Idd9/11 genetic locus regulates diabetogenic activity of CD4 T-cells in nonobese diabetic (NOD) mice.
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Idd9.1 locus controls the suppressive activity of FoxP3+CD4+CD25+ regulatory T-cellsMolecular pathway alterations in CD4 T-cells of nonobese diabetic (NOD) mice in the preinsulitis phase of autoimmune diabetes.Idd9.2 and Idd9.3 protective alleles function in CD4+ T-cells and nonlymphoid cells to prevent expansion of pathogenic islet-specific CD8+ T-cells.Testing the role of P2X7 receptors in the development of type 1 diabetes in nonobese diabetic micePathological features of new animal models for primary biliary cirrhosis.Genome-wide transcriptional analyses of islet-specific CD4+ T cells identify Idd9 genes controlling diabetogenic T cell functionLoss of intra-islet CD20 expression may complicate efficacy of B-cell-directed type 1 diabetes therapiesSubcongenic analyses reveal complex interactions between distal chromosome 4 genes controlling diabetogenic B cells and CD4 T cells in nonobese diabetic mice.Fine mapping of type 1 diabetes regions Idd9.1 and Idd9.2 reveals genetic complexity.Gene targeting in NOD mouse embryos using zinc-finger nucleases.Mouse models for the study of autoimmune type 1 diabetes: a NOD to similarities and differences to human disease.Congenic mapping identifies a novel Idd9 subregion regulating type 1 diabetes in NOD mice.The Role of NOD Mice in Type 1 Diabetes Research: Lessons from the Past and Recommendations for the Future.
P2860
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P2860
Idd9/11 genetic locus regulates diabetogenic activity of CD4 T-cells in nonobese diabetic (NOD) mice.
description
2008 nî lūn-bûn
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2008年の論文
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2008年論文
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2008年論文
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2008年論文
@zh-hk
2008年論文
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2008年論文
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2008年论文
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2008年论文
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2008年论文
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name
Idd9/11 genetic locus regulate ...... nonobese diabetic (NOD) mice.
@en
type
label
Idd9/11 genetic locus regulate ...... nonobese diabetic (NOD) mice.
@en
prefLabel
Idd9/11 genetic locus regulate ...... nonobese diabetic (NOD) mice.
@en
P2093
P2860
P356
P1433
P1476
Idd9/11 genetic locus regulate ...... nonobese diabetic (NOD) mice.
@en
P2093
David V Serreze
Felix Scheuplein
Harold D Chapman
Melissa A Osborne
Shirng-Wern Tsaih
Yi-Guang Chen
P2860
P304
P356
10.2337/DB08-0767
P407
P577
2008-09-05T00:00:00Z