Pharmacological inhibition and genetic knockdown of exchange protein directly activated by cAMP 1 reduce pancreatic cancer metastasis in vivo.

Pharmacological inhibition and genetic knockdown of exchange protein directly activated by cAMP 1 reduce pancreatic cancer metastasis in vivo.

Item
http://www.wikidata.org/entity/Q34447181
Role of EPAC in cAMP-Mediated Actions in Adrenocortical CellsExchange protein directly activated by cAMP encoded by the mammalian rapgef3 gene: Structure, function and therapeuticsBiochemical and pharmacological characterizations of ESI-09 based EPAC inhibitors: defining the ESI-09 "therapeutic window".The pleiotropic role of exchange protein directly activated by cAMP 1 (EPAC1) in cancer: implications for therapeutic intervention.Structure-Activity Relationship Studies of Substituted 2-(Isoxazol-3-yl)-2-oxo-N'-phenyl-acetohydrazonoyl Cyanide Analogues: Identification of Potent Exchange Proteins Directly Activated by cAMP (EPAC) Antagonists.Functionalized N,N-Diphenylamines as Potent and Selective EPAC2 Inhibitors.Identification of Extracellular Segments by Mass Spectrometry Improves Topology Prediction of Transmembrane Proteins.Epac2a-null mice exhibit obesity-prone nature more susceptible to leptin resistance.Loss of phosphodiesterase 4D mediates acquired triapine resistance via Epac-Rap1-Integrin signaling.EPAC1 overexpression is a prognostic marker and its inhibition shows promising therapeutic potential for gastric cancer.Exchange proteins directly activated by cAMP (EPACs): Emerging therapeutic targets.Epac1 links prostaglandin E2 to β-catenin-dependent transcription during epithelial-to-mesenchymal transition.A cell-based, quantitative and isoform-specific assay for exchange proteins directly activated by cAMP.An Orally Active Epac Inhibitor Reverses Mechanical Allodynia and Loss of Intraepidermal Nerve Fibers \iIn A Mouse Model of Chemotherapy-Induced Peripheral Neuropathy.Identification of novel 2-(benzo[d]isoxazol-3-yl)-2-oxo-N-phenylacetohydrazonoyl cyanide analoguesas potent EPAC antagonists.Intracellular cAMP Sensor EPAC: Physiology, Pathophysiology, and Therapeutics Development.
P2860

Pharmacological inhibition and genetic knockdown of exchange protein directly activated by cAMP 1 reduce pancreatic cancer metastasis in vivo.

Item
http://www.wikidata.org/entity/Q34447181
description
2014 nî lūn-bûn
@nan
2014 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2014 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
name
Pharmacological inhibition and ...... tic cancer metastasis in vivo.
@ast
Pharmacological inhibition and ...... tic cancer metastasis in vivo.
@en
Pharmacological inhibition and ...... tic cancer metastasis in vivo.
@nl
type
label
Pharmacological inhibition and ...... tic cancer metastasis in vivo.
@ast
Pharmacological inhibition and ...... tic cancer metastasis in vivo.
@en
Pharmacological inhibition and ...... tic cancer metastasis in vivo.
@nl
prefLabel
Pharmacological inhibition and ...... tic cancer metastasis in vivo.
@ast
Pharmacological inhibition and ...... tic cancer metastasis in vivo.
@en
Pharmacological inhibition and ...... tic cancer metastasis in vivo.
@nl
P1433
P1476
P2093
P2860
P304
P31
P356
P433
P478
P577
P5875
P698
P921
P932
P356
P1433
P1476
Pharmacological inhibition and ...... tic cancer metastasis in vivo.
@en
P2093
P2860
P304
P31
P356
P433
P478
P577
P5875
P698
P921
P932