Talin contains three actin-binding sites each of which is adjacent to a vinculin-binding site.
about
Talin contains a C-terminal calpain2 cleavage site important in focal adhesion dynamicsLayilin, a novel talin-binding transmembrane protein homologous with C-type lectins, is localized in membrane rufflesLayilin, a novel integral membrane protein, is a hyaluronan receptorActivation of a vinculin-binding site in the talin rod involves rearrangement of a five-helix bundleThe integrin-actin connection, an eternal love affairPriming by chemokines restricts lateral mobility of the adhesion receptor LFA-1 and restores adhesion to ICAM-1 nano-aggregates on human mature dendritic cellsVinculin controls talin engagement with the actomyosin machinery.The structure of the C-terminal actin-binding domain of talinStructural Determinants of Integrin Binding to the Talin RodThe Structure of an Interdomain Complex That Regulates Talin ActivityThe domain structure of talin: Residues 1815-1973 form a five-helix bundle containing a cryptic vinculin-binding siteCentral Region of Talin Has a Unique Fold That Binds Vinculin and ActinIntermolecular versus intramolecular interactions of the vinculin binding site 33 of talinRIAM and Vinculin Binding to Talin Are Mutually Exclusive and Regulate Adhesion Assembly and TurnoverSla2p is associated with the yeast cortical actin cytoskeleton via redundant localization signals.Integrins in cell migration--the actin connection.Investigating complexity of protein-protein interactions in focal adhesions.Vinculin controls focal adhesion formation by direct interactions with talin and actin.Molecular dynamics study of talin-vinculin binding.Structural model and functional significance of pH-dependent talin-actin binding for focal adhesion remodeling.Clustering of alpha(5)beta(1) integrins determines adhesion strength whereas alpha(v)beta(3) and talin enable mechanotransductionTalin1 is critical for force-dependent reinforcement of initial integrin-cytoskeleton bonds but not tyrosine kinase activationProtein-lipid interactions: correlation of a predictive algorithm for lipid-binding sites with three-dimensional structural dataHow force might activate talin's vinculin binding sites: SMD reveals a structural mechanism.Transcription profiling provides insights into gene pathways involved in horn and scurs development in cattleTalin regulates moesin-NHE-1 recruitment to invadopodia and promotes mammary tumor metastasis.Talin contains three similar vinculin-binding sites predicted to form an amphipathic helixDiminished thrombogenic responses by deletion of the Podocalyxin Gene in mouse megakaryocytes.Studies on the morphology and spreading of human endothelial cells define key inter- and intramolecular interactions for talin1.New isoform-specific monoclonal antibodies reveal different sub-cellular localisations for talin1 and talin2.The talin dimer structure orientation is mechanically regulated.Vinculin activation is necessary for complete talin bindingMicrotubule-dependent modulation of adhesion complex composition.Talin 2 is a large and complex gene encoding multiple transcripts and protein isoformsDrosophila melanogaster myosin-18 represents a highly divergent motor with actin tethering propertiesNew insights into vinculin function and regulation.Subcellular localization of talin is regulated by inter-domain interactionsWdr1-Dependent Actin Reorganization in Platelet Activation.The I/LWEQ module: a conserved sequence that signifies F-actin binding in functionally diverse proteins from yeast to mammalsα-actinin is required for the proper assembly of Z-disk/focal-adhesion-like structures and for efficient locomotion in Caenorhabditis elegans.
P2860
Q21134703-428086E2-4DDF-4979-B867-B9893F1F3A2AQ22004003-983CB949-9EF1-4F30-855A-22B66E97A505Q24291106-AA8DB110-9E08-430B-B232-287780C625ABQ24563216-29D24138-3F52-4F75-B3D0-F069A0DEA479Q24676735-4AB18C21-54A6-40ED-A7BF-568248E7CA9DQ27324034-15BFBE24-B28B-4BD6-A536-E8D9E1F471EBQ27342876-87BAF5F4-B270-4303-B4C1-9E3C9EBD96C7Q27649413-B7D30B52-32DB-4964-810A-6CF2A140BB36Q27653581-710A8CAD-FE75-477A-9C52-E1B3B52A9204Q27654202-8EEC942F-6481-439F-84CD-2D74217B2220Q27660586-DBF96C21-D106-4AE9-9DBB-C7F99F30BB09Q27663253-A13DC892-79C3-4BA5-AE27-61978FAEBFFAQ27666262-75744887-2DE9-44E3-9A78-D12854E15158Q27676229-2969A8F1-49D9-4D92-8B4D-AE792BB69085Q27939303-CCF5FE69-114F-4D68-B7BC-E9D1BC2C2D99Q30437361-9DCB0B50-8D50-4F0E-8157-7531687A1896Q30438896-C9AEA72D-2629-40E8-BD2C-DDFB97C5483AQ30441610-3ED68122-EEA3-4833-B558-29A38E0CE689Q30482837-69673946-BD90-4B9E-9479-527A1385E5D0Q30483435-9A64F9C0-AE19-4695-AA77-64C72550D993Q30490566-9967333B-C542-41C6-9A79-4C9D0D29F660Q31018295-7FC7D9DC-9E86-4168-8EA6-5AD9E59023FAQ31035306-DD9F888A-9289-412C-90D9-CD3B47F7E85BQ33320176-68E46433-CC69-4FBC-B7F4-535C2B522F7CQ33600440-A6E7CBDE-C1BD-4FDF-8FC9-6135C5452F22Q33731231-59BE7291-BF8D-464D-858A-58FE874709ECQ33866886-69D4B67C-D810-4BB1-B4D1-6D3234D92C11Q34053437-0E94218A-9A72-4FAF-AD5C-FB67E45E3BE9Q34218072-A3E38407-5741-407A-8622-A96A38E26CF7Q34252107-0D2AD45B-E9B9-4B34-99F2-A3E4C68026BCQ34424133-BFC7967F-EE92-4700-B9CF-50529580052DQ34494457-CB7A4A1A-93CC-4510-9E40-20EA21F0C7A1Q34744466-D4C89971-4B6B-4EEA-8CAF-271DCD66299AQ34946043-E92E1394-9B42-4D98-9125-A17D7FC41026Q35065264-19629246-7F13-4AFC-B865-5146A6AAE03AQ35591684-D20898B3-A932-43D2-B609-17DB1A9D29AEQ35922268-30AFCCC9-850F-412B-8807-EEA1C6BC524EQ36132692-B995D5A5-E0A3-4E2E-9A33-324CD691E41AQ36155573-205D90A5-7A94-4616-AEAF-C385845D490FQ36231028-100D7B9B-FE4F-4D18-BC98-2D6E449BC737
P2860
Talin contains three actin-binding sites each of which is adjacent to a vinculin-binding site.
description
1996 nî lūn-bûn
@nan
1996 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
1996 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
1996年の論文
@ja
1996年論文
@yue
1996年論文
@zh-hant
1996年論文
@zh-hk
1996年論文
@zh-mo
1996年論文
@zh-tw
1996年论文
@wuu
name
Talin contains three actin-bin ...... nt to a vinculin-binding site.
@ast
Talin contains three actin-bin ...... nt to a vinculin-binding site.
@en
Talin contains three actin-bin ...... nt to a vinculin-binding site.
@nl
type
label
Talin contains three actin-bin ...... nt to a vinculin-binding site.
@ast
Talin contains three actin-bin ...... nt to a vinculin-binding site.
@en
Talin contains three actin-bin ...... nt to a vinculin-binding site.
@nl
prefLabel
Talin contains three actin-bin ...... nt to a vinculin-binding site.
@ast
Talin contains three actin-bin ...... nt to a vinculin-binding site.
@en
Talin contains three actin-bin ...... nt to a vinculin-binding site.
@nl
P2093
P1476
Talin contains three actin-bin ...... nt to a vinculin-binding site.
@en
P2093
Critchley DR
Gilmore AP
Hemmings L
Trevithick JE
P304
P407
P478
109 ( Pt 11)
P577
1996-11-01T00:00:00Z