Identification of thalidomide-specific transcriptomics and proteomics signatures during differentiation of human embryonic stem cells. - Wikidata - wikimedia - TriplyDB

Identification of thalidomide-specific transcriptomics and proteomics signatures during differentiation of human embryonic stem cells.

Identification of thalidomide-specific transcriptomics and proteomics signatures during differentiation of human embryonic stem cells.

http://www.wikidata.org/entity/Q34406463

about

Pomalidomide is nonteratogenic in chicken and zebrafish embryos and nonneurotoxic in vitro Thalidomide-induced teratogenesis: history and mechanisms High-Dose Fluoride Impairs the Properties of Human Embryonic Stem Cells via JNK Signaling Definition of transcriptome-based indices for quantitative characterization of chemically disturbed stem cell development: introduction of the STOP-Toxukn and STOP-Toxukk tests.A method for human teratogen detection by geometrically confined cell differentiation and migration A transcriptome-based classifier to identify developmental toxicants by stem cell testing: design, validation and optimization for histone deacetylase inhibitors Human Pluripotent Stem Cell Based Developmental Toxicity Assays for Chemical Safety Screening and Systems Biology Data Generation Transcriptional and metabolic adaptation of human neurons to the mitochondrial toxicant MPP(+)Decreased neural precursor cell pool in NADPH oxidase 2-deficiency: From mouse brain to neural differentiation of patient derived iPSC.Profiling of drugs and environmental chemicals for functional impairment of neural crest migration in a novel stem cell-based test battery Differences in the Early Development of Human and Mouse Embryonic Stem Cells.Transcriptomics analysis of early embryonic stem cell differentiation under osteoblast culture conditions: Applications for detection of developmental toxicity.The Role of mGluR Copy Number Variation in Genetic and Environmental Forms of Syndromic Autism Spectrum Disorder Comparison of a teratogenic transcriptome-based predictive test based on human embryonic versus inducible pluripotent stem cells.Assessment of Protein Binding of 5-Hydroxythalidomide Bioactivated in Humanized Mice with Human P450 3A-Chromosome or Hepatocytes by Two-Dimensional Electrophoresis/Accelerator Mass Spectrometry.Design principles of concentration-dependent transcriptome deviations in drug-exposed differentiating stem cells.Systems pharmacology modeling: an approach to improving drug safety.Epigenetics and transcriptomics to detect adverse drug effects in model systems of human development.Human embryonic stem cell-derived test systems for developmental neurotoxicity: a transcriptomics approach.Thalidomide induces apoptosis in undifferentiated human induced pluripotent stem cells.Embryonic stem cells and the next generation of developmental toxicity testing.Prenatal exposure to environmental factors and congenital limb defects.Neuronal developmental gene and miRNA signatures induced by histone deacetylase inhibitors in human embryonic stem cells.Prospects and Frontiers of Stem Cell Toxicology Gene Expression Regulation and Pathway Analysis After Valproic Acid and Carbamazepine Exposure in a Human Embryonic Stem Cell-Based Neurodevelopmental Toxicity Assay.Critical region within 22q11.2 linked to higher rate of autism spectrum disorder.Modern methodologies and tools for human hazard assessment of chemicals Functional cardiotoxicity assessment of cosmetic compounds using human-induced pluripotent stem cell-derived cardiomyocytes.Developmental neurotoxicity testing with human embryonic stem cell-derived in vitro systems: the novel FP7 ESNATS tests are available.Monocrotophos in Gandaman village: India school lunch deaths and need for improved toxicity testing.Teratogen screening with human pluripotent stem cells

P2860

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P2860

Identification of thalidomide-specific transcriptomics and proteomics signatures during differentiation of human embryonic stem cells.

http://www.wikidata.org/entity/Q34406463

description

2012 nî lūn-bûn

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2012 թուականի Օգոստոսին հրատարակուած գիտական յօդուած

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2012 թվականի օգոստոսին հրատարակված գիտական հոդված

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Identification of thalidomide- ...... of human embryonic stem cells.

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Identification of thalidomide- ...... of human embryonic stem cells.

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Identification of thalidomide- ...... of human embryonic stem cells.

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Identification of thalidomide- ...... of human embryonic stem cells.

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Identification of thalidomide- ...... of human embryonic stem cells.

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Identification of thalidomide- ...... of human embryonic stem cells.

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Identification of thalidomide- ...... of human embryonic stem cells.

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Diana Hildebrand

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Hartmut Schlüter

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Johannes Winkler

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John Antonydas Gaspar

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Karola Lehmann

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Kesavan Meganathan

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Maria Trusch

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Smita Jagtap

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Vilas Wagh

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P2860

Evaluation of 60 chemicals in a preliminary developmental toxicity test.

Identification of a primary target of thalidomide teratogenicity

DAVID: Database for Annotation, Visualization, and Integrated Discovery

PAK4 kinase is essential for embryonic viability and for proper neuronal development

Defects and disabilities of thalidomide children

The Hand1 and Hand2 transcription factors regulate expansion of the embryonic cardiac ventricles in a gene dosage-dependent manner

Glutathione transferases

Safety profile of thalidomide after 53 weeks of oral administration in beagle dogs.

Classical proteomics: two-dimensional electrophoresis/MALDI mass spectrometry.

Teratogen update: thalidomide: a review, with a focus on ocular findings and new potential uses.

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