The t(3;5)(q25.1;q34) of myelodysplastic syndrome and acute myeloid leukemia produces a novel fusion gene, NPM-MLF1.
about
Myeloid leukemia factor 1 regulates p53 by suppressing COP1 via COP9 signalosome subunit 3Role of the nucleophosmin (NPM) portion of the non-Hodgkin's lymphoma-associated NPM-anaplastic lymphoma kinase fusion protein in oncogenesisLoading and unloading: orchestrating centrosome duplication and spindle assembly by Ran/Crm1Shuttling imbalance of MLF1 results in p53 instability and increases susceptibility to oncogenic transformationNucleophosmin: from structure and function to disease developmentMolecules that target nucleophosmin for cancer treatment: an updateEngineering mouse models with myelodysplastic syndrome human candidate genes; how relevant are they?Myeloma overexpressed 2 (Myeov2) regulates L11 subnuclear localization through Nedd8 modificationCul4A targets p27 for degradation and regulates proliferation, cell cycle exit, and differentiation during erythropoiesisGLTSCR2 is an upstream negative regulator of nucleophosmin in cervical cancer.Nucleophosmin suppresses oncogene-induced apoptosis and senescence and enhances oncogenic cooperation in cells with genomic instability.Clinical relevance of mutant NPM1 and CEBPA in patients with acute myeloid leukaemia - preliminary reportNucleolar adaptation in human cancerIsolation and characterization of the human nucleophosmin/B23 (NPM) gene: identification of the YY1 binding site at the 5' enhancer regionNucleophosmin (NPM1) mutations in adult and childhood acute myeloid leukaemia: towards definition of a new leukaemia entity.Knockdown of NPM1 by RNA interference inhibits cells proliferation and induces apoptosis in leukemic cell line.Clinical relevance of mutations and gene-expression changes in adult acute myeloid leukemia with normal cytogenetics: are we ready for a prognostically prioritized molecular classification?cDNA cloning, expression pattern, and chromosomal localization of Mlf1, murine homologue of a gene involved in myelodysplasia and acute myeloid leukemiaATIC-ALK: A novel variant ALK gene fusion in anaplastic large cell lymphoma resulting from the recurrent cryptic chromosomal inversion, inv(2)(p23q35).Sumoylation of nucleophosmin/B23 regulates its subcellular localization, mediating cell proliferation and survival.Myeloid leukemia factor is a conserved regulator of RUNX transcription factor activity involved in hematopoiesis.Common variants upstream of MLF1 at 3q25 and within CPZ at 4p16 associated with neuroblastoma.Npm1 is a haploinsufficient suppressor of myeloid and lymphoid malignancies in the mouse.The novel tumour suppressor Madm regulates stem cell competition in the Drosophila testisRapid method for detection of mutations in the nucleophosmin gene in acute myeloid leukemia.Acute myeloid leukemia with translocation t(3;5): new molecular insights.The natural product avrainvillamide binds to the oncoprotein nucleophosmin.AML1/RUNX1 works as a negative regulator of c-Mpl in hematopoietic stem cells.A single center analysis of nucleophosmin in acute myeloid leukemia: value of combining immunohistochemistry with molecular mutation analysisCandidate Genes for Inherited Autism Susceptibility in the Lebanese Population.Mutation of cysteine 21 inhibits nucleophosmin/B23 oligomerization and chaperone activityControl of RUNX-induced repression of Notch signaling by MLF and its partner DnaJ-1 during Drosophila hematopoiesis.Relevance of Fusion Genes in Pediatric Cancers: Toward Precision Medicine.Drosophila myeloid leukemia factor acts with DREF to activate the JNK signaling pathway.Myeloid leukemia factor: a return ticket from human leukemia to fly hematopoiesis.A genome-wide RNA interference screen identifies a differential role of the mediator CDK8 module subunits for GATA/ RUNX-activated transcription in Drosophila.Nucleophosmin (B23) targets ARF to nucleoli and inhibits its function.The CRM1 nuclear export protein in normal development and disease.Denaturing high-performance liquid chromatography: a valid approach for identifying NPM1 mutations in acute myeloid leukemia.Extrinsic apoptosis is impeded by direct binding of the APL fusion protein NPM-RAR to TRADD.
P2860
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P2860
The t(3;5)(q25.1;q34) of myelodysplastic syndrome and acute myeloid leukemia produces a novel fusion gene, NPM-MLF1.
description
1996 nî lūn-bûn
@nan
1996 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
1996 թվականի հունվարին հրատարակված գիտական հոդված
@hy
1996年の論文
@ja
1996年論文
@yue
1996年論文
@zh-hant
1996年論文
@zh-hk
1996年論文
@zh-mo
1996年論文
@zh-tw
1996年论文
@wuu
name
The t(3;5)(q25.1;q34) of myelo ...... a novel fusion gene, NPM-MLF1.
@ast
The t(3;5)(q25.1;q34) of myelo ...... a novel fusion gene, NPM-MLF1.
@en
The t(3;5)(q25.1;q34) of myelo ...... a novel fusion gene, NPM-MLF1.
@nl
type
label
The t(3;5)(q25.1;q34) of myelo ...... a novel fusion gene, NPM-MLF1.
@ast
The t(3;5)(q25.1;q34) of myelo ...... a novel fusion gene, NPM-MLF1.
@en
The t(3;5)(q25.1;q34) of myelo ...... a novel fusion gene, NPM-MLF1.
@nl
prefLabel
The t(3;5)(q25.1;q34) of myelo ...... a novel fusion gene, NPM-MLF1.
@ast
The t(3;5)(q25.1;q34) of myelo ...... a novel fusion gene, NPM-MLF1.
@en
The t(3;5)(q25.1;q34) of myelo ...... a novel fusion gene, NPM-MLF1.
@nl
P2093
P1433
P1476
The t(3;5)(q25.1;q34) of myelo ...... a novel fusion gene, NPM-MLF1
@en
P2093
Carroll AJ
Kirstein MN
Raimondi SC
Valentine MB
Yoneda-Kato N
P304
P407
P577
1996-01-01T00:00:00Z