Genes and cellular requirements for autoimmune diabetes susceptibility in nonobese diabetic mice.
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Identification of the beta cell antigen targeted by a prevalent population of pathogenic CD8+ T cells in autoimmune diabetes.Construction and analysis of tag single nucleotide polymorphism maps for six human-mouse orthologous candidate genes in type 1 diabetesFunctional evidence for the mediation of diabetogenic T cell responses by HLA-A2.1 MHC class I molecules through transgenic expression in NOD mice.Idd9.1 locus controls the suppressive activity of FoxP3+CD4+CD25+ regulatory T-cellsMolecular pathway alterations in CD4 T-cells of nonobese diabetic (NOD) mice in the preinsulitis phase of autoimmune diabetes.Genes within the Idd5 and Idd9/11 diabetes susceptibility loci affect the pathogenic activity of B cells in nonobese diabetic mice.Change you can B(cell)eive in: recent progress confirms a critical role for B cells in type 1 diabetes.The islet-specific glucose-6-phosphatase-related protein, implicated in diabetes, is a glycoprotein embedded in the endoplasmic reticulum membrane.A recombination hotspot leads to sequence variability within a novel gene (AK005651) and contributes to type 1 diabetes susceptibilityMolecular phenotyping of immune cells from young NOD mice reveals abnormal metabolic pathways in the early induction phase of autoimmune diabetesInterleukin-1β produced in response to islet autoantigen presentation differentiates T-helper 17 cells at the expense of regulatory T-cells: Implications for the timing of tolerizing immunotherapy.The nonconventional MHC class II molecule DM governs diabetes susceptibility in NOD micePrevention of "Humanized" diabetogenic CD8 T-cell responses in HLA-transgenic NOD mice by a multipeptide coupled-cell approachHLA-A2-matched peripheral blood mononuclear cells from type 1 diabetic patients, but not nondiabetic donors, transfer insulitis to NOD-scid/γc(null)/HLA-A2 transgenic mice concurrent with the expansion of islet-specific CD8+ T cells.Prevention of autoimmune diabetes by DNA vaccination.Postnatal Hematopoiesis and Gut Microbiota in NOD Mice Deviate from C57BL/6 MiceLoss of T cell progenitor checkpoint control underlies leukemia initiation in Rag1-deficient nonobese diabetic mice.Idd9/11 genetic locus regulates diabetogenic activity of CD4 T-cells in nonobese diabetic (NOD) mice.B cell selection defects underlie the development of diabetogenic APCs in nonobese diabetic miceγδ T cells are essential effectors of type 1 diabetes in the nonobese diabetic mouse model.Tissue distribution and clonal diversity of the T and B cell repertoire in type 1 diabetesMouse models for the study of autoimmune type 1 diabetes: a NOD to similarities and differences to human disease.Adenovirus early region 3 transgenes expressed in beta cells prevent autoimmune diabetes in nonobese diabetic mice: effects of deleting the adenovirus death protein 11.6K.At the crossroad of T cells, adipose tissue, and diabetes.The case for an autoimmune aetiology of type 1 diabetes.DNA vaccination with an insulin construct and a chimeric protein binding to both CTLA4 and CD40 ameliorates type 1 diabetes in NOD mice.The A-chain of insulin is a hot-spot for CD4+ T cell epitopes in human type 1 diabetes.Lrmp and Bcat1 are candidates for the type I diabetes susceptibility locus Idd6.Recent insights into CD4+T-cell specificity and function in Type 1 diabetes
P2860
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P2860
Genes and cellular requirements for autoimmune diabetes susceptibility in nonobese diabetic mice.
description
2001 nî lūn-bûn
@nan
2001 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
Genes and cellular requirement ...... ity in nonobese diabetic mice.
@ast
Genes and cellular requirement ...... ity in nonobese diabetic mice.
@en
Genes and cellular requirement ...... ity in nonobese diabetic mice.
@nl
type
label
Genes and cellular requirement ...... ity in nonobese diabetic mice.
@ast
Genes and cellular requirement ...... ity in nonobese diabetic mice.
@en
Genes and cellular requirement ...... ity in nonobese diabetic mice.
@nl
prefLabel
Genes and cellular requirement ...... ity in nonobese diabetic mice.
@ast
Genes and cellular requirement ...... ity in nonobese diabetic mice.
@en
Genes and cellular requirement ...... ity in nonobese diabetic mice.
@nl
P356
P1476
Genes and cellular requirement ...... ity in nonobese diabetic mice.
@en
P2093
P356
10.1159/000060527
P577
2001-01-01T00:00:00Z