Glycine transporters as novel therapeutic targets in schizophrenia, alcohol dependence and pain.
about
NMDA receptor modulators: an updated patent review (2013-2014)Recent progress in understanding subtype specific regulation of NMDA receptors by G Protein Coupled Receptors (GPCRs)SLC transporters as therapeutic targets: emerging opportunitiesThe lidocaine metabolite N-ethylglycine has antinociceptive effects in experimental inflammatory and neuropathic pain.Time and space profiling of NMDA receptor co-agonist functionsSchizophrenia.Molecular basis of the dominant negative effect of a glycine transporter 2 mutation associated with hyperekplexia.1-aminocyclopropanecarboxylic acid (ACPC) produces procognitive but not antipsychotic-like effects in rats.Novel GlyT1 inhibitor chemotypes by scaffold hopping. Part 1: development of a potent and CNS penetrant [3.1.0]-based lead.Neurometabolic abnormalities in schizophrenia and depression observed with magnetic resonance spectroscopy at 7 T.Further characterization of the GlyT-1 inhibitor Org25935: anti-alcohol, neurobehavioral, and gene expression effects.Early investigational drugs for hearing loss.Synthesis and Pharmacological Properties of Novel Esters Based on Monoterpenoids and Glycine.Glycine receptors control the generation of projection neurons in the developing cerebral cortexDeletion of forebrain glycine transporter 1 enhances conditioned freezing to a reliable, but not an ambiguous, cue for threat in a conditioned freezing paradigm.Identification of a 3rd Na+ Binding Site of the Glycine Transporter, GlyT2.The astrocytic transporter SLC7A10 (Asc-1) mediates glycinergic inhibition of spinal cord motor neurons.Inhibition of glycine transporter-1 in the dorsal vagal complex improves metabolic homeostasis in diabetes and obesity.Emerging drugs for schizophrenia: an update.Inhibition of miR-203 Reduces Spontaneous Recurrent Seizures in Mice.Regulation of heme biosynthesis and transport in metazoa.Glycine receptors and glycine transporters: targets for novel analgesics?Assessment of the Target Engagement and D-Serine Biomarker Profiles of the D-Amino Acid Oxidase Inhibitors Sodium Benzoate and PGM030756.Piperazine derivatives for therapeutic use: a patent review (2010-present).Pharmacogenetic Analysis of Functional Glutamate System Gene Variants and Clinical Response to Clozapine.Calcium dependent interaction of calmodulin with the GlyT1 C-terminus.Enhancing NMDA Receptor Function: Recent Progress on Allosteric Modulators.Loss of Glycine Transporter 1 Causes a Subtype of Glycine Encephalopathy with Arthrogryposis and Mildly Elevated Cerebrospinal Fluid GlycineA brain proteomic investigation of rapamycin effects in the Tsc1+/- mouse model.Extracellular glycine is necessary for optimal hemoglobinization of erythroid cells.Changes in urinary amino acids excretion in relationship with muscle activity markers over a professional cycling stage race: in search of fatigue markers.Dysregulated Glycine Signaling Contributes to Increased Impulsivity during Protracted Alcohol Abstinence.Copper-Catalyzed Alkylation of Nitroalkanes with α-Bromonitriles: Synthesis of β-Cyanonitroalkanes.The GlyR Extracellular β8-β9 Loop - A Functional Determinant of Agonist Potency.Glycine Transporter 1 Inhibitors and the Promise of a New Schizophrenia TherapyPreclinical Reproductive and Developmental Toxicity Profile of a Glycine Transporter Type 1 (Glyt1) Inhibitor.Glycine Transporters and Its Coupling with NMDA Receptors.Glycine Transporters in Glia Cells: Structural Studies.The Glycine Receptor-A Functionally Important Primary Brain Target of Ethanol.Human SHMT inhibitors reveal defective glycine import as a targetable metabolic vulnerability of diffuse large B-cell lymphoma.
P2860
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P2860
Glycine transporters as novel therapeutic targets in schizophrenia, alcohol dependence and pain.
description
2013 nî lūn-bûn
@nan
2013 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2013 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
name
Glycine transporters as novel ...... , alcohol dependence and pain.
@ast
Glycine transporters as novel ...... , alcohol dependence and pain.
@en
Glycine transporters as novel ...... , alcohol dependence and pain.
@nl
type
label
Glycine transporters as novel ...... , alcohol dependence and pain.
@ast
Glycine transporters as novel ...... , alcohol dependence and pain.
@en
Glycine transporters as novel ...... , alcohol dependence and pain.
@nl
prefLabel
Glycine transporters as novel ...... , alcohol dependence and pain.
@ast
Glycine transporters as novel ...... , alcohol dependence and pain.
@en
Glycine transporters as novel ...... , alcohol dependence and pain.
@nl
P2860
P356
P1476
Glycine transporters as novel ...... , alcohol dependence and pain.
@en
P2093
Benjamin K Yee
P2860
P2888
P304
P356
10.1038/NRD3893
P577
2013-11-01T00:00:00Z