DNA damage signaling in hematopoietic cells: a role for Mre11 complex repair of topoisomerase lesions

DNA damage signaling in hematopoietic cells: a role for Mre11 complex repair of topoisomerase lesions

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http://www.wikidata.org/entity/Q34373684
Rad50 is dispensable for the maintenance and viability of postmitotic tissuesMutation of NIMA-related kinase 1 (NEK1) leads to chromosome instabilityInterdependence of the rad50 hook and globular domain functionsMRE11 facilitates the removal of human topoisomerase II complexes from genomic DNA.Myelodysplastic syndrome: an inability to appropriately respond to damaged DNA?Loss of aryl hydrocarbon receptor promotes gene changes associated with premature hematopoietic stem cell exhaustion and development of a myeloproliferative disorder in aging mice.The MRE11 complex: starting from the ends.The p53 tumor suppressor protein is a critical regulator of hematopoietic stem cell behavior.The Rad50 hook domain regulates DNA damage signaling and tumorigenesis.Making the best of the loose ends: Mre11/Rad50 complexes and Sae2 promote DNA double-strand break resection.Generation of a novel, multi-stage, progressive, and transplantable model of plasma cell neoplasms.Functional interplay of the Mre11 nuclease and Ku in the response to replication-associated DNA damage.The mef/elf4 transcription factor fine tunes the DNA damage response.Topoisomerase I (Top1): a major target of FL118 for its antitumor efficacy or mainly involved in its side effects of hematopoietic toxicity?
P2860

DNA damage signaling in hematopoietic cells: a role for Mre11 complex repair of topoisomerase lesions

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http://www.wikidata.org/entity/Q34373684
description
2008 nî lūn-bûn
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2008 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
DNA damage signaling in hemato ...... epair of topoisomerase lesions
@ast
DNA damage signaling in hemato ...... epair of topoisomerase lesions
@en
DNA damage signaling in hemato ...... epair of topoisomerase lesions
@nl
type
label
DNA damage signaling in hemato ...... epair of topoisomerase lesions
@ast
DNA damage signaling in hemato ...... epair of topoisomerase lesions
@en
DNA damage signaling in hemato ...... epair of topoisomerase lesions
@nl
prefLabel
DNA damage signaling in hemato ...... epair of topoisomerase lesions
@ast
DNA damage signaling in hemato ...... epair of topoisomerase lesions
@en
DNA damage signaling in hemato ...... epair of topoisomerase lesions
@nl
P1433
P1476
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P2860
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P5875
P698
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DNA damage signaling in hemato ...... epair of topoisomerase lesions
@en
P2093
P2860
P304
P31
P356
10.1158/0008-5472.CAN-07-2355
P407
P433
P478
P577
P5875
P698
P921
P932