Organization of the biosynthetic gene cluster for rapamycin in Streptomyces hygroscopicus: analysis of the enzymatic domains in the modular polyketide synthase.
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Deciphering the genetic basis for polyketide variation among mycobacteria producing mycolactonesGiant plasmid-encoded polyketide synthases produce the macrolide toxin of Mycobacterium ulceransComparison of the 1.85 A structure of CYP154A1 from Streptomyces coelicolor A3(2) with the closely related CYP154C1 and CYPs from antibiotic biosynthetic pathwaysKetoreduction in mycolactone biosynthesis: insight into substrate specificity and stereocontrol from studies of discrete ketoreductase domains in vitroEfficient purification and kinetic characterization of a bimodular derivative of the erythromycin polyketide synthaseA protein interaction surface in nonribosomal peptide synthesis mapped by combinatorial mutagenesis and selection.Characterization of the tautomycin biosynthetic gene cluster from Streptomyces spiroverticillatus unveiling new insights into dialkylmaleic anhydride and polyketide biosynthesis.Biosynthesis of the Pseudomonas polyketide coronafacic acid requires monofunctional and multifunctional polyketide synthase proteins.Mutational biosynthesis of novel rapamycins by a strain of Streptomyces hygroscopicus NRRL 5491 disrupted in rapL, encoding a putative lysine cyclodeaminase.Natural products version 2.0: connecting genes to molecules.LAL regulators SCO0877 and SCO7173 as pleiotropic modulators of phosphate starvation response and actinorhodin biosynthesis in Streptomyces coelicolorInsights into an unusual nonribosomal peptide synthetase biosynthesis: identification and characterization of the GE81112 biosynthetic gene cluster.Identification and characterization of the niddamycin polyketide synthase genes from Streptomyces caelestis.FK506 biosynthesis is regulated by two positive regulatory elements in Streptomyces tsukubaensisMarine Actinobacteria from the Gulf of California: diversity, abundance and secondary metabolite biosynthetic potential.A PKS/NRPS/FAS hybrid gene cluster from Serratia plymuthica RVH1 encoding the biosynthesis of three broad spectrum, zeamine-related antibiotics.Biosynthetic gene cluster for the polyenoyltetramic acid alpha-lipomycin.Biosynthesis of the immunosuppressants FK506, FK520, and rapamycin involves a previously undescribed family of enzymes acting on chorismateEngineering polyketide synthases and nonribosomal peptide synthetases.Recent developments in the production of novel polyketides by combinatorial biosynthesis.The enzymology of combinatorial biosynthesis.Multifunctional polyketide synthase genes identified by genomic survey of the symbiotic dinoflagellate, Symbiodinium minutum.Combinatorial biosynthesis: lesson learned from natureIdentification of the Polyketide Biosynthetic Machinery for the Indolizidine Alkaloid Cyclizidine.Genes coding for hepatotoxic heptapeptides (microcystins) in the cyanobacterium Anabaena strain 90A gene cluster for macrolide antibiotic biosynthesis in Streptomyces venezuelae: architecture of metabolic diversity.Molecular regulation of antibiotic biosynthesis in streptomyces.Mycolactones: immunosuppressive and cytotoxic polyketides produced by aquatic mycobacteria.iso-Migrastatin, migrastatin, and dorrigocin production in Streptomyces platensis NRRL 18993 is governed by a single biosynthetic machinery featuring an acyltransferase-less type I polyketide synthase.Biosynthesis of rapamycin and its regulation: past achievements and recent progress.Molecular diversity sculpted by fungal PKS-NRPS hybrids.History, biology and chemistry of Mycobacterium ulcerans infections (Buruli ulcer disease).Neocarzinostatin naphthoate synthase: an unique iterative type I PKS from neocarzinostatin producer Streptomyces carzinostaticus.The structural biology of biosynthetic megaenzymes.Isolation and identification of rhizoxin analogs from Pseudomonas fluorescens Pf-5 by using a genomic mining strategyGenetic engineering of modular PKSs: from combinatorial biosynthesis to synthetic biology.An overview of rapamycin: from discovery to future perspectives.Promiscuity of a modular polyketide synthase towards natural and non-natural extender units.Characterization and analysis of the PikD regulatory factor in the pikromycin biosynthetic pathway of Streptomyces venezuelaeThe yersiniabactin biosynthetic gene cluster of Yersinia enterocolitica: organization and siderophore-dependent regulation.
P2860
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P2860
Organization of the biosynthetic gene cluster for rapamycin in Streptomyces hygroscopicus: analysis of the enzymatic domains in the modular polyketide synthase.
description
1996 nî lūn-bûn
@nan
1996 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
1996 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
1996年の論文
@ja
1996年論文
@yue
1996年論文
@zh-hant
1996年論文
@zh-hk
1996年論文
@zh-mo
1996年論文
@zh-tw
1996年论文
@wuu
name
Organization of the biosynthet ...... e modular polyketide synthase.
@ast
Organization of the biosynthet ...... e modular polyketide synthase.
@en
Organization of the biosynthet ...... e modular polyketide synthase.
@nl
type
label
Organization of the biosynthet ...... e modular polyketide synthase.
@ast
Organization of the biosynthet ...... e modular polyketide synthase.
@en
Organization of the biosynthet ...... e modular polyketide synthase.
@nl
prefLabel
Organization of the biosynthet ...... e modular polyketide synthase.
@ast
Organization of the biosynthet ...... e modular polyketide synthase.
@en
Organization of the biosynthet ...... e modular polyketide synthase.
@nl
P2093
P1433
P1476
Organization of the biosynthet ...... e modular polyketide synthase.
@en
P2093
Aparicio JF
Haydock SF
Leadlay PF
Schwecke T
Staunton J
P356
10.1016/0378-1119(95)00800-4
P407
P577
1996-02-01T00:00:00Z