Haplotype mapping of a major quantitative-trait locus for fetal hemoglobin production, on chromosome 6q23.
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Genome annotation of a 1.5 Mb region of human chromosome 6q23 encompassing a quantitative trait locus for fetal hemoglobin expression in adultsHaploinsufficiency for the erythroid transcription factor KLF1 causes hereditary persistence of fetal hemoglobinChronic hyper-hemolysis in sickle cell anemia: association of vascular complications and mortality with less frequent vasoocclusive painTwo candidate genes for low platelet count identified in an Asian Indian kindred by genome-wide linkage analysis: glycoprotein IX and thrombopoietin.Sickle Cell Disease in the Post Genomic Era: A Monogenic Disease with a Polygenic Phenotype.Regulation of the globin genes.A 3-bp deletion in the HBS1L-MYB intergenic region on chromosome 6q23 is associated with HbF expressionFetal hemoglobin reactivation and cell engineering in the treatment of sickle cell anemia.Sickle cell disease: old discoveries, new concepts, and future promise.Intergenic variants of HBS1L-MYB are responsible for a major quantitative trait locus on chromosome 6q23 influencing fetal hemoglobin levels in adults.What influences Hb fetal production in adulthood?The genomics of new drugs in sickle cell disease.A genome-wide search replicates evidence of a quantitative trait locus for circulating angiotensin I-converting enzyme (ACE) unlinked to the ACE gene.Transgenic knockout mice exclusively expressing human hemoglobin S after transfer of a 240-kb betas-globin yeast artificial chromosome: A mouse model of sickle cell anemiaDNA polymorphisms at the BCL11A, HBS1L-MYB, and beta-globin loci associate with fetal hemoglobin levels and pain crises in sickle cell disease.Control of fetal hemoglobin: new insights emerging from genomics and clinical implications.Fetal globin gene inducers: novel agents and new potential.A randomized phase I/II trial of HQK-1001, an oral fetal globin gene inducer, in β-thalassaemia intermedia and HbE/β-thalassaemia.Modifier genes in Mendelian disorders: the example of hemoglobin disorders.Genomic polymorphisms in sickle cell disease: implications for clinical diversity and treatment.The search for genetic modifiers of disease severity in the β-hemoglobinopathies.Zinc fingers and homeoboxes family in human diseases.Therapeutic fetal-globin inducers reduce transcriptional repression in hemoglobinopathy erythroid progenitors through distinct mechanisms.Homozygosity for a rare beta 0-thalassemia mutation [frameshift codons 25/26 (+T)] causes beta-thalassemia intermedia in an Iranian family.A post-transcriptional process contributes to efficient gamma-globin gene silencing in definitive erythroid cells.Genetics of Hb F/F cell variance in adults and heterocellular hereditary persistence of fetal hemoglobin.Lack of association of G779A ZHX-2 gene variant with HbF levels in β-thalassemia major.β-Globin gene cluster polymorphisms are strongly associated with severity of HbE/β0-thalassemia
P2860
Q21266618-429A25AF-0BB1-40D7-86A8-9632E26FA86DQ24293797-712BA53A-2DD6-4D33-85AF-14D5344459A0Q33332124-B717B6A2-1940-475F-A30F-54AE4ACBB9DCQ33369073-1431510C-97C2-4DE1-B9DD-2406569AE961Q33791764-138C32CE-FD16-4161-ABC1-2E470FA455EDQ34580060-A601DCE5-5EC7-4DE8-B511-2A5C55E65E6EQ35001653-5004F9C6-0CFE-49DD-86FF-C2C4EE6A732EQ35683885-E319BEDA-1182-4E28-93FB-4F297A24F03EQ35723452-82D182E7-635F-4BF3-B249-E5DC9E287C45Q36090188-41767355-F7E2-4EC2-8AC6-DBE25C0D09E6Q36153499-2DDF2D19-32DC-48B4-BF10-774F5BDECBBCQ36596719-D15D4A5B-C561-40D6-9218-017DDC03D968Q36742211-0E4D1D00-1F79-4569-AE1C-67ECF2FA84E9Q36757616-0D3351FA-A092-48AB-BB19-41E5C0E7CE7AQ36800496-DC2FC036-F031-4AB0-95E0-88F17139B581Q37379477-9852677C-0C54-407F-83E2-1CDD480B03CFQ37552428-C90502E3-F01B-470F-95F9-6D7729BAE9D2Q37674785-833DF415-BE4C-41CA-B654-D51B6CDF8812Q37805602-062E9BB8-7059-4503-B303-8CB385797B5CQ37810126-3B3EAC74-1B1D-434D-82BA-017CF9F538B1Q38048766-D88D9CCB-90EE-4484-8241-082D3CDE3E33Q38413057-7E2D9CFC-4848-4D16-A90D-87CC6BC78AF8Q38816924-9C4EE31C-800A-4195-8013-0FD1FA3D8AF6Q46703525-CA002B72-4026-435F-A62B-A3AA2ED559FFQ46919881-858353E7-6354-4F8C-AC25-4F6139672B7AQ50851801-CF62EBA0-8598-45F6-9283-09CF05487CE3Q55054108-0A3E3FF3-2F07-4455-9FB9-5B95DA77A4B0Q57318845-AA37BB86-B5BA-4184-B156-3B90FDD186A4
P2860
Haplotype mapping of a major quantitative-trait locus for fetal hemoglobin production, on chromosome 6q23.
description
1998 nî lūn-bûn
@nan
1998 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
1998 թվականի հունիսին հրատարակված գիտական հոդված
@hy
1998年の論文
@ja
1998年論文
@yue
1998年論文
@zh-hant
1998年論文
@zh-hk
1998年論文
@zh-mo
1998年論文
@zh-tw
1998年论文
@wuu
name
Haplotype mapping of a major q ...... roduction, on chromosome 6q23.
@ast
Haplotype mapping of a major q ...... roduction, on chromosome 6q23.
@en
Haplotype mapping of a major q ...... roduction, on chromosome 6q23.
@nl
type
label
Haplotype mapping of a major q ...... roduction, on chromosome 6q23.
@ast
Haplotype mapping of a major q ...... roduction, on chromosome 6q23.
@en
Haplotype mapping of a major q ...... roduction, on chromosome 6q23.
@nl
prefLabel
Haplotype mapping of a major q ...... roduction, on chromosome 6q23.
@ast
Haplotype mapping of a major q ...... roduction, on chromosome 6q23.
@en
Haplotype mapping of a major q ...... roduction, on chromosome 6q23.
@nl
P2093
P2860
P356
P1476
Haplotype mapping of a major q ...... roduction, on chromosome 6q23.
@en
P2093
P2860
P304
P356
10.1086/301859
P407
P577
1998-06-01T00:00:00Z