RAFT1 phosphorylation of the translational regulators p70 S6 kinase and 4E-BP1 - Wikidata - wikimedia - TriplyDB

RAFT1 phosphorylation of the translational regulators p70 S6 kinase and 4E-BP1

RAFT1 phosphorylation of the translational regulators p70 S6 kinase and 4E-BP1

http://www.wikidata.org/entity/Q24682697

about

Negative regulation of protein translation by mitogen-activated protein kinase-interacting kinases 1 and 2 The mTOR/PI3K and MAPK pathways converge on eIF4B to control its phosphorylation and activity CCL5-mediated T-cell chemotaxis involves the initiation of mRNA translation through mTOR/4E-BP1 DEPTOR is an mTOR inhibitor frequently overexpressed in multiple myeloma cells and required for their survival Reassessment of the role of FKBP38 in the Rheb/mTORC1 pathway PRAS40 is a target for mammalian target of rapamycin complex 1 and is required for signaling downstream of this complex GOLPH3 modulates mTOR signalling and rapamycin sensitivity in cancer Distinct signaling events downstream of mTOR cooperate to mediate the effects of amino acids and insulin on initiation factor 4E-binding proteins.Signaling by target of rapamycin proteins in cell growth control Insulin-stimulated phosphorylation of lipin mediated by the mammalian target of rapamycin.Insulin-stimulated kinase from rat fat cells that phosphorylates initiation factor 4E-binding protein 1 on the rapamycin-insensitive site (serine-111)Fibronectin controls cap-dependent translation through beta1 integrin and eukaryotic initiation factors 4 and 2 coordinated pathways Regulation of mTOR and cell growth in response to energy stress by REDD1.The PI3K-PDK1 connection: more than just a road to PKB Nutrients suppress phosphatidylinositol 3-kinase/Akt signaling via raptor-dependent mTOR-mediated insulin receptor substrate 1 phosphorylation Regulation of elongation factor 2 kinase by p90(RSK1) and p70 S6 kinase.Elucidating TOR signaling and rapamycin action: lessons from Saccharomyces cerevisiae.The FKBP12-rapamycin-associated protein (FRAP) is a CLIP-170 kinase Protein kinase C phosphorylates ribosomal protein S6 kinase betaII and regulates its subcellular localization.Multiple mechanisms control phosphorylation of PHAS-I in five (S/T)P sites that govern translational repression Phosphorylation of the cap-binding protein eukaryotic translation initiation factor 4E by protein kinase Mnk1 in vivo Disruption of the mouse mTOR gene leads to early postimplantation lethality and prohibits embryonic stem cell development mTOR is essential for growth and proliferation in early mouse embryos and embryonic stem cells Functional interaction between RAFT1/FRAP/mTOR and protein kinase cdelta in the regulation of cap-dependent initiation of translation Regulation of 4E-BP1 phosphorylation: a novel two-step mechanism S6K1(-/-)/S6K2(-/-) mice exhibit perinatal lethality and rapamycin-sensitive 5'-terminal oligopyrimidine mRNA translation and reveal a mitogen-activated protein kinase-dependent S6 kinase pathway mTOR-dependent activation of the transcription factor TIF-IA links rRNA synthesis to nutrient availability Regulating mammalian target of rapamycin to tune vaccination-induced CD8(+) T cell responses for tumor immunity mTOR signaling in growth control and disease The proline-rich Akt substrate of 40 kDa (PRAS40) is a physiological substrate of mammalian target of rapamycin complex 1 Characterization of Rictor phosphorylation sites reveals direct regulation of mTOR complex 2 by S6K1 The TSC1-TSC2 complex: a molecular switchboard controlling cell growth Protein phosphatase 2A interacts with the 70-kDa S6 kinase and is activated by inhibition of FKBP12-rapamycinassociated protein Hypoxia regulates TSC1/2-mTOR signaling and tumor suppression through REDD1-mediated 14-3-3 shuttling A MAP4 kinase related to Ste20 is a nutrient-sensitive regulator of mTOR signalling Neurabin is a synaptic protein linking p70 S6 kinase and the neuronal cytoskeleton Autophagy in Chronic Kidney Diseases Novel targeting of phosphatidylinositol 3-kinase and mammalian target of rapamycin in renal cell carcinoma mTOR Signaling in Protein Translation Regulation: Implications in Cancer Genesis and Therapeutic Interventions Targeted therapies in development for non-small cell lung cancer

P2860

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P2860

RAFT1 phosphorylation of the translational regulators p70 S6 kinase and 4E-BP1

http://www.wikidata.org/entity/Q24682697

description

1998 nî lūn-bûn

@nan

1998 թուականի Փետրուարին հրատարակուած գիտական յօդուած

@hyw

1998 թվականի փետրվարին հրատարակված գիտական հոդված

@hy

1998年の論文

@ja

1998年論文

@yue

1998年論文

@zh-hant

1998年論文

@zh-hk

1998年論文

@zh-mo

1998年論文

@zh-tw

1998年论文

@wuu

name

RAFT1 phosphorylation of the translational regulators p70 S6 kinase and 4E-BP1

@ast

RAFT1 phosphorylation of the translational regulators p70 S6 kinase and 4E-BP1

@en

RAFT1 phosphorylation of the translational regulators p70 S6 kinase and 4E-BP1

@nl

type

label

RAFT1 phosphorylation of the translational regulators p70 S6 kinase and 4E-BP1

@ast

RAFT1 phosphorylation of the translational regulators p70 S6 kinase and 4E-BP1

@en

RAFT1 phosphorylation of the translational regulators p70 S6 kinase and 4E-BP1

@nl

prefLabel

RAFT1 phosphorylation of the translational regulators p70 S6 kinase and 4E-BP1

@ast

RAFT1 phosphorylation of the translational regulators p70 S6 kinase and 4E-BP1

@en

RAFT1 phosphorylation of the translational regulators p70 S6 kinase and 4E-BP1

@nl

P1433

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P2860

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P1433

Proceedings of the National Academy of Sciences of the United States of America

P1476

RAFT1 phosphorylation of the translational regulators p70 S6 kinase and 4E-BP1

@en

P2093

P E Burnett

http://www.w3.org/2001/XMLSchema#string

R K Barrow

http://www.w3.org/2001/XMLSchema#string

S H Snyder

http://www.w3.org/2001/XMLSchema#string

P2860

Insulin-dependent stimulation of protein synthesis by phosphorylation of a regulator of 5'-cap function

Dual requirement for a newly identified phosphorylation site in p70s6k

Site-directed mutagenesis by overlap extension using the polymerase chain reaction

TOR controls translation initiation and early G1 progression in yeast

PIK-related kinases: DNA repair, recombination, and cell cycle checkpoints.

Rapamycin-FKBP specifically blocks growth-dependent activation of and signaling by the 70 kd S6 protein kinases

A mammalian protein targeted by G1-arresting rapamycin-receptor complex

RAFT1: a mammalian protein that binds to FKBP12 in a rapamycin-dependent fashion and is homologous to yeast TORs

Binding of the inward rectifier K+ channel Kir 2.3 to PSD-95 is regulated by protein kinase A phosphorylation

Isolation of a protein target of the FKBP12-rapamycin complex in mammalian cells

P304

1432-1437

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P3181

789539

http://www.w3.org/2001/XMLSchema#string

P356

10.1073/PNAS.95.4.1432

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P407

P433

4

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P478

95

http://www.w3.org/2001/XMLSchema#string

P50

David M Sabatini

P577

1998-02-01T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

235609494

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P698

9465032

http://www.w3.org/2001/XMLSchema#string

P921

phosphorylation

P932

19032

http://www.w3.org/2001/XMLSchema#string