Differential signaling of cyclic AMP: opposing effects of exchange protein directly activated by cyclic AMP and cAMP-dependent protein kinase on protein kinase B activation.
about
Epac: A new cAMP-binding protein in support of glucagon-like peptide-1 receptor-mediated signal transduction in the pancreatic beta-cellRap1a is a key regulator of fibroblast growth factor 2-induced angiogenesis and together with Rap1b controls human endothelial cell functionscAMP response element binding protein (CREB) activates transcription via two distinct genetic elements of the human glucose-6-phosphatase geneRegulatory T-Cell-Mediated Suppression of Conventional T-Cells and Dendritic Cells by Different cAMP Intracellular PathwaysTargeting protein-protein interactions in complexes organized by A kinase anchoring proteinsS1PR2 links germinal center confinement and growth regulationThe neurobiology of tetrahydrobiopterin biosynthesis: a model for regulation of GTP cyclohydrolase I gene transcription within nigrostriatal dopamine neuronsCell physiology of cAMP sensor Epac.FRET measurements of intracellular cAMP concentrations and cAMP analog permeability in intact cellsThe microtubule associated protein syntabulin is required for glucose-stimulated and cAMP-potentiated insulin secretionCharacterization of thyrotropin receptor antibody-induced signaling cascadesProtein kinase A and B-Raf mediate extracellular signal-regulated kinase activation by thyrotropinEpac1 is upregulated during neointima formation and promotes vascular smooth muscle cell migrationcAMP stimulates apical exocytosis of the renal Na(+)-K(+)-2Cl(-) cotransporter NKCC2 in the thick ascending limb: role of protein kinase AProstaglandin E2-activated Epac promotes neointimal formation of the rat ductus arteriosus by a process distinct from that of cAMP-dependent protein kinase ADifferential distribution of exchange proteins directly activated by cyclic AMP within the adult rat retinaRap1-mediated activation of extracellular signal-regulated kinases by cyclic AMP is dependent on the mode of Rap1 activationExchange protein directly activated by cAMP encoded by the mammalian rapgef3 gene: Structure, function and therapeuticsDissecting the mechanism of Epac activation via hydrogen-deuterium exchange FT-IR and structural modeling.The cAMP-responsive Rap1 guanine nucleotide exchange factor, Epac, induces smooth muscle relaxation by down-regulation of RhoA activity.Akt and ERK1/2 pathways are components of the vasopressin signaling network in rat native IMCDA Rap/phosphatidylinositol 3-kinase pathway controls pseudopod formation [corrected].Cell cycle-dependent subcellular localization of exchange factor directly activated by cAMP.Data recovery and integration from public databases uncovers transformation-specific transcriptional downregulation of cAMP-PKA pathway-encoding genes.Prostaglandin promotion of osteocyte gap junction function through transcriptional regulation of connexin 43 by glycogen synthase kinase 3/beta-catenin signaling.Epac, not PKA catalytic subunit, is required for 3T3-L1 preadipocyte differentiation.Phosphorylation of endothelial NOS contributes to simvastatin protection against myocardial no-reflow and infarction in reperfused swine hearts: partially via the PKA signaling pathway.Lung endothelial barrier protection by iloprost in the 2-hit models of ventilator-induced lung injury (VILI) involves inhibition of Rho signaling.Effect of ligands that increase cAMP on caerulein-induced zymogen activation in pancreatic acini.Modulation of angiotensin II-induced inflammatory cytokines by the Epac1-Rap1A-NHE3 pathway: implications in renal tubular pathobiology.Pituitary adenylate cyclase-activating polypeptide (PACAP)/PAC1HOP1 receptor activation coordinates multiple neurotrophic signaling pathways: Akt activation through phosphatidylinositol 3-kinase gamma and vesicle endocytosis for neuronal survivalSignaling in sperm: toward a molecular understanding of the acquisition of sperm motility in the mouse epididymis.Stimulation of Adenosine A2B Receptor Inhibits Endothelin-1-Induced Cardiac Fibroblast Proliferation and α-Smooth Muscle Actin Synthesis Through the cAMP/Epac/PI3K/Akt-Signaling PathwayDiffering in vitro survival dependency of mouse and rat NG2+ oligodendroglial progenitor cells.AKAP9 regulation of microtubule dynamics promotes Epac1-induced endothelial barrier propertiesMechanism of intracellular cAMP sensor Epac2 activation: cAMP-induced conformational changes identified by amide hydrogen/deuterium exchange mass spectrometry (DXMS).Hepatocyte proliferation during liver regeneration is impaired in mice with methionine diet-induced hyperhomocysteinemia.Regulation of sodium-proton exchanger isoform 3 (NHE3) by PKA and exchange protein directly activated by cAMP (EPAC).5-Cyano-6-oxo-1,6-dihydro-pyrimidines as potent antagonists targeting exchange proteins directly activated by cAMP.A novel EPAC-specific inhibitor suppresses pancreatic cancer cell migration and invasion
P2860
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P2860
Differential signaling of cyclic AMP: opposing effects of exchange protein directly activated by cyclic AMP and cAMP-dependent protein kinase on protein kinase B activation.
description
2002 nî lūn-bûn
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2002 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
name
Differential signaling of cycl ...... n protein kinase B activation.
@ast
Differential signaling of cycl ...... n protein kinase B activation.
@en
Differential signaling of cycl ...... n protein kinase B activation.
@nl
type
label
Differential signaling of cycl ...... n protein kinase B activation.
@ast
Differential signaling of cycl ...... n protein kinase B activation.
@en
Differential signaling of cycl ...... n protein kinase B activation.
@nl
prefLabel
Differential signaling of cycl ...... n protein kinase B activation.
@ast
Differential signaling of cycl ...... n protein kinase B activation.
@en
Differential signaling of cycl ...... n protein kinase B activation.
@nl
P2093
P356
P1476
Differential signaling of cycl ...... n protein kinase B activation.
@en
P2093
Fang C Mei
Jingbo Qiao
Judy L Meinkoth
Lawrence A Quilliam
Oxana M Tsygankova
Xiaodong Cheng
P304
11497-11504
P356
10.1074/JBC.M110856200
P407
P577
2002-01-18T00:00:00Z