Frap, FKBP12 rapamycin-associated protein, is a candidate gene for the plasmacytoma resistance locus Pctr2 and can act as a tumor suppressor gene
about
DEPTOR is an mTOR inhibitor frequently overexpressed in multiple myeloma cells and required for their survivalPreclinical validation of interleukin 6 as a therapeutic target in multiple myelomaMndal, a new interferon-inducible family member, is highly polymorphic, suppresses cell growth, and may modify plasmacytoma susceptibilityConstitutive reductions in mTOR alter cell size, immune cell development, and antibody production.IL-6 and MYC collaborate in plasma cell tumor formation in mice.Global gene expression profiling in mouse plasma cell tumor precursor and bystander cells reveals potential intervention targets for plasma cell neoplasia.Brain tumor susceptibility: the role of genetic factors and uses of mouse models to unravel risk.Loci controlling lymphocyte production of interferon c after alloantigen stimulation in vitro and their co-localization with genes controlling lymphocyte infiltration of tumors and tumor susceptibility.Pharmacogenomics: a new paradigm to personalize treatments in nephrology patients.TORC1 and class I HDAC inhibitors synergize to suppress mature B cell neoplasms.Waldenström macroglobulinemia: clinical and immunological aspects, natural history, cell of origin, and emerging mouse modelsTherapeutic potential of targeting IRES-dependent c-myc translation in multiple myeloma cells during ER stress.DEPTOR is linked to a TORC1-p21 survival proliferation pathway in multiple myeloma cells.
P2860
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P2860
Frap, FKBP12 rapamycin-associated protein, is a candidate gene for the plasmacytoma resistance locus Pctr2 and can act as a tumor suppressor gene
description
2003 nî lūn-bûn
@nan
2003 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
Frap, FKBP12 rapamycin-associa ...... act as a tumor suppressor gene
@ast
Frap, FKBP12 rapamycin-associa ...... act as a tumor suppressor gene
@en
Frap, FKBP12 rapamycin-associa ...... act as a tumor suppressor gene
@nl
type
label
Frap, FKBP12 rapamycin-associa ...... act as a tumor suppressor gene
@ast
Frap, FKBP12 rapamycin-associa ...... act as a tumor suppressor gene
@en
Frap, FKBP12 rapamycin-associa ...... act as a tumor suppressor gene
@nl
prefLabel
Frap, FKBP12 rapamycin-associa ...... act as a tumor suppressor gene
@ast
Frap, FKBP12 rapamycin-associa ...... act as a tumor suppressor gene
@en
Frap, FKBP12 rapamycin-associa ...... act as a tumor suppressor gene
@nl
P2093
P2860
P356
P1476
Frap, FKBP12 rapamycin-associa ...... act as a tumor suppressor gene
@en
P2093
Beverly A Mock
Douglas R Lowy
Edward S Ramsay
John Scott
Shuling Zhang
Valery Bliskovsky
Wendy DuBois
Xiaolan Qian
P2860
P304
14982-14987
P356
10.1073/PNAS.2431627100
P407
P577
2003-11-21T00:00:00Z