Endosomal processing limits gene transfer to polarized airway epithelia by adeno-associated virus.
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Adeno-associated virus type 6 (AAV6) vectors mediate efficient transduction of airway epithelial cells in mouse lungs compared to that of AAV2 vectorsAdeno-associated virus type 2-mediated gene transfer: role of cellular FKBP52 protein in transgene expressionEfficient transduction of vascular endothelial cells with recombinant adeno-associated virus serotype 1 and 5 vectorsCell-type-specific characteristics modulate the transduction efficiency of adeno-associated virus type 2 and restrain infection of endothelial cells.Adeno-associated virus for cystic fibrosis gene therapyVirus strategies for passing the nuclear envelope barrierA capsid-encoded PPxY-motif facilitates adenovirus entryGene therapy for hemophiliaBAAV transcytosis requires an interaction with beta-1-4 linked- glucosamine and gp96Gene therapy delivery systems for enhancing viral and nonviral vectors for cardiac diseases: current concepts and future applications.Green fluorescent protein-tagged adeno-associated virus particles allow the study of cytosolic and nuclear trafficking.Mutagenesis of adeno-associated virus type 2 capsid protein VP1 uncovers new roles for basic amino acids in trafficking and cell-specific transduction.Quantitative 3D tracing of gene-delivery viral vectors in human cells and animal tissues.Generation of novel AAV variants by directed evolution for improved CFTR delivery to human ciliated airway epithelium.Molecular evolution of adeno-associated virus for enhanced glial gene delivery.Limitations of encapsidation of recombinant self-complementary adeno-associated viral genomes in different serotype capsids and their quantitationEndocytosis and nuclear trafficking of adeno-associated virus type 2 are controlled by rac1 and phosphatidylinositol-3 kinase activation.Systemic Trans-splicing adeno-associated viral delivery efficiently transduces the heart of adult mdx mouse, a model for duchenne muscular dystrophyHigh-efficiency transduction of the mouse retina by tyrosine-mutant AAV serotype vectorsStrategies to modulate immune responses: a new frontier for gene therapyEvidence for the failure of adeno-associated virus serotype 5 to package a viral genome > or = 8.2 kb.Synthesis and inhibition study on tripeptide inhibitor modified poly(L-lysine) dendrimers.Complement yourself: Transcomplementation rescues partially folded mutant proteins.Vector serotype screening for use in ovine perinatal lung gene therapy.Optimized adeno-associated virus (AAV)-protein phosphatase-5 helper viruses for efficient liver transduction by single-stranded AAV vectors: therapeutic expression of factor IX at reduced vector doses.Adeno-associated virus type 2-mediated gene transfer: altered endocytic processing enhances transduction efficiency in murine fibroblastsVesicular stomatitis virus G-pseudotyped lentivirus vectors mediate efficient apical transduction of polarized quiescent primary alveolar epithelial cells.Hoechst increases adeno-associated virus-mediated transgene expression in airway epithelia by inducing the cytomegalovirus promoterInvolvement of cellular double-stranded DNA break binding proteins in processing of the recombinant adeno-associated virus genome.AAV exploits subcellular stress associated with inflammation, endoplasmic reticulum expansion, and misfolded proteins in models of cystic fibrosis.Cell-Mediated Immunity to AAV Vectors, Evolving Concepts and Potential Solutions.Virus-mediated transduction of murine retina with adeno-associated virus: effects of viral capsid and genome size.Proteasome inhibitors enhance gene delivery by AAV virus vectors expressing large genomes in hemophilia mouse and dog models: a strategy for broad clinical application.Efficient generation and amplification of high-capacity adeno-associated virus/adenovirus hybrid vectors.High-efficiency transduction and correction of murine hemophilia B using AAV2 vectors devoid of multiple surface-exposed tyrosines.Pseudotyped AAV vector-mediated gene transfer in a human fetal trachea xenograft model: implications for in utero gene therapy for cystic fibrosis.LDLR-Gene therapy for familial hypercholesterolaemia: problems, progress, and perspectivesAdeno-associated virus type 2-mediated gene transfer: role of cellular T-cell protein tyrosine phosphatase in transgene expression in established cell lines in vitro and transgenic mice in vivo.Efficient transgene reconstitution with hybrid dual AAV vectors carrying the minimized bridging sequencesActivation of the cellular unfolded protein response by recombinant adeno-associated virus vectors.
P2860
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P2860
Endosomal processing limits gene transfer to polarized airway epithelia by adeno-associated virus.
description
2000 nî lūn-bûn
@nan
2000 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2000 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2000年の論文
@ja
2000年論文
@yue
2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
@zh-tw
2000年论文
@wuu
name
Endosomal processing limits ge ...... lia by adeno-associated virus.
@ast
Endosomal processing limits ge ...... lia by adeno-associated virus.
@en
Endosomal processing limits ge ...... lia by adeno-associated virus.
@nl
type
label
Endosomal processing limits ge ...... lia by adeno-associated virus.
@ast
Endosomal processing limits ge ...... lia by adeno-associated virus.
@en
Endosomal processing limits ge ...... lia by adeno-associated virus.
@nl
prefLabel
Endosomal processing limits ge ...... lia by adeno-associated virus.
@ast
Endosomal processing limits ge ...... lia by adeno-associated virus.
@en
Endosomal processing limits ge ...... lia by adeno-associated virus.
@nl
P2860
P50
P356
P1476
Endosomal processing limits ge ...... elia by adeno-associated virus
@en
P2860
P304
P356
10.1172/JCI8317
P407
P577
2000-06-01T00:00:00Z