The Bloom's syndrome gene product is a 3'-5' DNA helicase
about
The Werner syndrome protein is distinguished from the Bloom syndrome protein by its capacity to tightly bind diverse DNA structuresTIP49b, a new RuvB-like DNA helicase, is included in a complex together with another RuvB-like DNA helicase, TIP49aReplication protein A physically interacts with the Bloom's syndrome protein and stimulates its helicase activityPotent inhibition of werner and bloom helicases by DNA minor groove binding drugsRegulation and localization of the Bloom syndrome protein in response to DNA damageThe Bloom's and Werner's syndrome proteins are DNA structure-specific helicasesColocalization, physical, and functional interaction between Werner and Bloom syndrome proteinsStructural and functional analyses of disease-causing missense mutations in Bloom syndrome proteinBLAP75, an essential component of Bloom's syndrome protein complexes that maintain genome integrityStimulation of flap endonuclease-1 by the Bloom's syndrome proteinHuman topoisomerase IIIalpha is a single-stranded DNA decatenase that is stimulated by BLM and RMI1Scaffolding protein SPIDR/KIAA0146 connects the Bloom syndrome helicase with homologous recombination repairCharacterization of the enzymatic activity of hChlR1, a novel human DNA helicaseThe Bloom's syndrome helicase stimulates the activity of human topoisomerase IIIalphaBLAP75/RMI1 promotes the BLM-dependent dissolution of homologous recombination intermediatesRequirement for three novel protein complexes in the absence of the Sgs1 DNA helicase in Saccharomyces cerevisiaeDirect association of Bloom's syndrome gene product with the human mismatch repair protein MLH1Cleavage of the Bloom's syndrome gene product during apoptosis by caspase-3 results in an impaired interaction with topoisomerase IIIalphaPhysical and functional interaction between the Bloom's syndrome gene product and the largest subunit of chromatin assembly factor 1Analysis of the unwinding activity of the dimeric RECQ1 helicase in the presence of human replication protein AThe BRCA1-associated protein BACH1 is a DNA helicase targeted by clinically relevant inactivating mutationsHuman pyruvate kinase M2: a multifunctional proteinThe Bloom's syndrome helicase (BLM) interacts physically and functionally with p12, the smallest subunit of human DNA polymerase deltaA multiprotein nuclear complex connects Fanconi anemia and Bloom syndromeDomain mapping of Escherichia coli RecQ defines the roles of conserved N- and C-terminal regions in the RecQ familyThe Bloom's syndrome gene product promotes branch migration of holliday junctionsHuman RECQ5beta helicase promotes strand exchange on synthetic DNA structures resembling a stalled replication forkSomatic frameshift mutations in the Bloom syndrome BLM gene are frequent in sporadic gastric carcinomas with microsatellite mutator phenotypeStructural and functional characterizations reveal the importance of a zinc binding domain in Bloom's syndrome helicaseThe Bloom's syndrome helicase promotes the annealing of complementary single-stranded DNACompetition between the DNA unwinding and strand pairing activities of the Werner and Bloom syndrome proteinsStructure and function of the regulatory HRDC domain from human Bloom syndrome proteinStructure of human Bloom's syndrome helicase in complex with ADP and duplex DNAThe Saccharomyces cerevisiae Sgs1 helicase efficiently unwinds G-G paired DNAs.Saccharomyces cerevisiae Mer3 is a DNA helicase involved in meiotic crossing overThe MER3 DNA helicase catalyzes the unwinding of holliday junctions.Role of SGS1 and SLX4 in maintaining rDNA structure in Saccharomyces cerevisiae.Binding and activation of DNA topoisomerase III by the Rmi1 subunit.Cell cycle regulation of the endogenous wild type Bloom's syndrome DNA helicaseThe Bloom's syndrome gene product interacts with topoisomerase III
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The Bloom's syndrome gene product is a 3'-5' DNA helicase
description
1997 nî lūn-bûn
@nan
1997 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
1997 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
1997年の論文
@ja
1997年論文
@yue
1997年論文
@zh-hant
1997年論文
@zh-hk
1997年論文
@zh-mo
1997年論文
@zh-tw
1997年论文
@wuu
name
The Bloom's syndrome gene product is a 3'-5' DNA helicase
@ast
The Bloom's syndrome gene product is a 3'-5' DNA helicase
@en
The Bloom's syndrome gene product is a 3'-5' DNA helicase
@en-gb
The Bloom's syndrome gene product is a 3'-5' DNA helicase
@nl
type
label
The Bloom's syndrome gene product is a 3'-5' DNA helicase
@ast
The Bloom's syndrome gene product is a 3'-5' DNA helicase
@en
The Bloom's syndrome gene product is a 3'-5' DNA helicase
@en-gb
The Bloom's syndrome gene product is a 3'-5' DNA helicase
@nl
prefLabel
The Bloom's syndrome gene product is a 3'-5' DNA helicase
@ast
The Bloom's syndrome gene product is a 3'-5' DNA helicase
@en
The Bloom's syndrome gene product is a 3'-5' DNA helicase
@en-gb
The Bloom's syndrome gene product is a 3'-5' DNA helicase
@nl
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P1476
The Bloom's syndrome gene product is a 3'-5' DNA helicase
@en
P2093
I D Hickson
R K Chakraverty
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P304
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10.1074/JBC.272.49.30611
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1997-12-05T00:00:00Z