BLM and Sg ...... substrate-specific inhibition.

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Nucleic Acids Research

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G4 DNA unwinding by BLM and Sg ...... substrate-specific inhibition.

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P2093

Damian C Lee

http://www.w3.org/2001/XMLSchema#string

Michael D Huber

http://www.w3.org/2001/XMLSchema#string

Nancy Maizels

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P2860

Mutations in RECQL4 cause a subset of cases of Rothmund-Thomson syndrome

Association of the Bloom syndrome protein with topoisomerase IIIalpha in somatic and meiotic cells

Replication protein A physically interacts with the Bloom's syndrome protein and stimulates its helicase activity

Regulation and localization of the Bloom syndrome protein in response to DNA damage

The Bloom's and Werner's syndrome proteins are DNA structure-specific helicases

Colocalization, physical, and functional interaction between Werner and Bloom syndrome proteins

The Bloom's syndrome gene product is a 3'-5' DNA helicase

The Bloom's syndrome gene product is homologous to RecQ helicases

BASC, a super complex of BRCA1-associated proteins involved in the recognition and repair of aberrant DNA structures

The Bloom's syndrome gene product promotes branch migration of holliday junctions

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3954-3961

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scholarly article

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10.1093/NAR/GKF530

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18

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30

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279723065

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12235379

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137114

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